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Good pyridine hunting: a biomimic compound, a modifier and a unique pharmacophore in agrochemicals

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Chemistry of Heterocyclic Compounds Aims and scope

95 agrochemical products have been described based on the pyridine scaffold making it the most commercially successful heterocycle in the synthesis of plant protection chemicals in the 21st century. The pyridine fragment is capable of modifying the properties of compounds, sometimes changing their application, and can be a unique pharmacophore. When possible, the relationship of pyridine analogs with carbocyclic or aliphatic precursors is shown. The mechanism of action of the compounds is described, if known. Examples of syntheses of pyridine intermediates used in the manufacture of agrochemicals are given.

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    Vladimir V. Zakharychev & Aleksandr V. Kuzenkov

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  3. Andrey M. Martsynkevich
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Correspondence to Vladimir V. Zakharychev.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2020, 56(12), 1491–1516

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Zakharychev, V.V., Kuzenkov, A.V. & Martsynkevich, A.M. Good pyridine hunting: a biomimic compound, a modifier and a unique pharmacophore in agrochemicals. Chem Heterocycl Comp 56, 1491–1516 (2020). https://doi.org/10.1007/s10593-020-02843-w

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  • DOI: https://doi.org/10.1007/s10593-020-02843-w

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