Skip to main content
SpringerLink
Log in

A Decade of Russian Metabolomics: the History of Development and Achievements

  • Published:
Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry Aims and scope Submit manuscript

Abstract—

Metabolomics is one of the omics sciences, its technologies are widely used in many life sciences. Application of metabolomics had a significant impact on the discovery of new biomarkers of diseases, the description of biochemical processes occurring in many organisms; it created a basis for a new generation of clinical laboratory diagnostics. The purpose of this review is to demonstrate how metabolomics is represented in the studies of Russian scientists, to demonstrate the main directions and achievements of the Russian science in this field. The review also highlights the history of metabolomics, existing problems and the place of Russian metabolomics in their solution.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.
Fig. 2.
Fig. 3.

Similar content being viewed by others

REFERENCES

  1. Gieger, C., Geistlinger, L., Altmaier, E., de Angelis, M.H., Kronenberg, F., Meitinger, T., Mewes, H.W., Wichmann, H.E., Weinberger, K.M., Adamski, J., Illig, T., and Suhre K., PLoS Genet., 2008, vol. 4, no. 11, e1000282.https://doi.org/10.1371/journal.pgen.1000282

  2. Johnson, C.H., Ivanisevic, J., and Siuzdak, G., Nat. Rev. Mol. Cell Biol., 2016, vol. 17, pp. 451–459. https://doi.org/10.1038/nrm.2016.25

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Mathew, A.K. and Padmanaban, V.C., Int. J. Pharm. Pharm. Sci., 2013, vol. 5, pp. 45–48.

    Google Scholar 

  4. Pinu, F.R., Goldansaz, S.A., and Jaine, J., Metabolites, 2019, vol. 9, no. 6, 108.https://doi.org/10.3390/metabo9060108

  5. Oliver, S.G., Winson, M.K., Kell, D.B., and Baganz, F., Trends Biotechnol., 1998, vol. 16, pp. 373−378. https://doi.org/10.1016/S0167-7799(98)01214-1

    Article  CAS  PubMed  Google Scholar 

  6. Fiehn, O., in Functional Genomics, Town, C., Ed., Dordrecht: Springer, 2002, pp. 155−171. https://doi.org/10.1007/978-94-010-0448-0_11

    Book  Google Scholar 

  7. Wishart, D.S., Nat. Rev. Drug Discov., 2016, vol. 15, pp. 473−484. https://doi.org/10.1038/nrd.2016.32

    Article  CAS  PubMed  Google Scholar 

  8. Kell, D.B. and Oliver, S.G., Metabolomics, 2016, vol. 12, 148. https://doi.org/10.1007/s11306-016-1108-4

  9. Smith, C.A., O’Maille, G., Want, E.J., Qin, C., Trauger, S.A., Brandon, T.R., Custodio, D.E., Abagyan, R., and Siuzdak, G., Therapeutic Drug Monitoring, 2005, vol. 27, pp. 747−751. https://doi.org/10.1097/01.ftd.0000179845.53213.39

    Article  CAS  PubMed  Google Scholar 

  10. Beger, R.D., Dunn, W.B., Bandukwala, A., Bethan, B., Broadhurst, D., Clish, C.B., Dasari, S., Derr, L., Evans, A., Fischer, S., Flynn, T., Hartung, T., Herrington, D., Higashi, R., Hsu, P.C., Jones, C., Kachman, M., Karuso, H., Kruppa, G., Lippa, K., Maruvada, P., Mosley, J., Ntai, I., O’Donovan, C., Playdon, M., Raftery, D., Shaughnessy, D., Souza, A., Spaeder, T., Spalholz, B., Tayyari, F., Ubhi, B., Verma, M., Walk, T., Wilson, I., Witkin, K., Bearden, D.W., and Zanetti, K.A., Metabolomics, 2019, vol. 15, 4.https://doi.org/10.1007/s11306-018-1460-7

