Abstract
Decision-making competence (DMC) appears to be influenced by the congruency between the characteristics of the individual, the task and the context. Indeed, the ability to make decisions seems to be highly sensitive to cognitive changes as observed, in particular, in the healthy elderly. Few studies have investigated these relations in pathological ageing. In this review, we focus on DMC in patients with Alzheimer’s disease (AD) and the links its impairment could have with deficits in episodic memory, working memory, and executive functions. Decision-making under risk and under ambiguity appears to be impaired early in the progress of AD, with the deficit being greater during the later stages of the disease. In addition, some studies suggest that the impairment of DMC is exacerbated by deficits in other cognitive functions, in particular working memory and executive functions. This degradation in the ability to make decisions seriously affects the quality of life of patients and their relatives, since they frequently face important decisions, especially concerning healthcare, finance or accommodation. Thus, the growing incapacity to decide for themselves increases patients’ and caregivers’ stress and burden. The challenge for future studies is to determine how best to help patients and their families in the decisional process.
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References
Alameda-Bailen, J. R., Salguero-Alcaniz, M. P., Merchan-Clavellino, A., & Paino-Quesada, S. (2017). Cognitive Mechanisms in Decision-Making in Patients With Mild Alzheimer Disease. Current Alzheimer Research, 14(12), 1248–1255. https://doi.org/10.2174/1567205014666170417113834.
Bayard, S., Jacus, J. P., Raffard, S., & Gely-Nargeot, M. C. (2014). Apathy and Emotion-Based Decision-Making in Amnesic Mild Cognitive Impairment and Alzheimer’s Disease. Behavioural Neurology, 2014, 1–7. https://doi.org/10.1155/2014/231469.
Bayard, S., Jacus, J. P., Raffard, S., & Gély-Nargeot, M. C. (2015). Conscious Knowledge and Decision Making Under Ambiguity in Mild Cognitive Impairment and Alzheimer Disease. Alzheimer Disease & Associated Disorders, 29(4), 357–359. https://doi.org/10.1097/WAD.0000000000000061.
Bechara, A., & Damasio, A. R. (2005). The somatic marker hypothesis : A neural theory of economic decision. Games and Economic Behavior, 52(2), 336–372. https://doi.org/10.1016/j.geb.2004.06.010.
Bechara, A., Damasio, A. R., Damasio, H., & Anderson, S. W. (1994). Insensitivity to future consequences following damage to human prefrontal cortex. Cognition, 50(1–3), 7–15. https://doi.org/10.1016/0010-0277(94)90018-3.
Bechara, A., Damasio, H., Tranel, D., & Damasio, A. R. (1997). Deciding Advantageously Before Knowing the Advantageous Strategy. Science, 5304(275), 1293–1295.
Belleville, S., Peretz, I., & Malenfant, D. (1996). Examination of the working memory components in normal aging and in dementia of the Alzheimer type. Neuropsychologia, 34(3), 195–207. https://doi.org/10.1016/0028-3932(95)00097-6.
Bertoux, M., de Souza, L. C., Zamith, P., Dubois, B., & Bourgeois-Gironde, S. (2015). Discounting of Future Rewards in Behavioural Variant Frontotemporal Dementia & Alzheimer’s Disease. Neuropsychology, 29(6), 933–940.
Bherer, L., Belleville, S., & Hudon, C. (2004). Le déclin des fonctions exécutives au cours du vieillissement normal, dans la maladie d’Alzheimer et dans la démence frontotemporale. Psychologie et NeuroPsychiatrie du Vieillissement, 2, 9.
Braak, H., & Braak, E. (1991). Neuropathological stageing of Alzheimer-related changes. Acta Neuropathologica, 82(4), 239–259. https://doi.org/10.1007/BF00308809.
Brand, M., Labudda, K., & Markowitsch, H. J. (2006). Neuropsychological correlates of decision-making in ambiguous and risky situations. Neural Networks, 19(8), 1266–1276. https://doi.org/10.1016/j.neunet.2006.03.001.
Brand, M., Recknor, E. C., Grabenhorst, F., & Bechara, A. (2007). Decisions under ambiguity and decisions under risk : Correlations with executive functions and comparisons of two different gambling tasks with implicit and explicit rules. Journal of Clinical and Experimental Neuropsychology, 29(1), 86–99. https://doi.org/10.1080/13803390500507196.
