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Neuroendocrine Tumors of the Thyroid and Their Mimics

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Abstract

This paper will review neuroendocrine lesions of the thyroid and the differential diagnosis with the most significant such tumor of the thyroid, that is, medullary thyroid carcinoma. A brief overview of the understanding of this tumor's identification as a lesion of C cells and its familial and syndromic associations will be presented. Then, a discussion of the various mimics of medullary carcinoma will be given with an approach to the types of tests that can be done to arrive at a correct diagnostic conclusion. This review will focus on practical “tips” for the practicing pathologist.

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Acknowledgement

This paper was presented as part of the proceedings of the USCAP 2021 Endocrine Pathology Society Companion Meeting.

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  1. Department of Pathology and Laboratory Medicine, Perelmann School of Medicine, University of Pennsylvania, Philadelphia, USA

    Virginia A Livolsi

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Livolsi, V.A. Neuroendocrine Tumors of the Thyroid and Their Mimics. Endocr Pathol 32, 211–221 (2021). https://doi.org/10.1007/s12022-021-09672-3

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