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Novel multicomponent synthesis of 6,7-dihydro-5H-cyclopenta[b]pyridine derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

The multicomponent condensation of malononitrile, hydrogen sulfide, aldehydes, 1-(cyclopent-1-en-1-yl)pyrrolidine, and alkylating agents leads to the formation of 6,7-dihydro-5H-cyclopenta[b]pyridine derivatives. The structure of a number of heterocycles obtained on their basis was studied by X-ray structural analysis.

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This study was carried out with the financial support of the Ministry of Science and Higher Education of the Russian Federation (project FSSF-2020-0017).

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Authors and Affiliations

  1. Luhansk Taras Shevchenko National University, 2 Oboronna St, Luhansk, 91011, Ukraine

    Ivan V. Dyachenko & Vladimir D. Dyachenko

  2. National Research Center “Kurchatov Institute”, 1 Akademika Kurchatova Sq, Moscow, 123182, Russia

    Pavel V. Dorovatovskii

  3. RUDN University, 6 Miklukho-Maklaya St, Moscow, 117198, Russia

    Victor N. Khrustalev

  4. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave, Moscow, 119991, Russia

    Victor N. Khrustalev

  5. Lomonosov Moscow State University, 1, Build. 3 Leninskie Gory, Moscow, 119991, Russia

    Valentine G. Nenajdenko

Authors
  1. Ivan V. Dyachenko
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  2. Vladimir D. Dyachenko
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  3. Pavel V. Dorovatovskii
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  4. Victor N. Khrustalev
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  5. Valentine G. Nenajdenko
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Corresponding author

Correspondence to Valentine G. Nenajdenko.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2020, 56(12), 1592–1598

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Dyachenko, I.V., Dyachenko, V.D., Dorovatovskii, P.V. et al. Novel multicomponent synthesis of 6,7-dihydro-5H-cyclopenta[b]pyridine derivatives. Chem Heterocycl Comp 56, 1592–1598 (2020). https://doi.org/10.1007/s10593-020-02854-7

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  • DOI: https://doi.org/10.1007/s10593-020-02854-7

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