Brand, M., Schiebener, J., Pertl, M. T., & Delazer, M. (2014). Know the risk, take the win : How executive functions and probability processing influence advantageous decision making under risk conditions. Journal of Clinical and Experimental Neuropsychology, 36(9), 914–929. https://doi.org/10.1080/13803395.2014.955783.
Buelow, M. T., & Suhr, J. A. (2009). Construct Validity of the Iowa Gambling Task. Neuropsychology Review, 19(1), 102–114. https://doi.org/10.1007/s11065-009-9083-4.
Burgio, F., Delazer, M., Meneghello, F., Pertl, M. T., Semenza, C., & Zamarian, L. (2018). Cognitive Training Improves Ratio Processing and Decision Making in Patients with Mild Cognitive Impairment. Journal of Alzheimer’s Disease, 64(4), 1213–1226. https://doi.org/10.3233/JAD-180461.
Carabellese, F., Felthous, A. R., La Tegola, D., Piazzolla, G., Distaso, S., Logroscino, G., et al. (2018). Qualitative analysis of the capacity to consent to treatment in patients with a chronic neurodegenerative disease : Alzheimer’s disease / Analisi qualitativa sulla capacità a prestare consenso al trattamento in pazienti con malattie cronico degenerative neuropsicoorganiche: Demenza di Alzheimer. International Journal of Social Psychiatry, 64(1), 26–36. https://doi.org/10.1177/0020764017739642.
Chainay, H., & Gaubert, F. (2020). Affective and cognitive theory of mind in Alzheimer’s disease : The role of executive functions. Journal of Clinical and Experimental Neuropsychology, 42(4), 371–386. https://doi.org/10.1080/13803395.2020.1726293.
Davis, R. L., & Ohman, J. M. (2016). Driving in Early-Stage of Alzheimer’s Disease : An Integrative Review of the Literature. Research in Gerontological Nursing, 10(2), 86–100. https://doi.org/10.3928/19404921-20160920-02.
Davis, R., Ziomkowski, M., & Veltkamp, A. (2017). Everyday Decision Making in Individuals with Early-Stage Alzheimer’s Disease : An Integrative Review of the Literature. Research in Gerontological Nursing, 10(5), 240–247. https://doi.org/10.3928/19404921-20170831-05.
Dawson, J. D., Anderson, S. W., Uc, E. Y., Dastrup, E., & Rizzo, M. (2009). Predictors of driving safety in early Alzheimer disease. Neurology, 72(6), 521–527. https://doi.org/10.1212/01.wnl.0000341931.35870.49.
de Siqueira, A. S. S., Yokomizo, J. E., Jacob-Filho, W., Yassuda, M. S., & Aprahamian, I. (2017). Review of Decision-Making in Game Tasks in Elderly Participants with Alzheimer Disease and Mild Cognitive Impairment. Dementia and Geriatric Cognitive Disorders, 43(1–2), 81–88. https://doi.org/10.1159/000455120.
Del Missier, F., Mäntylä, T., & De Bruin, W. B. (2012). Decision‐making competence, executive functioning, and general cognitive abilities. Journal of Behavioral Decision Making, 25(4), 331-351.
Delazer, M., Sinz, H., Zamarian, L., & Benke, T. (2007). Decision-making with explicit and stable rules in mild Alzheimer’s disease. Neuropsychologia, 45(8), 1632–1641. https://doi.org/10.1016/j.neuropsychologia.2007.01.006.
Dommes, A., Wu, Y.H., Aquino, J.P., Pitti-Ferrandi, H., Soleille, M., Martineau-Fleury, S., Samson, M., & Rigaud, A.S. (2015). Is Mild Dementia Related to Unsafe Street-Crossing Decisions?: Alzheimer Disease & Associated Disorders, 29(4), 294‑300. https://doi.org/10.1097/WAD.0000000000000074
Dubois, B., Slachevsky, A., Litvan, I., & Pillon, B. F. A. B. (2000). The FAB: a frontal assessment battery at bedside. Neurology, 55(11), 1621-1626.
Ergis, A. M., & Eusop-Roussel, E. (2008). Les troubles précoces de la mémoire épisodique dans la maladie d’Alzheimer. Revue Neurologique, 164, S96–S101.
