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Novel Pyrimidines with Extended π-Conjugated Chains

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Abstract

The reactions of benzamidine, 4-methyl-, 4-iso-butoxy-, and 4-butoxybenzamidine hydrochlorides with chalcone and substituted chalcones in alcohol in the presence of KOH yielded 2,4,6-triarylpyrimidines. 4-Phenyl-2,6-bis(4-methylphenyl)pyrimidine and 1,3-bis(4-phenyl-6-{4-[(E)-styryl]phenyl]pyrimidin-2-yl}benzene) were reacted with (2-chlorophenyl)[(1E)-phenylmethylene]amine in the system KOH/LiH/DMF to give, respectively, 4-phenyl-2,6-bis{4-[(E)-styryl]phenyl}pyrimidine and 1,3-bis(4-phenyl-6-{4-[(E)-styryl]phenyl}pyrimidin-2-yl)benzene.

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Funding

The work was financially supported by the State Committee for Science of the Republic of Armenia through targeted funding (project no. 18T-1D249) and by the Ministry of Education and Science of the Russian Federation through a subsidy allocated for funding research at the Russian-Armenian University.

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Authors and Affiliations

  1. Russian–Armenian (Slavonic) University, 0051, Yerevan, Armenia

    A. A. Harutyunyan & G. G. Danagulyan

  2. Scientific Technological Center of Organic and Pharmaceutical Chemistry (STCOPHCH), National Academy of Sciences of Armenia, 0014, Yerevan, Armenia

    A. A. Harutyunyan, H. A. Panosyan & G. G. Danagulyan

Authors
  1. A. A. Harutyunyan
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  2. H. A. Panosyan
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  3. G. G. Danagulyan
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Correspondence to A. A. Harutyunyan.

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Harutyunyan, A.A., Panosyan, H.A. & Danagulyan, G.G. Novel Pyrimidines with Extended π-Conjugated Chains. Russ J Org Chem 56, 1952–1957 (2020). https://doi.org/10.1134/S1070428020110093

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  • DOI: https://doi.org/10.1134/S1070428020110093

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