Abstract
Antisolvent crystallization method of 2-chloro-4,6-dinitroresorcinol was proposed and discussed for the first time. The yield of the product crystals was over 92.5%. Crystallization was carried out under the ambient temperature; ethanol was used as a solvent and water was used as an antisolvent. The technological conditions of antisolvent feed rate were studied, and 0.75 mL/min was the best operation. The solubility of 2-chloro-4,6-dinitroresorcinol in ethanol/water mixtures at 293.15–343.15 K was determined, and the Jouyban–Acree solubility equation was established. The mean deviation between experimental values and calculated ones was 1.81%.
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Funding
This work was supported by the National High Technology Research and Development Program of China (Program 863, no. 2012AA03A212) and Liaoning Province Department of Education Foundation (no. 901073).
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Zhang, L., Yuan, H.Q. Antisolvent Crystallization Method and Mixed Solvent Solubility Model Study of 2-Chloro-4,6-Dinitroresorcinol. Theor Found Chem Eng 55, 123–128 (2021). https://doi.org/10.1134/S0040579521010176
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DOI: https://doi.org/10.1134/S0040579521010176