Fang, C. W., Lin, C. H., Liu, Y. C., & Ou, Y. K. (2018). Differences in road-crossing decisions between healthy older adults and patients with Alzheimer’s disease. Journal of Safety Research, 66, 81–88. https://doi.org/10.1016/j.jsr.2018.06.003.
Finucane, M. L., & Lees, N. B. (2005). Decision-making competence of older adults: Models and methods. In Workshop on decision making needs of older adults, the National Academies.
Fournet, N., Mosca, C., & Moreaud, O. (2007). Déficits des processus inhibiteurs dans le vieillissement normal et la maladie d’Alzheimer. Psychologie et NeuroPsychiatrie du Vieillissement, 5, 14.
Gleichgerrcht, E., Ibáñez, A., Roca, M., Torralva, T., & Manes, F. (2010). Decision-making cognition in neurodegenerative diseases. Nature Reviews Neurology, 6(11), 611–623. https://doi.org/10.1038/nrneurol.2010.148.
Gorrie, C. A., Brown, J., & Waite, P. M. E. (2008). Crash characteristics of older pedestrian fatalities : Dementia pathology may be related to ‘at risk’ traffic situations. Accident Analysis & Prevention, 40(3), 912–919. https://doi.org/10.1016/j.aap.2007.10.006.
Grisso, T., Appelbaum, P. S., & Hill-Fotouhi, C. (1997). The MacCAT-T : A clinical tool to assess patients’ capacities to make treatment decisions. Psychiatric Services, 48(11), 1415–1419. https://doi.org/10.1176/ps.48.11.1415.
Ha, J., Kim, E. J., Lim, S., Shin, D. W., Kang, Y. J., Bae, S. M., et al. (2012). Altered risk-aversion and risk-taking behaviour in patients with Alzheimer’s disease. Psychogeriatrics, 12(3), 151–158.
Hamann, J., Bronner, K., Margull, J., Mendel, R., Diehl-Schmid, J., Bühner, M., et al. (2011). Patient Participation in Medical and Social Decisions in Alzheimer’s Disease. Journal of the American Geriatrics Society, 59(11), 2045–2052. https://doi.org/10.1111/j.1532-5415.2011.03661.x.
Henry, J. D., Ruffman, T., McDonald, S., O’Leary, M. A. P., Phillips, L. H., Brodaty, H., & Rendell, P. G. (2008). Recognition of disgust is selectively preserved in Alzheimer’s disease. Neuropsychologia, 46(5), 1363‑1370. https://doi.org/10.1016/j.neuropsychologia.2007.12.012
Hirschman, K. B., Joyce, C. M., James, B. D., Xie, S. X., & Karlawish, J. H. T. (2005). Do Alzheimer’s Disease Patients Want to Participate in a Treatment Decision, and Would Their Caregivers Let Them? The Gerontologist, 45(3), 381–388. https://doi.org/10.1093/geront/45.3.381.
Hot, P., Ramdeen, K. T., Borg, C., Bollon, T., & Couturier, P. (2014). Impaired Decision Making in Alzheimer’s Disease : A Deficit of Cognitive Strategy Selection? Clinical Psychological Science, 2(3), 328–335. https://doi.org/10.1177/2167702613504094.
Huettel, S. A., Stowe, C. J., Gordon, E. M., Warner, B. T., & Platt, M. L. (2006). Neural Signatures of Economic Preferences for Risk and Ambiguity. Neuron, 49(5), 765–775. https://doi.org/10.1016/j.neuron.2006.01.024.
Jacus, J. P., Bayard, S., Raffard, S., & Gély-Nargeot, M. C. (2012). Prise de décision dans le vieillissement normal et pathologique. Revue de Neuropsychologie, 5(2), 93. https://doi.org/10.3917/rne.052.0093.
Jacus, J. P., Gély-Nargeot, M. C., & Bayard, S. (2018). Ecological relevance of the Iowa gambling task in patients with Alzheimer’s disease and mild cognitive impairment. Revue Neurologique, 174(5), 327–336. https://doi.org/10.1016/j.neurol.2017.08.003.
Jasper, J. D., Bhattacharya, C., Levin, I. P., Jones, L., & Bossard, E. (2013). Numeracy as a Predictor of Adaptive Risky Decision Making : Numeracy and Risky Decision Making. Journal of Behavioral Decision Making, 26(2), 164–173. https://doi.org/10.1002/bdm.1748.