  11. Beale, D.J., Pinu, F.R., Kouremenos, K.A., Poojary, M.M., Narayana, V.K., Boughton, B.A., Kanojia, K., Dayalan, S., Jones, O.A.H., and Dias, D.A., Metabolomics, 2018, vol. 14, 152.https://doi.org/10.1007/s11306-018-1449-2

  12. Zhang, A., Sun, H., Wang, P., Han, Y., and Wang, X., Analyst, 2012, vol. 137, pp. 293−300. https://doi.org/10.1039/c1an15605e

    Article  CAS  PubMed  Google Scholar 

  13. Meier, R., Ruttkies, C., Treutler, H., and Neumann, S., J. Biotechnol., 2017, vol. 261, pp. 137−141. https://doi.org/10.1016/j.jbiotec.2017.05.018

    Article  CAS  PubMed  Google Scholar 

  14. Skelton, D.M., Ekman, D.R., Martinović-Weigelt, D., Ankley, G.T., Villeneuve, D.L., Teng, Q., and Collette, T.W., Environ. Sci. Technol., 2014, vol. 48, pp. 2395−2403. https://doi.org/10.1021/es404021f

    Article  CAS  PubMed  Google Scholar 

  15. Wishart, D.S., Trends Food Sci. Technol., 2008, vol. 19, pp. 482−493. https://doi.org/10.1016/j.tifs.2008.03.003

    Article  CAS  Google Scholar 

  16. Kim, S., Kim, J., Yun, E.J., and Kim, K.H., Curr. Opin. Biotechnol., 2016, vol. 37, pp. 16−23. https://doi.org/10.1016/j.copbio.2015.09.004

    Article  CAS  PubMed  Google Scholar 

  17. Pinu, F.R., Food Res. Int., 2015, vol. 72, pp. 80−81. https://doi.org/10.1016/j.foodres.2015.03.028

    Article  CAS  Google Scholar 

  18. Savolainen, O., Fagerberg, B., Lind, M.V., Sandberg, A.S., Ross, A.B., and Bergström, G., PLoS One, 2017, vol. 12, no. 7, e0177738. https://doi.org/10.1371/journal.pone.0177738

  19. Liu, J., Semiz, S., van der Lee, S.J., van der Spek, A., Verhoeven, A., van Klinken, J.B., Sijbrands, E., Harms, A.C., Hankemeier, T., van Dijk, K.W., van Duijn, C.M., and Demirkan, A., Metabolomics, 2017, vol. 13, 104. https://doi.org/10.1007/s11306-017-1239-2

  20. Shah, S.H., Kraus, W.E., and Newgard, C.B., Circulation, 2012, vol. 126, pp. 1110−1120. https://doi.org/10.1161/CIRCULATIONAHA.111.060368

    Article  PubMed  PubMed Central  Google Scholar 

  21. Shajahan-Haq, A.N., Cheema, M.S., and Clarke, R., Metabolites, 2015, vol. 5, pp. 100−118. https://doi.org/10.3390/metabo5010100

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. Mehta, K.Y., Wu, H.-J., Menon, S.S., Fallah, Y., Zhong, X., Rizk, N., Unger, K., Mapstone, M., Fiandaca, M.S., Federoff, H.J., and Cheema, A.K., Oncotarget, 2017, vol. 8, pp. 68899−68915.https://doi.org/10.18632/oncotarget.20324

  23. Jelonek, K. and Widłak, P., Wspolczesna Onkol., 2018, vol. 22, pp. 135−140. https://doi.org/10.5114/wo.2018.78942

    Article  CAS  Google Scholar 

  24. Corona, G., Rizzolio, F., Giordano, A., and Toffoli, G., J. Cell Physiol., 2012, vol. 227, pp. 2827−2831. https://doi.org/10.1002/jcp.24003

    Article  CAS  PubMed  Google Scholar 

  25. van der Greef, J., van Wietmarschen, H., van Ommen, B., and Verheij, E., Mass Spectrom. Rev., 2013, vol. 32, pp. 399−415. https://doi.org/10.1002/mas.21370

