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Letters in Organic Chemistry

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ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

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Letter Article

Synthesis of Pyrazole-Carboxamides and Pyrazole-Carboxylic Acids Derivatives: Simple Methods to Access Powerful Building Blocks

Author(s): Byanca Silva Ferreira, Rafaela Corrêa Silva, Bernardo Araújo Souto and Maurício Silva dos Santos*

Volume 18, Issue 5, 2021

Published on: 28 July, 2020

Page: [335 - 343] Pages: 9

DOI: 10.2174/1570178617999200728215322

Price: $65

Abstract

Hybrid systems containing pyrazole moiety show a wide spectrum of biological activities. To access novel hybrids with pyrazole ring, in this work we synthesized twenty pyrazole-carboxylic acids and twenty pyrazole-carboxamides, using simple synthetic methods, to be used as building blocks in the development of new structures.

Keywords: Pyrazole, carboxylic acids, carboxamides, heterocyclic derivatives, synthesis, pyrazole hybrids.

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