Karlawish, J. (2008). Measuring Decision-Making Capacity in Cognitively Impaired Individuals. Neurosignals, 16(1), 91–98. https://doi.org/10.1159/000109763.
Karlawish, J. H. T., Casarett, D. J., James, B. D., Bioethics, M., Xie, S. X., & Kim, S. Y. H. (2005). The ability of persons with Alzheimer disease (AD) to make a decision about taking an AD treatment. Neurology, 9(64), 1514–1519.
Kensinger, E. A., Shearer, D. K., Locascio, J. J., Growdon, J. H., & Corkin, S. (2003). Working memory in mild Alzheimer’s disease and early Parkinson’s disease. Neuropsychology, 17(2), 230–239. https://doi.org/10.1037/0894-4105.17.2.230.
Kim, S. Y. H., Karlawish, J. H. T., & Caine, E. D. (2002). Current State of Research on Decision-Making Competence of Cognitively Impaired Elderly Persons. The American Journal of Geriatric Psychiatry, 10(2), 151–165.
Kloeters, S., Bertoux, M., O’Callaghan, C., Hodges, J. R., & Hornberger, M. (2013). Money for nothing—Atrophy correlates of gambling decision making in behavioural variant frontotemporal dementia and Alzheimer’s disease. NeuroImage: Clinical, 2, 263‑272. https://doi.org/10.1016/j.nicl.2013.01.011
Lauriola, M., & Levin, I. P. (2001). Relating individual differences in Attitude toward Ambiguity to risky choices. Journal of Behavioral Decision Making, 14(2), 107–122. https://doi.org/10.1002/bdm.368.
Lerner, J. S., & Keltner, D. (2000). Beyond valence : Toward a model of emotion-specific influences on judgement and choice. Cognition & Emotion, 14(4), 473–493. https://doi.org/10.1080/026999300402763.
Lerner, J. S., Li, Y., Valdesolo, P., & Kassam, K. S. (2015). Emotion and Decision Making. Annual Review of Psychology, 66(1), 799–823. https://doi.org/10.1146/annurev-psych-010213-115043.
Levy, I., Snell, J., Nelson, A. J., Rustichini, A., & Glimcher, P. W. (2009). Neural Representation of Subjective Value Under Risk and Ambiguity. Journal of Neurophysiology, 103(2), 1036–1047. https://doi.org/10.1152/jn.00853.2009.
Levy, M. L., Cummings, J. L., Fairbanks, L. A., Masterman, D., Miller, B. L., Craig, A. H., et al. (1998). Apathy Is Not Depression. Journal of Neuropsychiatry, 10(3), 6.
Liebherr, M., Schiebener, J., Averbeck, H., & Brand, M. (2017). Decision Making under Ambiguity and Objective Risk in Higher Age – A Review on Cognitive and Emotional Contributions. Frontiers in Psychology, 8. https://doi.org/10.3389/fpsyg.2017.02128
Lim, H. K., Juh, R., Pae, C. U., Lee, B. T., Yoo, S. S., Ryu, S. H., et al. (2008). Altered Verbal Working Memory Process in Patients with Alzheimer’s Disease. Neuropsychobiology, 57(4), 181–187. https://doi.org/10.1159/000147471.
Lui, V. W. C., Lam, L. C. W., Chau, R. C. M., Fung, A. W. T., Wong, B. M. L., Leung, G. T. Y., et al. (2013). Structured Assessment of Mental Capacity to Make Financial Decisions in Chinese Older Persons With Mild Cognitive Impairment and Mild Alzheimer Disease. Journal of Geriatric Psychiatry and Neurology, 26(2), 69–77. https://doi.org/10.1177/0891988713481268.
Lui, V. W. C., Lam, L. C. W., Luk, D. N. Y., Wong, L. H. L., Tam, C. W. C., Chiu, H. F. K., & Appelbaum, P. S. (2009). Capacity to Make Treatment Decisions in Chinese Older Persons With Very Mild Dementia and Mild Alzheimer Disease. The American Journal of Geriatric Psychiatry, 17(5), 428–436. https://doi.org/10.1097/JGP.0b013e31819d3797.
