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Effect of Precipitant on Conformational State of Silk Fibroin in Ionic-Liquid Solutions

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Fibre Chemistry Aims and scope

Silk fibroin fiber is a unique biopolymer with high potential for medical applications. Dissolution and regeneration of fibroin using traditional solvents causes conformational transformations of the native fibroin structure and poor physicomechanical characteristics of materials prepared from it. The supramolecular structure can be regulated during precipitation. Herein, regeneration of fibroin using ionic liquids was investigated using IR spectroscopy and x-ray structure analysis. MeOH was shown to be the strongest precipitant for fibroin solutions in ionic liquids and could produce a supramolecular structure close to that of native fibroin. The fibroin precipitation conditions were mollified if alcohols with hydrocarbon radicals increasing in the order C1-C4 were used as precipitants.

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Authors and Affiliations

  1. St. Petersburg State University of Industrial Technologies and Design, St. Petersburg, Russia

    A. I. Susanin, E. S. Sashina & E. V. Gumalevskaya

  2. B. P. Konstantinov Petersburg Nuclear Physics Institute, National Research Center Kurchatov Institute, St. Petersburg, Russia

    V. V. Zakharov

  3. Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia

    V. V. Zakharov

  4. Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia

    V. V. Zakharov

  5. Lodz University of Technology, Lodz, Poland

    W. Maniukiewicz & M. Zaborski

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  1. A. I. Susanin
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  2. E. S. Sashina
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  5. E. V. Gumalevskaya
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Correspondence to A. I. Susanin.

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Translated from Khimicheskie Volokna, No. 4, pp. 22-27, July—August, 2020.

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Susanin, A.I., Sashina, E.S., Maniukiewicz, W. et al. Effect of Precipitant on Conformational State of Silk Fibroin in Ionic-Liquid Solutions. Fibre Chem 52, 253–258 (2020). https://doi.org/10.1007/s10692-021-10191-4

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  • DOI: https://doi.org/10.1007/s10692-021-10191-4

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