Abstract
Periodic chemical cleaning with sodium hypochlorite (NaClO) is essential to restore the membrane permeability in a membrane bioreactor (MBR). However, the chlorination of membrane foulants results in the formation of disinfection by-products (DBPs), which will cause the deterioration of the MBR effluent and increase the antibiotic resistance in bacteria in the MBR tank. In this study, the formation of 14 DBPs during chemical cleaning offouled MBR membrane modules was investigated. Together with the effects of biofilm extracellular polymeric substances (EPS), influences of reaction time, NaClO dosage, initial pH, and cleaning temperature on the DBP formation were investigated. Haloacetic acids (HAAs) and trichloromethane (TCM), composed over 90% of the DBPs, were increasingly accumulated as the NaClO cleaning time extended. By increasing the chlorine dosage, temperature, and pH, the yield of TCM and dichloroacetic acid (DCAA) was increased by up to a factor of 1–14, whereas the yields of haloacetonitriles (HANs) and haloketones (HKs) were decreased. Either decreasing in the chlorine dosage and cleaning temperature or adjusting the pH of cleaning reagents toward acidic or alkaline could effectively reduce the toxic risks caused by DBPs. After the EPS extraction pretreatment, the formation of DBPs was accelerated in the first 12 h due to the damage of biofilm structure. Confocal laser scanning microscopy (CLSM) images showed that EPS, particularly polysaccharides, were highly resistant to chlorine and might be able to protect the cells exposed to chlorination.
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Alasonati E, Slaveykova VI (2012). Effects of extraction methods on the composition and molar mass distributions of exopolymeric substances of the bacterium Sinorhizobium meliloti. Bioresource Technology, 114: 603–609
Berry D, Holder D, Xi C, Raskin L (2010). Comparative transcriptomics of the response of Escherichia coli to the disinfectant monochloramine and to growth conditions inducing monochloramine resistance. Water Research, 44(17): 4924–4931
Cai W, Han J, Zhang X, Liu Y (2020). Formation mechanisms of emerging organic contaminants during on-line membrane cleaning with NaOCl in MBR. Journal of Hazardous Materials, 386: 121966
Cai W, Liu J, Zhu X, Zhang X, Liu Y (2017). Fate of dissolved organic matter and byproducts generated from on-line chemical cleaning with sodium hypochlorite in MBR. Chemical Engineering Journal, 323: 233–242
Chen B (2011). Hydrolytic stabilities of halogenated disinfection byproducts: Review and rate constant quantitative structure-property relationship analysis. Environmental Engineering Science, 28(6): 385–394
Chowdhury S, Champagne P, James Mclellan P (2010). Investigating effects of bromide ions on trihalomethanes and developing model for predicting bromodichloromethane in drinking water. Water Research, 44(7): 2349–2359
Chu W, Gao N, Krasner S W, Templeton M R, Yin D (2012). Formation of halogenated C-, N-DBPs from chlor(am)ination and UV irradiation of tyrosine in drinking water. Environmental Pollution, 161: 8–14
Chu W, Li X, Bond T, Gao N, Bin X, Wang Q, Ding S (2016). Copper increases reductive dehalogenation of haloacetamides by zero-valent iron in drinking water: Reduction efficiency and integrated toxicity risk. Water Research, 107: 141–150
Chu W H, Gao N Y, Deng Y, Dong B Z (2009). Formation of chloroform during chlorination of alanine in drinking water. Chemosphere, 77(10): 1346–1351
Ding A, Zhao Y, Ngo H H, Bai L, Li G, Liang H, Ren N, Nan J (2020a). Metabolic uncoupler, 3,3’,4’,5-tetrachlorosalicylanilide addition for sludge reduction and fouling control in a gravity-driven membrane bioreactor. Frontiers of Environmental Science & Engineering, 14(6): 96
Ding A, Zhao Y, Yan Z, Bai L, Yang H, Liang H, Li G, Ren N (2020b). Co-application of energy uncoupling and ultrafiltration in sludge treatment: Evaluations of sludge reduction, supernatant recovery and membrane fouling control. Frontiers of Environmental Science & Engineering, 14(4): 59
Fang J, Ma J, Yang X, Shang C (2010). Formation of carbonaceous and nitrogenous disinfection by-products from the chlorination of Microcystis aeruginosa. Water Research, 44(6): 1934–1940
Garrido-Baserba M, Asvapathanagul P, Mccarthy G W, Gocke T E, Olson B H, Park H D, Al-Omari A, Murthy S, Bott C B, Wett B, Smeraldi J D, Shaw A R, Rosso D (2016). Linking biofilm growth to fouling and aeration performance of fine-pore diffuser in activated sludge. Water Research, 90: 317–328
Gordon C A, Hodges N A, Marriott C (1988). Antibiotic interaction and diffusion through alginate and exopolysaccharide of cystic fibrosis-derived Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy, 22(5): 667–674
Guo X, Li C, Li C, Wei T, Tong L, Shao H, Zhou Q, Wang L, Liao Y (2019). G-CNTs/PVDF mixed matrix membranes with improved antifouling properties and filtration performance. Frontiers of Environmental Science & Engineering, 13(6): 81
Joo S H, Mitch W A (2007). Nitrile, aldehyde, and halonitroalkane formation during chlorination/chloramination of primary amines. Environmental Science & Technology, 41(4): 1288–1296
Luong T V, Peters C J, Perry R (1982). Influence of bromide and ammonia upon the formation of trihalomethanes under water-treatment conditions. Environmental Science & Technology, 16(8): 473–479