    Article  CAS  PubMed  Google Scholar 

  26. Markley, J.L., Brüschweiler, R., Edison, A.S., Eghbalnia, H.R., Powers, R., Raftery, D., and Wishart, D.S., Curr. Opin. Biotechnol., 2017, vol. 43, pp. 34−40. https://doi.org/10.1016/j.copbio.2016.08.001

    Article  CAS  PubMed  Google Scholar 

  27. Lokhov, P.G. and Archakov, A.I., Biomeditsinskaya Khimiya, 2008, vol. 54, pp. 497−511.

    CAS  Google Scholar 

  28. Reo, N.V., Drug Chemical Toxicol., 2002, vol. 25, pp. 375−382. https://doi.org/10.1081/DCT-120014789

    Article  CAS  Google Scholar 

  29. Lei, Z., Huhman, D.V., and Sumner, L.W., J. Biol. Chem., 2011, vol. 286, pp. 25435−25442. https://doi.org/10.1074/jbc.R111.238691

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  30. van den Berg, R.A., Hoefsloot, H.C.J., Westerhuis, J.A., Smilde, A.K., and van der Werf, M.J., BMC Genomics, 2006, vol. 7, 142.https://doi.org/10.1186/1471-2164-7-142

  31. Trifonova, O., Lokhov, P., and Archakov, A., Omi. A J. Integr. Biol., 2013, vol. 17, pp. 550−559. https://doi.org/10.1089/omi.2012.0121

    Article  CAS  Google Scholar 

  32. Sugimoto, M., Kawakami, M., Robert, M., Soga, T., and Tomita, M., Curr. Bioinform., 2012, vol. 7, pp. 96−108. https://doi.org/10.2174/157489312799304431

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  33. Dunn, W.B., Broadhurst, D.I., Atherton, H.J., Goodacre, R., and Griffin, J.L., Chem. Soc. Rev., 2011, vol. 40, pp. 387−426. https://doi.org/10.1039/b906712b

    Article  CAS  PubMed  Google Scholar 

  34. Jollife, I.T. and Cadima, J., Philos. Trans. R Soc. A Math. Phys. Eng. Sci., 2016, vol. 374, 20150202. https://doi.org/10.1098/rsta.2015.0202

  35. Scholz, M., Gatzek, S., Sterling, A., Fiehn, O., and Selbig, J., Bioinformatics, 2004, vol. 20, pp. 2447−2454. https://doi.org/10.1093/bioinformatics/bth270

    Article  CAS  PubMed  Google Scholar 

  36. Smilde, A.K., Jansen, J.J., Hoefsloot, H.C.J., Lamers, R.J.A.N., van der Greef, J., and Timme-rman, M.E., Bioinformatics, 2005, vol. 21, pp. 3043–3048. https://doi.org/10.1093/bioinformatics/bti476

    Article  CAS  PubMed  Google Scholar 

  37. Vis, D.J., Westerhuis, J.A., Smilde, A.K., and van der Greef, J., BMC Bioinformatics, 2007, vol. 8, 322. https://doi.org/10.1186/1471-2105-8-322

  38. Jonsson, P., Bruce, S.J., Moritz, T., Trygg, J., Sjöström, M., Plumb, R., Granger, J., Maibaum, E., Nicholson, J.K., Holmes, E., and Antti, H., Analyst, 2005, vol. 130, pp. 701−707. https://doi.org/10.1039/b501890k

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  39. Linden, A., J. Eval. Clin. Pract., 2006, vol. 12, pp. 132−139. https://doi.org/10.1111/j.1365-2753.2005.00598.x