Lui, V. W. C., Lam, L. C. W., Chau, R. C. M., Fung, A. W. T., Wong, B. M. L., Leung, G. T. Y., et al. (2012). Capacity to make decisions on medication management in Chinese older persons with mild cognitive impairment and mild Alzheimer’s disease. International Psychogeriatrics, 24(7), 1103.
Marson, D. C., Martin, R. C., Wadley, V., Griffith, H. R., Snyder, S., Goode, P. S., et al. (2009). Clinical Interview Assessment of Financial Capacity in Older Adults with Mild Cognitive Impairment and Alzheimer’s Disease. Journal of the American Geriatrics Society, 57(5), 806–814. https://doi.org/10.1111/j.1532-5415.2009.02202.x.
Mata, R., Josef, A. K., & Lemaire, P. (2015). Adaptive Decision Making and Aging. In Aging and Decision Making (p. 105‑126). Elsevier. https://doi.org/10.1016/B978-0-12-417148-0.00006-6
McCarrey, A. C., Henry, J. D., & Luszcz, M. (2010). Potential Mechanisms Contributing to Decision-Making Difficulties in Late Adulthood. Gerontology, 56(4), 430–434. https://doi.org/10.1159/000275060.
Miyake, A., Friedman, N. P., Emerson, M. J., Witzki, A. H., Howerter, A., & Wager, T. D. (2000). The Unity and Diversity of Executive Functions and Their Contributions to Complex “Frontal Lobe” Tasks : A Latent Variable Analysis. Cognitive Psychology, 41(1), 49–100. https://doi.org/10.1006/cogp.1999.0734.
Mueller, S. M., Arias, M. G., Mejuto Vázquez, G., Schiebener, J., Brand, M., & Wegmann, E. (2019). Decision support in patients with mild Alzheimer’s disease. Journal of Clinical and Experimental Neuropsychology, 41(5), 484–496.
Okonkwo, O. C., Wadley, V. G., Griffith, H. R., Belue, K., Lanza, S., Zamrini, E. Y., et al. (2008). Awareness of Deficits in Financial Abilities in Patients With Mild Cognitive Impairment : Going Beyond Self-Informant Discrepancy. The American Journal of Geriatric Psychiatry, 16(8), 650–659.
Pertl, M.-T., Benke, T., Zamarian, L., & Delazer, M. (2017). Effects of Healthy Aging and Mild Cognitive Impairment on a Real-Life Decision-Making Task. Journal of Alzheimer’s Disease, 58(4), 1077–1087. https://doi.org/10.3233/JAD-170119.
Rainville, C., Passini, R., & Marchand, N. (2001). A Multiple Case Study of Wayfinding in Dementia of the Alzheimer Type : Decision Making. Aging, Neuropsychology, and Cognition, 8(1), 54–71. https://doi.org/10.1076/anec.8.1.54.846.
Ready, R. E., Ott, B. R., Grace, J., & Cahn-Weiner, D. A. (2003). Apathy and Executive Dysfunction in Mild Cognitive Impairment and Alzheimer Disease. The American Journal of Geriatric Psychiatry, 11(2), 222–228. https://doi.org/10.1097/00019442-200303000-00013.
Rodgers, J. J., & Kass, J. S. (2018). Assessment of Medical Decision-making Capacity in Patients With Dementia. CONTINUUM: Lifelong Learning in Neurology, 24(3), 920–925. https://doi.org/10.1212/CON.0000000000000600.
Schiebener, J., & Brand, M. (2015). Decision Making Under Objective Risk Conditions–a Review of Cognitive and Emotional Correlates, Strategies, Feedback Processing, and External Influences. Neuropsychology Review, 25(2), 171–198. https://doi.org/10.1007/s11065-015-9285-x.
Schiebener, J., Wegmann, E., Pawlikowski, M., & Brand, M. (2012). Anchor effects in decision making can be reduced by the interaction between goal monitoring and the level of the decision maker’s executive functions. Cognitive Processing, 13(4), 321–332. https://doi.org/10.1007/s10339-012-0522-4.
Sinz, H., Zamarian, L., Benke, T., Wenning, G. K., & Delazer, M. (2008). Impact of ambiguity and risk on decision making in mild Alzheimer’s disease. Neuropsychologia, 46(7), 2043–2055. https://doi.org/10.1016/j.neuropsychologia.2008.02.002.
Slyer, J. T., Archibald, E., Moyo, F., & Truglio-Londrigan, M. (2018). Advance care planning and anticipatory decision making in patients with Alzheimer disease. The Nurse Practitioner, 6(43), 23–31.
