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PVA/gelatin-based hydrogel coating of nickel-titanium alloy for improved tissue-implant interface

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Abstract

Nickel-titanium shape memory alloys have attracted notable interest for biomedical applications due to their unique properties. However, there are still some concerns on the potential release of nickel ions causing adverse reactions in-vivo at high concentrations. In this work, samples were coated with a polyvinyl alcohol/gelatin hydrogel. Coating stability, corrosion resistance and biocompatibility were investigated. Coated samples exhibited similar shape memory response to that of the uncoated substrates in wire form. Additionally, the hydrogel coating led to a decrease in the surface temperature and significantly improved the corrosion resistance of the shape memory substrate. The presence of the hydrogel layer does not affect the biocompatibility of the alloy while providing a semi-degradable, hydrophilic surface that forms a cushion at the tissue-implant interfaces.

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References

  1. T. Duerig, A. Pelton, D. Stöckel, Mater. Sci. Eng. 273, 149 (1999)

    Article  Google Scholar 

  2. K. Otsuka, C.M. Wayman, Shape Memory Materials (Cambridge University Express, Cambridge, 1999).

    Google Scholar 

  3. L. Machado, M. Savi, Braz. J. Med. Biol. Res. 36, 683 (2003)

    Article  Google Scholar 

  4. A.T. Tung, B.H. Park, D.H. Liang, G. Niemeyer, Sens. Actuators A Phys. 147, 83 (2008)

    Article  Google Scholar 

  5. A. Vahidyeganeh, G. Simsek, S. Jabeen, O. Bebek, G.G. Yapici, Mater. Sci. Forum 887, 104 (2017)

    Article  Google Scholar 

  6. N. Muhammad, D. Whitehead, A. Boor, W. Oppenlander, Z. Liu, L. Li, Appl. Phys. A 106, 607 (2012)

    Article  ADS  Google Scholar 

  7. S. Kujala, J. Ryhänen, T. Jämsä, A. Danilov, J. Saaranen, A. Pramila, J. Tuukkanen, Biomaterials 23, 2535 (2002)

    Article  Google Scholar 

  8. J. Khalil-Allafi, B. Amin-Ahmadi, M. Zare, Mater. Sci. Eng. C 30, 1112 (2010)

    Article  Google Scholar 

  9. L. Jinlong, L. Tongxiang, W. Chen, D. Limin, Mater. Sci. Eng. C 63, 192 (2016)

    Article  Google Scholar 

  10. L.A. Bravo, A.G. Cabanes, J.M. Manero, E. Ruperez, F.J. Gil, J. Mater. Sci. Mater. Med. 25, 555 (2014)

    Article  Google Scholar 

  11. F.J. Garcia-Sanz, M.B. Mayor, J.L. Arias, J. Pou, B. Leon, M. Perez-Amor, J. Mater. Sci. Mater. Med. 8, 861 (1997)

    Article  Google Scholar 

  12. P. Xu, G. Meng, L. Pershin, J. Mostaghimi, T.W. Coyle, J. Mater. Res. Technol. 62, 107 (2021)

    Google Scholar 

  13. S. Khamseh, E. Alibakhshi, B. Ramezanzadeh, M.G. Sari, Chem. Eng. J. 404, 126490 (2021)

    Article  Google Scholar 

  14. D. Batalu, F. Nastase, M. Militaru, M. Gherghiceanu, P. Badica, J. Mater. Res. Technol. 8(1), 914–922 (2018)

    Article  Google Scholar 

  15. E. Ruperez, J.M. Manero, L.A. Gonzalez, E. Espinar, F.J. Gil, Mater. Basel 9, 402 (2016)

    ADS  Google Scholar 

  16. J. Choi, D. Bogdanski, M. Köller, S.-A. Esenwein, D. Müller, G. Muhr, M. Epple, Biomaterials 24, 3689 (2003)

    Article  Google Scholar 

  17. C.-F. Dunne, K. Roche, B. Twomey, K.-T. Stanton, Mater. Lett. 176, 185 (2016)

    Article  Google Scholar 

  18. C. Gebelein, F. Koblitz, Biomedical and Dental Applications of Polymers (Springer, Berlin, 2013).

    Google Scholar 

  19. E. Caló, V.-V. Khutoryanskiy, Eur. Polym. J. 65, 252 (2015)

    Article  Google Scholar 

  20. E.A. Kamoun, E.S. Kenawy, X. Chen, J. Adv. Res. 8, 217 (2017)

    Article  Google Scholar 

  21. K. Pal, A.-K. Banthia, D.-K. Majumdar, AAPS Pharm. Sci. Tech. 8, 142 (2007)

    Article  Google Scholar 

  22. S. Pawde, K. Deshmukh, J. Appl. Polym. Sci. 109, 3431 (2008)

    Article  Google Scholar 

  23. H. Knopf-Marques, J. Barthes, L. Wolfova, B. Vidal, G. Koenig, J. Bacharouche, G.-G. Francius, H. Sadam, U. Liivas, P. Lavalle, ACS Omega 2, 918 (2017)

    Article  Google Scholar 

  24. N.E. Vrana, P.A. Cahill, G.B. McGuinness, J. Biomed. Mater. Res. A. 94(4), 1080 (2010)

    Google Scholar 

  25. N.E. Vrana, K. Matsumura, S.H. Hyon, L.M. Geever, J.E. Kennedy, J.G. Lyons, C.L. Higginbotham, P.A. Cahill, G.B. McGuinness, J. Tissue Eng. Regen. Med. 6(4), 280 (2012)