    Article  PubMed  Google Scholar 

  40. Bland, J.M. and Altman, D.G., BMJ, 2000, vol. 320, 1468. https://doi.org/10.1136/bmj.320.7247.1468

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  41. Westergren, A., Karlsson, S., Andersson, P., Ohlsson, O., and Hallberg, I.R., J. Clin. Nurs., 2001, vol. 10, pp. 257−269. https://doi.org/10.1046/j.1365-2702.2001.00479.x

    Article  CAS  Google Scholar 

  42. Broeckling, C.D., Reddy, I.R., Duran, A.L., Zhao, X., and Sumner, L.W., Anal. Chem., 2006, vol. 78, pp. 4334−4341. https://doi.org/10.1021/ac0521596

    Article  CAS  PubMed  Google Scholar 

  43. Baran, R., Kochi, H., Saito, N., Suematsu, M., Soga, T., Nishioka, T., Robert, M., and Tomita, M., BMC Bioinformatics, 2006, vol. 7, 530.https://doi.org/10.1186/1471-2105-7-530

  44. Luedemann, A., Strassburg, K., Erban, A., and Kopka, J., Bioinformatics, 2008, vol. 24, pp. 732−737. https://doi.org/10.1093/bioinformatics/btn023

    Article  CAS  PubMed  Google Scholar 

  45. Denkert, C., Budczies, J., Weichert, W., Wohlge-muth, G., Scholz, M., Kind, T., Niesporek, S., Noske, A., Buckendahl, A., Dietel, M., and Fiehn, O., Mol. Cancer, 2008, vol. 7, 72.https://doi.org/10.1186/1476-4598-7-72

  46. Govorun, V.M., Moshkovskii, S.A., Tikhonova, O.V., Goufman, E.I., Serebryakova, M. V., Momyna-liev, K.T., Lokhov, P.G., Khryapova, E.V., Kudryavtseva, L.V., Smirnova, O.V., Toropyguine, I.Y., Maksimov, B.I., and Archakov, A.I., Biochemistry (Moscow), 2003, vol. 68, pp. 42−49. https://doi.org/10.1023/A:1022189200944

    Article  CAS  PubMed  Google Scholar 

  47. Lokhov, P.G., Tikhonova, O.V., Moshkovskii, S.A., Goufman, E.I., Serebriakova, M.V., Maksimov, B.I., Toropyguine, I.Y., Zgoda, V.G., Govorun, V.M., and Archakov, A.I., Proteomics, 2004, vol. 4, pp. 633−642. https://doi.org/10.1002/pmic.200300580

    Article  CAS  PubMed  Google Scholar 

  48. Kanaeva, I.P., Petushkova, N.A., Lisitsa, A.V., Lokhov, P.G., Zgoda, V.G., Karuzina, I.I., and Archakov, A.I., Toxicol. Vitr., 2005, vol. 19, pp. 805−812. https://doi.org/10.1016/j.tiv.2005.03.016

    Article  CAS  Google Scholar 

  49. Lokhov, P., Balashova, E., and Dashtiev, M., Rapid Commun. Mass Spectrom., 2009, vol. 23, pp. 680−682. https://doi.org/10.1002/rcm.3928

    Article  CAS  PubMed  Google Scholar 

  50. Balashova, E.E., Dashtiev, M.I., and Lokhov, P.G., Mol. Cell Proteomics, 2012, vol. 11, no. 2, M111.014480. https://doi.org/10.1074/mcp.M111.014480

  51. Moshkovskii, S., Pyatnitsky, M., Lokhov, P. and Baranova, A., in Biomarkers in Disease: Methods, Discoveries and Applications: Biomarkers in Cancer, Preedy, V.R. and Patel, V.B., Eds., Springer Nature Switzerland AG, 2015, pp. 3−30. https://doi.org/10.1007/978-94-007-7681-4_14

    Book  Google Scholar 

  52. Balashova, E.E. and Lokhov, P.G., J. Cancer Sci. Ther., 2010, vol. 2, pp. 126−131. https://doi.org/10.4172/1948-5956.1000037

