An efficient image segmentation and classification of lung lesions in pet and CT image fusion using DTWT incorporated SVM

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Abstract

Automatic segmentation and classification of fused lung Computed Tomography (CT) and Positron Emission Tomography (PET) images is presented. This system consists of four basic stages: 1). Lung image fusion process; 2). Segmentation of fused lung CT/PET images; 3). Post pre-processing; 4). Classification of fused lung images. In the first step, the lung image fusion process is made by deep learning method. At first, the input CT/PET images are decomposed by Dual Tree m-band Wavelet Transform (DTWT). The coefficients of DTWT are fused by deep learning method. This fused image of CT/PET is the input for the following steps. In the next step, the fused CT/PET images are decomposed by DTWT. It produces lower and higher frequency sub-band coefficients. Then the lower frequency components are set to zero. Then higher frequency components are used for reconstruction. Then the clustering-based thresholding method is used for segmentation. In post pre-processing step, the unwanted small regions are removed by morphological operations. Then the lung region is detected. At last, in the classification step, the features are extracted by the intensity and texture-based features. These features are classified by hybrid classifiers like Support Vector Machine (SVM) are used. The performance of the system has a higher classification accuracy of 99% using SVM classifier.

Introduction

The uncontrollable division of cells in the lung region is known as lung cancer. Lung cancer causes the struggle in breathing. This growth of tumor can spread through the nearby regions and other body parts. The different type of lung cancers includes; non-small cell and small cell lung cancer. The symptoms of lung cancer include difficulty in breathing, pain in the chest, coughing with blood and weight loss. The lung cancer is mainly caused by smoking. The other causes include genetics, air pollution, asbestos and radon gas. Lung cancer is one of the leading causes of death. In India 2018, the mortality rate of lung cancer is 8.82%. To reduce the mortality rate, early diagnosis is required for lung cancer.

Section snippets

Literature survey

Classification of lesion margin in CT lung images for feature extraction is described by Riti et al. [1]. Initially, the CT lung images are preprocessed to obtain the Region Of Interest (ROI) area. Segmentation is made by Otsu's thresholding. Some unwanted areas which are obtained after segmentation are removed by connected component labeling. Then the features are extracted by compactness, convexity, circularity and solidity. Multi-Layer Perceptron (MLP) is used for classification.

Methods and materials

An efficient method for lung lesion segmentation and classification method using fused CT/PET images is discussed. Fig. 1 shows the overall workflow of classification and segmentation of CT and PET images. The workflow of this system is as follows: Initially, the CT and PET lung images are separately decomposed by DTWT. Then the coefficients of DTWT are used as input for the fusion process. The deep learning method is used for the fusion of CT/PET images. This fused image of CT/PET is the input

Results and discussion

The performance of fused CT/PET lung image classification and segmentation is discussed in this section. The CT/PET lung images are taken from the Reference Image Database to Evaluate therapy Response (RIDER) lung PET-CT database [29]. To order to reach an initial consensus on how to harmonize data collection and quantitative imaging research used to assessing reactions to drugs and radiation therapy, RIDER is a focused data collecting method. The work flow of segmentation and classification of

Conclusion

An efficient method for classification and segmentation of fused CT/PET lung image is presented. In this study, CNN is used for fusion of CT/PET lung images. The fused lung image is decomposed by DTWT, and the lower frequency components are set to zero. Then inverse transform is applied to reconstruct the image. The reconstructed lung image is used for FCM cluster-based thresholding technique. Morphological operation techniques are used for the removal of unwanted region and detection of a lung

Declaration of Competing Interest

1. All authors have participated in (a) conception and design, or analysis and interpretation of the data; (b) drafting the article or revising it critically for important intellectual content; and (c) approval of the final version.

2. This manuscript has not been submitted to, nor is under review at, another journal or other publishing venue.

3. The authors have no affiliation with any organization with a direct or indirect financial interest in the subject matter discussed in the manuscript.

4.

R. Mohana Priya has received her B.E. Degree in Electronics and Communication Engineering from University of Madras, Tamilnadu in 2004.M.E Degree in Applied Electronics from VMRF in 2010.She is pursuing her Ph.D in the field of Image Processing in Dept.of ECE from Sri Chandrasekharendra Saraswathi ViswaMahavidyalaya, Kanchipuram. Her research areas includes Image Processing, Signal Processing and Embedded Systems.She is life member of IETE since 2008.

References (32)

  • Q. Wang et al.

    Multiscale rotation-invariant convolutional neural networks for lung texture classification

    IEEE J. Biomed. Health Inform.

    (2017)
  • W. Zuo et al.

    Multi-resolution CNN and knowledge transfer for candidate classification in lung nodule detection

    IEEE Access

    (2019)
  • N. Emaminejad et al.

    Fusion of quantitative image and genomic biomarkers to improve prognosis assessment of early stage lung cancer patients

    IEEE Trans. Biomed. Eng.

    (2015)
  • S. Qiu et al.

    Lung nodules detection in CT images using Gestalt-based algorithm

    Chin. J. Electron.

    (2016)
  • S. Potghan et al.

    Multi-layer perceptron based lung tumor classification

  • R. Manickavasagam et al.

    GACM based segmentation method for Lung nodule detection and classification of stages using CT images

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    R. Mohana Priya has received her B.E. Degree in Electronics and Communication Engineering from University of Madras, Tamilnadu in 2004.M.E Degree in Applied Electronics from VMRF in 2010.She is pursuing her Ph.D in the field of Image Processing in Dept.of ECE from Sri Chandrasekharendra Saraswathi ViswaMahavidyalaya, Kanchipuram. Her research areas includes Image Processing, Signal Processing and Embedded Systems.She is life member of IETE since 2008.

    DR. P. Venkatesan, B.E.,(ECE).,ME-Power Electronics & drives, PhD, Associate Professor, Department of Electronics Communication Eenginering, Sri Chandrasekharendra Saraswathi Viswamahavidyalaya, Kanchipuram. His Area Of Interest Lies In Signal Processing, Digital Image Processing, Embedded Systems, Neural Networks. He has a more than 20 year of teaching and research experience.He has participated in International and national conferences. He has a good number of publications in reputed journals. He has guided many Ph.D Scholars and also guiding many good numbers of Ph.D scholars

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