Issue 8, 2021
From the journal:

Chemical Science

Chemical control of peptide material phase transitions†

Junjun Tan, ORCID logo ‡a   Li Zhang,‡a   Ming-Chien Hsieh,ab   Jay T. Goodwin, ORCID logo a   Martha A. Grover ORCID logo b  and  David G. Lynn ORCID logo *a  

* Corresponding authors

a Department of Chemistry and Biology, Emory University, Atlanta, Georgia 30322, USA
E-mail: dlynn2@emory.edu

b School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, USA

Abstract

Progressive solute-rich polymer phase transitions provide pathways for achieving ordered supramolecular assemblies. Intrinsically disordered protein domains specifically regulate information in biological networks via conformational ordering. Here we consider a molecular tagging strategy to control ordering transitions in polymeric materials and provide a proof-of-principle minimal peptide phase network captured with a dynamic chemical network.

Graphical abstract: Chemical control of peptide material phase transitions

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Article information

DOI
https://doi.org/10.1039/D0SC03666H
Article type
Edge Article
Submitted
02 Jul 2020
Accepted
05 Jan 2021
First published
07 Jan 2021
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY-NC license

Chem. Sci., 2021,12, 3025-3031

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Chemical control of peptide material phase transitions

J. Tan, L. Zhang, M. Hsieh, J. T. Goodwin, M. A. Grover and D. G. Lynn, Chem. Sci., 2021, 12, 3025 DOI: 10.1039/D0SC03666H

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