Starkstein, S. E., Jorge, R., Mizrahi, R., & Robinson, R. G. (2006). A prospective longitudinal study of apathy in Alzheimer’s disease. Journal of Neurology, Neurosurgery and Psychiatry, 77(1).https://dx.doi.org.bibelec.univlyon2.fr/10.1136/jnnp.2005.069575
Stormoen, S., Almkvist, O., Eriksdotter, M., Sundström, E., & Tallberg, I.-M. (2014). Cognitive predictors of medical decision-making capacity in mild cognitive impairment and Alzheimer’s disease : Medical decision making in Alzheimer’s disease. International Journal of Geriatric Psychiatry, 29(12), 1304–1311. https://doi.org/10.1002/gps.4114.
Tallberg, I., Stormoen, S., Almkvist, O., Eriksdotter, M., & Sundström, E. (2013). Investigating medical decision-making capacity in patients with cognitive impairment using a protocol based on linguistic features. Scandinavian Journal of Psychology, 54(5), 386.
Thalén, L., Heimann Mühlenbock, K., Almkvist, O., Eriksdotter, M., Sundström, E., & Tallberg, I.-M. (2017). Do adapted vignettes improve medical decision-making capacity for individuals with Alzheimer’s disease? Scandinavian Journal of Psychology, 58(6), 497–503. https://doi.org/10.1111/sjop.12401.
Tonini, A., Dusart, L., & Ponchaux, F. (2016). Reconnaissance des émotions faciales et raisonnement social dans le vieillissement normal, le MCI et la maladie d’Alzheimer. NPG Neurologie - Psychiatrie - Gériatrie, 93(16), 171–176.
Torralva, T., Dorrego, F., Sabe, L., Chemerinski, E., & Starkstein, S. E. (2000). Impairments of Social Cognition and Decision Making in Alzheimer’s Disease. International Psychogeriatrics, 12(3), 359–368. https://doi.org/10.1017/S1041610200006463.
Uc, E. Y., Rizzo, M., Anderson, S. W., Shi, Q., & Dawson, J. D. (2004). Driver route-following and safety errors in early Alzheimer disease. Neurology, 63(5), 832–837. https://doi.org/10.1212/01.WNL.0000139301.01177.35.
van Duinkerken, E., Farme, J., Landeira-Fernandez, J., Dourado, M. C., Laks, J., & Mograbi, D. C. (2018). Medical and Research Consent Decision-Making Capacity in Patients with Alzheimer’s Disease : A Systematic Review. Journal of Alzheimer’s Disease, 65(3), 917–930. https://doi.org/10.3233/JAD-180311.
Vilarem, E., Armony, J. L., & Grèzes, J. (2019). Action opportunities modulate attention allocation under social threat. Emotion. https://doi.org/10.1037/emo0000598.
Viloria Jiménez, M. A., Chung Jaén, M., Vigara García, M., & Barahona-Alvarez, H. (2013). Decision-making in older people with dementia. Reviews in Clinical Gerontology, 23(4), 307–316. https://doi.org/10.1017/S0959259813000178.
Waltz, J. A., Knowlton, B. J., Holyoak, K. J., Boone, K. B., Back-Madruga, C., McPherson, S., et al. (2004). Relational Integration and Executive Function in Alzheimer’s Disease. Neuropsychology, 18(2), 296–305. https://doi.org/10.1037/0894-4105.18.2.296.
Werheid, K., Gruno, M., Kathmann, N., Fischer, H., Almkvist, O., & Winblad, B. (2010). Biased Recognition of Positive Faces in Aging and Amnestic Mild Cognitive Impairment., 25(1), 1.
Zamarian, L., Sinz, H., Bonatti, E., Gamboz, N., & Delazer, M. (2008). Normal aging affects decisions under ambiguity, but not decisions under risk. Neuropsychology, 22(5), 645–657. https://doi.org/10.1037/0894-4105.22.5.645.
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Gaubert, F., Chainay, H. Decision-Making Competence in Patients with Alzheimer’s Disease: A Review of the Literature. Neuropsychol Rev 31, 267–287 (2021). https://doi.org/10.1007/s11065-020-09472-2
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DOI: https://doi.org/10.1007/s11065-020-09472-2