    Article  CAS  Google Scholar 

  53. Davidov, E.J., Holland, J.M., Marple, E.W., and Naylor, S., Drug Discov. Today, 2003, vol. 8, pp. 175−183. https://doi.org/10.1016/S1359-6446(03)02600-X

    Article  CAS  PubMed  Google Scholar 

  54. Lokhov, P.G., Dashtiev, M.I., Moshkovskii, S.A., and Archakov, A.I., Metabolomics, 2010, vol. 6, pp. 156−163. https://doi.org/10.1007/s11306-009-0187-x

    Article  CAS  Google Scholar 

  55. Lokhov, P.G., Dashtiev, M.I., Bondartscov, L.V., Lisitsa, A.V., Moshkovskii, S.A., and Archakov, A.I., Biomeditsinskaya Khimiya, 2009, vol. 55, pp. 247−254.

    CAS  Google Scholar 

  56. Lokhov, P.G., Trifonova, O.P., Maslov, D.L., Balashova, E.E., Archakov, A.I., Shestakova, E.A., Shestakova, M.V., and Dedov, I.I., PLoS One, 2014, vol. 9, e105343. https://doi.org/10.1371/journal.pone.0105343

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  57. Lokhov, P.G., Kharybin, O.N., and Archakov, A.I., Int. J. Mass Spectrom., 2012, vol. 309, pp. 200–205. https://doi.org/10.1016/j.ijms.2011.10.002

    Article  CAS  Google Scholar 

  58. Lokhov, P.G., Trifonova, O.P., Maslov, D.L., and Archakov, A.I., Eur. J. Cancer Prev., 2013, vol. 22, pp. 335−341. https://doi.org/10.1097/CEJ.0b013e32835b3898

    Article  CAS  PubMed  Google Scholar 

  59. Balashova, E.E., Lokhov, P.G., Maslov, D.L., Trifonova, O.P., Khasanova, D.M., Zalyalova, Z.A., Nigmatullina, R.R., Archakov, A.I., and Ugrumov, M.V., Curr. Metabolomics, 2018, vol. 6, no. 1, 75.https://doi.org/10.2174/2213235x05666170221161735

  60. Lokhov, P.G., Balashova, E.E., Trifonova, O.P., Mas-lov, D.L., Ponomarenko, E.A., and Archakov, A.I., Int. J. Mol. Sci., 2020, vol. 21, no. 2, 568. https://doi.org/10.3390/ijms21020568

  61. Lokhov, P.G., Lisitsa, A.V., and Archakov, A.I., Biomeditsinskaya Khimiya, 2017, vol. 63, pp. 232−240. https://doi.org/10.18097/PBMC20176303232

    Article  CAS  Google Scholar 

  62. Lokhov, P.G., Maslov, D.L., Kharibin, O.N., Balashova, E.E., and Archakov, A.I., BioData Min., 2017, vol. 10, 10.https://doi.org/10.1186/s13040-017-0132-x

  63. Balashova, E.E., Lokhov, P.G., Ponomarenko, E.A., Markin, S.S., Lisitsa, A.V., and Archakov, A.I., Per. Med., 2019, vol.16, pp. 133−144. https://doi.org/10.2217/pme-2018-0066

    Article  CAS  PubMed  Google Scholar 

  64. Lokhov, P.G., Maslov, D.L., Trifonova, O.P., Balashova, E.E., and Archakov, A.I., Biomeditsinskaya Khi-miya, 2014, vol. 60, pp. 201−216. https://doi.org/10.18097/PBMC20146002201

    Article  CAS  Google Scholar 

  65. Lokhov, P.G., Maslov, D.L., Balashova, E.E., Trifonova, O.P., Medvedeva, N.V., Torkhovskaya, T.I., Ipatova, O.M., Archakov, A.I., Malyshev, P.P., Ku-kharchuk, V.V., Shestakova, E.A., Shestakova, M.V., and Dedov, I.I., Biomeditsinskaya Khimiya, 2015, vol. 61, pp. 7−18. https://doi.org/10.18097/pbmc20156101007

