Abstract
Procedures are developed for the quantitative determination of proteins, recombinant thrombin, and hemagglutinin on the influenza A virus, based on the SERS effect observed on aggregates of silver nanoparticles modified with aptamers to thrombin and hemagglutinin, respectively.
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Funding
Our work on the detection of proteins (thrombin and albumin) was supported by the Russian Science Foundation, grant no. 19-72-30003.
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Translated by V. Kudrinskaya
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Gribanev, D.A., Zavyalova, E.G., Gambaryan, A.S. et al. Investigating Aptamer-Functionalized Silver Nanoparticles as SERS Substrates for Selective Protein Detection. Bull. Russ. Acad. Sci. Phys. 85, 127–132 (2021). https://doi.org/10.3103/S1062873821020106
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DOI: https://doi.org/10.3103/S1062873821020106