Issue 7, 2021

N-Doped carbon as a solid base catalyst for continuous flow Knoevenagel condensation

Abstract

The application of N-doped carbon as a basic, heterogeneous catalyst in a continuous-flow process is described for the first time. The Knoevenagel condensation reaction was chosen to demonstrate the potential of N-doped carbon toward the development of sustainable, scalable processes that require a basic catalyst. The practical potential and performance advantages of the flow approach compared to a conventional batch system were envisioned. Under flow conditions, products were continuously synthesized for 200 h with high conversions up to 95%. The presented metal-free flow system successfully operated under mild reaction conditions, with temperatures ranging from 25 to 70 °C and ethanol as a solvent, which embody key principles of green chemistry.

Graphical abstract: N-Doped carbon as a solid base catalyst for continuous flow Knoevenagel condensation

Supplementary files

Article information

Article type
Paper
Submitted
09 Jan 2021
Accepted
13 Apr 2021
First published
13 Apr 2021

React. Chem. Eng., 2021,6, 1246-1253

N-Doped carbon as a solid base catalyst for continuous flow Knoevenagel condensation

A. Brzęczek-Szafran, M. Gwóźdź, A. Kolanowska, M. Krzywiecki, P. Latos and A. Chrobok, React. Chem. Eng., 2021, 6, 1246 DOI: 10.1039/D1RE00016K

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