    Article  CAS  Google Scholar 

  66. Trifonova, O.P., Maslov, D.L., Mikhailov, A.N., Zolotarev, K.V., Nakhod, K.V., Nakhod, V.I., Belyaeva, N.F., Mikhailova, M.V., Lokhov, P.G., and Archakov, A.I., Fishes, 2018, vol. 3, no. 4, 46.https://doi.org/10.3390/fishes3040046

  67. Maslov, D.L., Trifonova, O.P., Mikhailov, A.N., Zolotarev, K.V., Nakhod, K.V., Nakhod, V.I., Belyaeva, N.F., Mikhailova, M.V., Lokhov, P.G., and Archakov, A.I., Fishes, 2019, vol. 4, no. 2, 25.https://doi.org/10.3390/fishes4020025

  68. Snytnikova, O.A., Yanshole, L.V., Iskakov, I.A., Yanshole, V.V., Chernykh, V.V., Stepakov, D.A., Novoselov, V.P., and Tsentalovich, Y.P., Metabolomics, 2017, vol. 13, 152. https://doi.org/10.1007/s11306-017-1281-0

  69. Snytnikova, O.A., Khlichkina, A.A., Yanshole, L.V., Yanshole, V.V., Iskakov, I.A., Egorova, E.V., Ste-pakov, D.A., Novoselov, V.P., and Tsentalovich, Y.P., Metabolomics, 2017, vol. 13, 5.https://doi.org/10.1007/s11306-016-1144-0

  70. Yanshole, V.V., Yanshole, L.V., Snytnikova, O.A., and Tsentalovich, Y.P., Metabolomics, 2019, vol. 15, 29. https://doi.org/10.1007/s11306-019-1495-4

  71. Kokova, D.A., Kostidis, S., Morello, J., Dementeva, N., Perina, E.A., Ivanov, V.V., Ogorodova, L.M., Sazonov, A.E., Saltykova, I.V., and Mayboroda, O.A., PLoS Negl. Trop. Dis., 2017, vol. 11, no. 10, e0006044.https://doi.org/10.1371/journal.pntd.0006044

  72. Kokova, D., Verhoeven, A., Perina, E.A., Ivanov, V.V., Knyazeva, E.M., Saltykova, I.V., and Mayboro-da, O.A., PLoS Negl. Trop. Dis., 2020, vol. 14, e0008015. https://doi.org/10.1371/journal.pntd.0008015

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  73. Puzanskiy, R.K., Yemelyanov, V.V., Gavrilenko, T.A., and Shishova. M.F. Vavilovskii Zhurnal Genetiki i Selektsii, 2017, vol. 21, no. 1, pp. 112−123. https://doi.org/10.18699/VJ17.229

    Article  Google Scholar 

  74. Puzanskiy, R.K., Yemelyanov, V.V., and Shishova, M.F., Sel’skokhozyaistvennaya Biologiya, 2018, vol. 53, pp. 15−28. https://doi.org/10.15389/agrobiology.2018.1.15eng

    Article  Google Scholar 

  75. Puzanskiy, R.K., Yemelyanov, V.V., Shavarda, A.L., Gavrilenko, T.A., and Shishova, M.F., Fiziologiya Rasteniy, 2018, vol. 65, no. 6, pp. 451−462. https://doi.org/10.18699/VJ17.229

    Article  Google Scholar 

  76. Shishova, M., Puzanskiy, R., Gavrilova, O., Kurbanniazov, S., Demchenko, K., Yemelyanov, V., Pendinen, G., Shavarda, A., and Gavrilenko, T., Metabolites, 2019, vol. 9, no. 2, 24.https://doi.org/10.3390/metabo9020024

  77. Trifonova, O.P., Lokhov, P.G., and Archakov, A.I., Biomeditsinskaya Khimiya, 2014, vol. 60, pp. 281−294. https://doi.org/10.18097/pbmc20146003281

