Original ArticleSubcutaneous transplantation of engineered islet/adipose-derived mesenchymal stem cell sheets in diabetic pigs with total pancreatectomy
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Keywords
Islet transplantation
Adipose-derived mesenchymal stem cells
Subcutaneous
Pig
Type 1 diabetes mellitus
Abbreviations
T1DM
Type 1 diabetes mellitus
IBMIR
instant blood-mediated inflammatory reaction
MSC
mesenchymal stem cell
ADSC
adipose-derived mesenchymal stem cell
PBS
phosphate-buffered saline
DMEM
Dulbecco's modified Eagle's medium
FBS
fetal bovine serum
UW
University of Wisconsin
MEM
minimum essential medium
IEQ
islet equivalent
H & E
hematoxylin and eosin
ELISA
enzyme-linked immunosorbent assay
CGM
continuous glucose monitor
IVGTT
intravenous glucose tolerance test
SD
standard deviation
TGF
transforming growth factor
HGF
hepatocyte growth factor
HSP32
heat shock protein 32
XIAP
X-linked inhibitor of apoptosis protein
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