    Article  Google Scholar 

  26. P.K. Sahoo, P.K. Rana, S.K. Swain, Int. J. Polym. Mater. Polym. Biomater. 55, 65 (2006)

    Article  Google Scholar 

  27. M. Pulat, N. Ugurlu, Soft Mater. 14(4), 217 (2016)

    Article  Google Scholar 

  28. F. Mansfeld, The Polarization Resistance Technique for Measuring Corrosion Currents Advances in Corrosion Science and Technology (Springer, Boston, 1976), pp. 163–262

    Google Scholar 

  29. ISO 10993–5, Biological Evaluation of Medical Devices. (2009) Part 5

  30. X. Huang, Y. Liu, Scr. Mater. 45, 153 (2001)

    Article  Google Scholar 

  31. H. Cheng, K. Yue, M. Kazemzadeh-Narbat, Y. Liu, A. Khalilpour, L. Bingyun, Y.S. Zhang, N. Annabi, A. Khademhosseini, Adv. Mater. Interfaces 9, 11428 (2017)

    Article  Google Scholar 

  32. L. D’eramo, B. Chollet, M. Leman, E. Martwong, M. Li, H. Geisler, J. Dupire, M. Kerdraon, C. Vergne, F. Monti, Y. Tran, P. Tabeling, Microsyst. Nanoeng. 4, 17069 (2018)

    Article  Google Scholar 

  33. R.T. Hassarati, W.F. Dueck, C. Tasche, P.M. Carter, L.A. Poole-Warren, R.A. Green, IEEE Trans. Neural Syst. Rehabil. Eng. 22(2), 411 (2014)

    Article  Google Scholar 

  34. A. Niemczyk, M. El Fray, S.E. Franklin, Tribol. Int. 89, 54 (2015)

    Article  Google Scholar 

  35. J. Barthes, P. Lagarrigue, V. Riabov, G. Lutzweiler, J. Kirsch, C. Muller, E.-J. Courtial, C. Marquette, F. Projetti, J. Kzhyskowska, P. Lavalle, N.E. Vrana, A. Dupret-Bories, Biomaterials 268, 120549 (2021)

    Article  Google Scholar 

  36. E. Larraneta, S. Stewart, M. Ervine, R. Al-Kasasbeh, R.F. Donnely, J. Funct. Biomater. 9, 13 (2018)

    Article  Google Scholar 

  37. N. Kashyap, N. Kumar, M.N.V.R. Kumar, Crit. Rev. Ther. Drug Carr. Syst. 22, 107 (2005)

    Article  Google Scholar 

  38. J. Maia, M.P. Ribeiro, C. Ventura, R.A. Carvalho, I.J. Correia, M.H. Gil, ActaBiomater. 2009, 5 (1948)

    Google Scholar 

  39. M. Trzaskowski, B. Butruk, T. Ciach, Chall. Mod. Technol. 2(1), 19 (2011)

    Google Scholar 

  40. J. Wen, J. Lei, J. Chen, J. Guo, Y. Li, L. Li, Chem. Engr. J. 5(2), 123742 (2020)

    Article  Google Scholar 

  41. S. Devikala, P. Kamaraj, M. Arthanareeswari, Mater. Today Proc. 5, 8672 (2018)

    Article  Google Scholar 

  42. H.W. Zhu, J.N. Zhang, P. Su, T. Liu, C. He, D. Feng, H. Wang, Soft. Matter. 16, 709 (2020)

    Article  ADS  Google Scholar 

  43. M. Saveleva, A. Vladescu, C. Cotrut, L.V. Meeren, M. Surmeneva, R. Surmenev, B. Parakhonskiy, A.G. Skirtach, J. Mater. Chem. B. 7, 6778 (2019)

    Article  Google Scholar 

  44. E. Ruperez, J.M. Manero, L.A.B. Gonzalez, E. Espinar, F.J. Gil, Materials 9, 402 (2016)

    Article  ADS  Google Scholar 

  45. G.M. Simsek, G.G. Yapici, Mater. Sci. Forum 986, 55–60 (2020)

    Article  Google Scholar 

  46. M. Chembath, J.N. Balaraju, M. Sujata, Surf. Coat. Technol. 302, 302–309 (2016)

    Article  Google Scholar 

  47. K.W.K. Yeung, R.W.Y. Poon, X.Y. Liu, J.P.Y. Ho, J. Biomed. Mater. Res. A 75A, 256 (2005)

    Article  Google Scholar 

Download references

Acknowledgements

The authors would like to acknowledge the support from The Scientific and Technological Research Council of Turkey (TUBITAK) within Project no: 113S096 and the EU Horizon 2020 research and innovation programme under Grant agreement No: 760921 (PANBioRA).

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Authors and Affiliations

  1. Mechanical Engineering Department, Ozyegin University, 34794, Istanbul, Turkey

    G. M. Simsek & G. G. Yapici

  2. Mechanics and Manufacturing of Functional and Structural Materials Lab. (MEMFIS), Ozyegin University, Istanbul, Turkey

    G. M. Simsek & G. G. Yapici

  3. INSERM UMR 1121, 11 rue Humann, 67085, Strasbourg, France

    J. Barthes, C. Muller & N. E. Vrana

  4. Dublin City University, Dublin, Ireland

    G. B. McGuinness

  5. SPARTHA Medical, 14B Rue de la Canardiere, 67100, Strasbourg, France

    N. E. Vrana

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  1. G. M. Simsek
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  4. G. B. McGuinness
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Correspondence to G. G. Yapici.

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Simsek, G.M., Barthes, J., Muller, C. et al. PVA/gelatin-based hydrogel coating of nickel-titanium alloy for improved tissue-implant interface. Appl. Phys. A 127, 387 (2021). https://doi.org/10.1007/s00339-021-04542-5

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