Lv L, Jiang T, Zhang S, Yu X (2014). Exposure to mutagenic disinfection byproducts leads to increase of antibiotic resistance in Pseudomonas aeruginosa. Environmental Science & Technology, 48 (14): 8188–8195
Ma D, Gao B, Wang Y, Yue Q, Li Q (2015). Factors affecting trihalomethane formation and speciation during chlorination of reclaimed water. Water Science and Technology, 72(4): 616–622
Nikolaou A D, Golfinopoulos S K, Kostopoulou M N, Lekkas T D (2000). Decomposition of dihaloacetonitriles in water solutions and fortified drinking water samples. Chemosphere, 41(8): 1149–1154
Pellicer-Nàcher C, Domingo-Félez C, Mutlu A G, Smets B F (2013). Critical assessment of extracellular polymeric substances extraction methods from mixed culture biomass. Water Research, 47(15): 5564–5574
Plewa, M J, Wagner E D. Charting a new path to resolve the adverse health effects of DBPs (2015). In: Karanfil T, Mitch B, Westerhoff B, Xie Y F. Recent advances in disinfection by-products. Washington, DC: American Chemical Society, 1190: 3–23
Sirivedhin T, Gray K A (2005). 2. Comparison of the disinfection by-product formation potentials between a wastewater effluent and surface waters. Water Research, 39(6): 1025–1036
Sun H, Liu H, Han J, Zhang X, Cheng F, Liu Y (2018). Chemical cleaning-associated generation of dissolved organic matter and halogenated byproducts in ceramic MBR: Ozone versus hypochlorite. Water Research, 140: 243–250
Wang H, Shi W, Ma D, Shang Y, Wang Y, Gao B (2020a). Formation of DBPs during chlorination of antibiotics and control with permanganate/bisulfite pretreatment. Chemical Engineering Journal, 392: 123701
Wang S, Chew J W, Liu Y (2020b). An environmentally sustainable approach for online chemical cleaning of MBR with activated peroxymonosulfate. Journal of Membrane Science, 600: 117872
Wang Z, Ding J, Xie P, Chen Y, Wan Y, Wang S (2018). Formation of halogenated by-products during chemical cleaning of humic acid-fouled UF membrane by sodium hypochlorite solution. Chemical Engineering Journal, 332: 76–84
Wang Z, Ma J, Tang C Y, Kimura K, Wang Q, Han X (2014). Membrane cleaning in membrane bioreactors: A review. Journal of Membrane Science, 468: 276–307
Wu Q, Yan Y, Lu Y, Du Y, Liang Z, Hu H (2020). Identification of important precursors and theoretical toxicity evaluation of byproducts driving cytotoxicity and genotoxicity in chlorination. Frontiers of Environmental Science & Engineering, 14(2): 25
Xiao K, Xu Y, Liang S, Lei T, Sun J, Wen X, Zhang H, Chen C, Huang X (2014). Engineering application of membrane bioreactor for wastewater treatment in China: Current state and future prospect. Frontiers of Environmental Science & Engineering, 8(6): 805–819
Xie P, De Lannoy C F, Ma J, Wiesner M R (2015). Chlorination of polyvinyl pyrrolidone-polysulfone membranes: Organic compound release, byproduct formation, and changes in membrane properties. Journal of Membrane Science, 489: 28–35
Xue Z, Sendamangalam V R, Gruden C L, Seo Y (2012). Multiple roles of extracellular polymeric substances on resistance of biofilm and detached clusters. Environmental Science & Technology, 46(24): 13212–13219
Yang X, Shang C, Westerhoff P (2007). Factors affecting formation of haloacetonitriles, haloketones, chloropicrin and cyanogen halides during chloramination. Water Research, 41(6): 1193–1200
Yu Y, Reckhow D A (2015). Kinetic analysis of haloacetonitrile stability in drinking waters. Environmental Science & Technology, 49(18): 11028–11036
Yuan B, Wang X, Tang C, Li X, Yu G (2015). In situ observation of the growth of biofouling layer in osmotic membrane bioreactors by multiple fluorescence labeling and confocal laser scanning microscopy. Water Research, 75: 188–200
Zhang X, Liu Y (2020). Potential toxicity and implication of halogenated byproducts generated in MBR online — cleaning with hypochlorite. Journal of Chemical Technology and Biotechnology (Oxford, Oxfordshire), 95(1): 20–26
Zhu X, Zhang X (2016). Modeling the formation of TOCl, TOBr and TOI during chlor(am)ination of drinking water. Water Research, 96: 166–176
Acknowledgements
This work was supported by the National Natural Science Foundation of China (Grant No. 51808316) and the Natural Science Foundation of Shandong Province (Grant No. ZR2019BEE015). In addition, we thank Xiaomin Zhao, Haiyan Yu, and Sen Wang from the State Key Laboratory of Microbial Technology for assistance with confocal imaging.
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Highlights
• HAAs was dominant among the DBPs of interest.
• Rising time, dose, temperature and pH raised TCM and HAAs but reduced HANs and HKs.
• Low time, dose and temperature and non-neutrality pH reduced toxic risks of DBPs.
• The presence of EPS decelerated the production of DBPs.
• EPS, particularly polysaccharides were highly resistant to chlorine.
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Wang, H., Ma, D., Shi, W. et al. Formation of disinfection by-products during sodium hypochlorite cleaning of fouled membranes from membrane bioreactors. Front. Environ. Sci. Eng. 15, 102 (2021). https://doi.org/10.1007/s11783-021-1389-3
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DOI: https://doi.org/10.1007/s11783-021-1389-3