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ON EXISTENCE AND UNIQUENESS OF SOLUTIONS TO A PANTOGRAPH TYPE EQUATION

Published online by Cambridge University Press:  03 March 2021

M. MOHSIN
Affiliation:
Department of Mathematics, Lahore University of Management Sciences, Lahore, Pakistan; e-mail: muhammad.mohsin@lums.edu.pk
A. A. ZAIDI*
Affiliation:
Department of Mathematics, Lahore University of Management Sciences, Lahore, Pakistan; e-mail: muhammad.mohsin@lums.edu.pk

Abstract

We show existence and uniqueness of solutions to an initial boundary value problem that entails a pantograph type functional partial differential equation with two advanced nonlocal terms. The problem models cell growth and division into two daughter cells of different sizes. There is a paucity of information about the solution to the problem for an arbitrary initial cell distribution.

Type
Research Article
Copyright
© Australian Mathematical Society 2021

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References

Diekmann, O., Heijmans, H. J. A. M. and Thieme, H. R., “On the stability of the cell size distribution”, J. Math. Biol. 19 (1984) 227248; doi:10.1007/BF00277748.CrossRefGoogle Scholar
Efendiev, M., van-Brunt, B., Zaidi, A. A. and Shah, T. H., “Asymmetric cell division with stochastic growth rate”, Math. Methods Appl. Sci. 41 (2018) 80598069; doi:10.1002/mma.5269.CrossRefGoogle Scholar
Efendiev, M. A., van Brunt, B., Wake, G. C. and Zaidi, A. A., “A functional partial differential equation arising in a cell growth model with dispersion”, Math. Methods Appl. Sci. 41 (2018) 15411553; doi:10.1002/mma.4684.CrossRefGoogle Scholar
Gönczy, P., “Mechanisms of asymmetric cell division: flies and worms pave the way”, Nat. Rev. Mol. Cell Biol. 9 (2008) 355366; doi:10.1038/nrm2388.CrossRefGoogle ScholarPubMed
Hall, A. J. and Wake, G. C., “A functional differential equation arising in modelling of cell growth”, J. Aust. Math. Soc. Ser. B 30 (1989) 424435; doi:10.1017/S0334270000006366.CrossRefGoogle Scholar
Hall, A. J. and Wake, G. C., “A functional differential equation determining steady size distributions for populations of cells growing exponentially”, J. Aust. Math. Soc. Ser. B 31 (1990) 344353; doi:10.1017/S0334270000006779.CrossRefGoogle Scholar
Morrison, S. J. and Kimble, J., “Asymmetric and symmetric stem-cell divisions in development and cancer”, Nature 441 (2006) 10681074; doi:10.1038/nature04956.CrossRefGoogle ScholarPubMed
Neumüller, R. A. and Knoblich, J. A., “Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer”, Genes Dev. 23 (2009) 26752699; doi:10.1101/gad.1850809.CrossRefGoogle ScholarPubMed
Perthame, B. and Ryzhik, L., “Exponential decay for the fragmentation or cell-division equation”, J. Differ. Equ. 210 (2005) 155177; doi:10.1016/j.jde.2004.10.018.CrossRefGoogle Scholar
Thorpe, P. H., Bruno, J. and Rothstein, R., “Modeling stem cell asymmetry in yeast”, Cold Spring Harb. Symp. Quant. Biol. 73 (2008) 8188; doi:10.1101/sqb.2008.73.010.CrossRefGoogle ScholarPubMed
van Brunt B, B., Almalki, A., Lynch, T. and Zaidi, A., “On a cell division equation with a linear growth rate”, ANZIAM J. 59 (2018) 293312. doi:10.1017/S1446181117000591.Google Scholar
Wake, G. C., Cooper, S., Kim, H.K. and van Brunt, B., “Functional differential equations for cell-growth models with dispersion”, Commun. Appl. Anal. 4 (2000) 561574.Google Scholar
Zaidi, A. A., van Brunt, B. and Wake, G. C., “A model for asymmetrical cell division”, Math. Biosci. Eng. 12 (2015) 491501; doi:10.3934/mbe.2015.12.491.CrossRefGoogle Scholar
Zaidi, A. A., van Brunt, B. and Wake, G. C., “Solutions to an advanced functional partial differential equation of the pantograph type”, Proc. R. Soc. A 471 (2015) 20140947; doi:10.1098/rspa.2014.0947.CrossRefGoogle Scholar
Zaidi, A. A., van Brunt, B. and Wake, G. C., “Probability density function solutions to a Bessel type pantograph equation”, Appl. Anal. 95 (2016) 25652577; doi:10.1080/00036811.2015.1102890.CrossRefGoogle Scholar