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Review on the Optical Properties of Nanoparticle Aggregates Towards the Therapeutic Applications

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Abstract

Nanoparticles are of potential use for therapeutic applications, and nowadays a variety of modalities involving optical characteristics of nanoparticles are in the clinical translation stage. The optical properties of nanoparticles depend on their dimension and shape, wherein the larger size of the nanoparticles, as well as proximity of the nanoparticles within the near-field limit, lead to resonance peak shift in the optical spectrum. For a nanoparticle, the optical characteristics are influenced due to its aggregation and thereby critically govern the therapeutic outcome. In this article, a concise and step-by-step review of the optical properties of the nanoparticles and their aggregates is conducted. This will be useful towards the practical application for a variety of therapeutic modalities utilizing optical characteristics of nanoparticles.

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Acknowledgements

D.P. acknowledges the CSIR-India for the Nehru Science Postdoctoral Research Fellowship number HRDG/CSIR-Nehru PDF/EN, ES & PS/EMR-I/04/2019. D.P. and S.S. acknowledge the support of the CSIR-CSIO Chandigarh for hosting the research.

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  1. Biomedical Instrumentation Division, CSIR-Central Scientific Instruments Organisation, Sector-30C, Chandigarh, 160030, India

    Dheeraj Pratap & Sanjeev Soni

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  1. Dheeraj Pratap
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Dheeraj Pratap wrote the review manuscript and Sanjeev Soni edited and suggested required modifications.

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Pratap, D., Soni, S. Review on the Optical Properties of Nanoparticle Aggregates Towards the Therapeutic Applications. Plasmonics 16, 1495–1513 (2021). https://doi.org/10.1007/s11468-021-01443-4

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