    Article  CAS  Google Scholar 

  78. Lisitsa, A.V., Lokhov, P.G., Ponomarenko, E.A., and Archakov, A.I., Vestn. Ross. Akad. Meditsinskikh Nauk, 2016, vol. 71, pp. 255−260. https://doi.org/10.15690/vramn647

    Article  CAS  Google Scholar 

  79. Lokhov, P.G., Voskresenskaya, A.A., Trifonova, O.P., Maslov, D.L., Shestakova, E.A., Balashova, E.E., and Lisitsa, A.V., Int. J. Mass. Spectrom., 2015, vol. 388, pp. 53−58. https://doi.org/10.1016/j.ijms.2015.08.006

    Article  CAS  Google Scholar 

  80. Maslov, D.L., Trifonova, O.P., Balashova, E.E., and Lokhov, P.G., Int. J. Mol. Sci., 2019, vol. 20, no. 23, 5957. https://doi.org/10.3390/ijms20235957

  81. Trifonova, O.P., Maslov, D.L., Balashova, E.E., and Lokhov, P.G., Metabolites, 2019, vol. 9, no. 11, 277. https://doi.org/10.3390/metabo9110277

  82. Lokhov, P.G., Dashtiev, M.I., Moshkovskii, S.A., and Archakov, A.I., Metabolomics, 2009, vol. 6, pp. 156−163. https://doi.org/10.1007/s11306-009-0187-x

    Article  CAS  Google Scholar 

  83. Tabák, A.G., Herder, C., Rathmann, W., Brun-ner, E.J., and Kivimäki, M., Lancet, 2012, vol. 379, pp. 2279−2290. https://doi.org/10.1016/S0140-6736(12)60283-9

    Article  PubMed  PubMed Central  Google Scholar 

  84. McDonald, G.W., Fisher, G.F., and Burnham, C., Diabetes, 1965, vol. 14, pp. 473−480. https://doi.org/10.2337/diab.14.8.473

    Article  CAS  PubMed  Google Scholar 

  85. Ko, G.T.C., Chan, J.C.N., Woo, J., Lau, E., Yeung, V.T.F., Chow, C.C., and Cockram, C.S., Ann. Clin. Biochem., 1998, vol. 35, pp. 62−67. https://doi.org/10.1177/000456329803500107

    Article  PubMed  Google Scholar 

  86. Temelkova-Kurktschiev, T.S. and Hanefeld, M., Clin. Lab., 2002, vol. 48, pp. 143−152.

    PubMed  Google Scholar 

  87. Lokhov, P.G., Balashova, E.E., Voskresenskaya, A.A., Trifonova, O.P., Maslov, D.L., and Archakov, A.I., Biomed. Rep., 2016, vol. 4, pp. 122−126. https://doi.org/10.3892/br.2015.548

    Article  CAS  PubMed  Google Scholar 

  88. Lokhov, P.G., Trifonova, O.P., Maslov, D.L., Lichtenberg, S., and Balashova, E.E., Diagnostics, 2020, vol. 10, no. 5, 332. https://doi.org/10.3390/diagnostics10050332

    Article  CAS  PubMed Central  Google Scholar 

  89. Trifonova, O.P., Maslov, D.L., Balashova, E.E., Urazgildeeva, G.R., Abaimov, D.A., Fedotova, E.Y., Poleschuk, V.V., Illarioshkin, S.N., and Lokhov, P.G., Diagnostics, 2020, vol. 10, no. 5, 339. https://doi.org/10.3390/diagnostics10050339

    Article  CAS  PubMed Central  Google Scholar 

  90. Maslov, D.L., Balashova, E.E., Lokhov, P.G., and Archakov, A.I., Biomeditsinskaya Khimiya, 2017, vol. 63, pp. 115−123. https://doi.org/10.18097/PBMC20176302115

