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Creating opportunities in cancer research

Cancer research has undergone transformational changes over the past several decades. On the occasion of the 20th anniversary of the establishment of the NCI Center for Cancer Research, we highlight some elements that enable successful institutional approaches to solving the most pressing problems in cancer research.

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Fig. 1: Key elements for successful institutional approaches to cancer research.

References

  1. Roskoski, R. Pharmacol. Res. https://doi.org/10.1016/j.phrs.2021.105463 (2021).

  2. Rosenberg, S. A. & Restifo, N. P. Science 348, 62–68 (2015).

    Article  CAS  Google Scholar 

  3. Topalian, S. L., Drake, C. G. & Pardoll, D. M. Cancer Cell 27, 450–461 (2015).

    Article  CAS  Google Scholar 

  4. Lowy, D. R. & Schiller, J. T. J. Am. Med. Assoc. 318, 901–902 (2017).

    Article  Google Scholar 

  5. Serrano, M. J. et al. Cancer Discov. 10, 1635–1644 (2020).

    Article  Google Scholar 

  6. Yin, H., Xue, W. & Anderson, D. G. Nat. Rev. Clin. Oncol. 16, 281–295 (2019).

    Article  CAS  Google Scholar 

  7. Jiang, P., Sellers, W. R. & Liu, X. S. Annu. Rev. Biomed. Data Sci. 1, 1–27 (2018).

    Article  Google Scholar 

  8. Krummel, M. et al. Cancer Cell 38, 753–756 (2020).

    Article  CAS  Google Scholar 

  9. Kaluzny, A. D. & O’Brien, D. M. Health Policy Open 1, 100015 (2020).

    Article  Google Scholar 

  10. Thompson, C. B. Cell 138, 1051–1054 (2009).

    Article  CAS  Google Scholar 

  11. Ramsey, B. W., Nepom, G. T. & Lonial, S. N. Engl. J. Med. 376, 1762–1769 (2017).

    Article  CAS  Google Scholar 

  12. Gaur, S. et al. AJR Am. J. Roentgenol. 215, 652–659 (2020).

    Article  Google Scholar 

  13. Jain, M. K. et al. N. Engl. J. Med. 381, 399–402 (2019).

    Article  Google Scholar 

  14. Noble, K. et al. Nat. Cancer 1, 139–141 (2020).

    Article  Google Scholar 

  15. Swartz, T. H., Palermo, A. S., Masur, S. K. & Aberg, J. A. J. Infect. Dis. 220, S33–S41 (2019).

    Article  Google Scholar 

  16. American Association for Cancer Research. https://cancerprogressreport.aacr.org/disparities/ (2020).

Download references

Acknowledgements

The opinions expressed in this article are the authors' own and do not reflect the views of the National Institutes of Health, the Department of Health and Human Services or the United States government.

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Correspondence to Tom Misteli.

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Dahut, W., Merlino, G. & Misteli, T. Creating opportunities in cancer research. Nat Cancer 2, 247–250 (2021). https://doi.org/10.1038/s43018-021-00187-8

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