    Article  CAS  Google Scholar 

  91. Maslov, D.L., Balashova, E.E., Trifonova, O.P., and Lokhov, P.G., Curr. Pharmacogenomics Person. Med., 2018, vol. 16, pp. 192−198. https://doi.org/10.2174/1875692116666181008144905

    Article  CAS  Google Scholar 

  92. Balashova, E.E., Maslov, D.L., and Lokhov, P.G., J. Pers. Med., 2018, vol. 8, no. 3, 28. https://doi.org/10.3390/jpm8030028

  93. Psychogios, N., Hau, D.D., Peng, J., Guo, A.C., Mandal, R., Bouatra, S., Sinelnikov, I., Krishnamurthy, R., Eisner, R., Gautam, B., Young, N., Xia, J., Knox, C., Dong, E., Huang, P., Hollander, Z., Pedersen, T.L., Smith, S.R., Bamforth, F., Greiner, R., McManus, B., Newman, J.W., Goodfriend, T., and Wishart, D.S., PLoS One, 2011, vol. 6, no. 2, e16957.https://doi.org/10.1371/journal.pone.0016957

  94. Mishur, R.J. and Rea, S.L., Mass Spectrom. Rev., 2012, vol. 31, pp. 70−95.

    Article  CAS  Google Scholar 

  95. He, Y., Yu, Z., Giegling, I., Xie, L., Hartmann, A.M., Prehn, C., Adamski, J., Kahn, R., Li, Y., Illig, T., Wang-Sattler, R., and Rujescu, D., Transl. Psychiatry, 2012, vol. 2, e149. https://doi.org/10.1038/tp.2012.76

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  96. Gorbunova, V., Seluanov, A., Zhang, Z., Gladyshev, V.N., and Vijg, J., Nat. Rev. Genet., 2014, vol. 15, pp. 531−540. https://doi.org/10.1038/nrg3728

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  97. Selman, C. and Withers, D.J., Philos. Trans. R. Soc. B Biol. Sci., 2011, vol. 366, pp. 99−107. https://doi.org/10.1098/rstb.2010.0243

    Article  Google Scholar 

  98. Moskalev, A.A. and Pasyukova, E.G., Front. Genet., 2014, vol. 5, 276.https://doi.org/10.3389/fgene.2014.00276

  99. Rosenberg, I.H., Clin. Geriatr. Med., 2011, vol. 27, pp. 337−339. https://doi.org/10.1016/j.cger.2011.03.003

    Article  PubMed  Google Scholar 

  100.  Payne, B.A.I. and Chinnery, P.F., Biochim. Biophys. Acta. Bioenerg., 2015, vol. 1847, pp. 1347−1353. https://doi.org/10.1016/j.bbabio.2015.05.022

    Article  CAS  Google Scholar 

Download references

Funding

This study was performed within the framework of the Program for Basic Research of the Russian State Academies of Sciences for 2013–2020.

Author information

Authors and Affiliations

  1. Institute of Biomedical Chemistry, ul. Pogodinskaya 10, 119121, Moscow, Russia

    P. G. Lokhov, E. E. Balashova, O. P. Trifonova, D. L. Maslov & A. I. Archakov

Authors
  1. P. G. Lokhov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. E. Balashova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. O. P. Trifonova
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. D. L. Maslov
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. A. I. Archakov
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to E. E. Balashova.

Ethics declarations

COMPLIANCE WITH ETHICAL STANDARDS

This article does not contain any research using humans or animals as objects.

CONFLICT OF INTEREST

The authors declare that they have no conflict of in-terest.

Additional information

Translated by A. Medvedev

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lokhov, P.G., Balashova, E.E., Trifonova, O.P. et al. A Decade of Russian Metabolomics: the History of Development and Achievements. Biochem. Moscow Suppl. Ser. B 15, 1–15 (2021). https://doi.org/10.1134/S1990750821010042

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1990750821010042

Keywords:

Search

Navigation