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Traditional use of medicinal plants in Jablanica district (South-Eastern Serbia): ethnobotanical survey and comparison with scientific data

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Abstract

Ethnobotanical survey presents the first step in the identification of new bioactive compounds. This study aimed to collect, document and analyse data on the traditional use of medicinal plants in Jablanica district (South-Eastern Serbia) and to compare traditional knowledge with scientifically proven data. Ethnobotanical study was carried out using semi-structured interviews with 103 informants. Discussion of the results was performed after the quantitative ethnobotany factors were calculated. Comparison of the data was done with those of European Medicines Agency (EMA), Yugoslav Pharmacopoeia 1984 (Ph. Jug. IV) and relevant scientific papers. The informants reported data on 89 medicinal plants belonging to 49 families in Jablanica district. The dominantly used families were Lamiaceae and Asteraceae, while Hypericum perforatum L., Mentha × piperita L. and Matricaria chamomilla L. were the species with the highest number of use reports. The most frequently reported indications were respiratory, gastrointestinal, dermatologic, and psychological diseases. The species with most diverse uses were Taraxacum campylodes G.E.Haglund, Achillea millefolium L. and Rosa canina L. According to our results, medicinal plants in Jablanica district are mainly used for treating minor health issues as a mode of primary health care. The wide application of species belonging to Lamiaceae and Asteraceae families can be partially attributed to the fact that many cosmopolitan medicinal plant species belongs to these families and also to their predominance in the flora of Jablanica districts.

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References

  • Antonova M, Wienecke T, Olesen J, Ashina M (2013) Prostaglandin E2 induces immediate migraine-like attack in migraine patients without aura. J Headache Pain 14(Suppl 1):P113. https://doi.org/10.1186/1129-2377-14-S1-P113

    Article  PubMed Central  Google Scholar 

  • Araujo CM, Lucio Kde P, Silva ME, Isoldi MC, De Souza GH, Brandao GC, Schulz R, Costa DC (2015) Morus nigra leaf extract improves glycemic response and redox profile in the liver of diabetic rats. Food Funct. 6:3490–3499. https://doi.org/10.1039/c5fo00474h

    Article  CAS  PubMed  Google Scholar 

  • Avramović, D., Zlatković, B., Ranđelović, N. (2005): Protected area of nature in southeastern Serbia. In: Proceeding of the 8th symposium on the flora of Southeastern Serbia and Neighboring regions, Niš, pp 223–227

  • Buenz EJ, Verpoorte R, Bauer BA (2018) The ethnopharmacological contribution to bioprospecting natural products. Annu Rev Pharmacol 58:509–530. https://doi.org/10.1146/annurev-pharmtox-010617-052703

    Article  CAS  Google Scholar 

  • Cavero RY, Akerreta S, Calvo MI (2011) Pharmaceutical ethnobotany in the Middle Navarra (Iberian Peninsula). J Ethnopharmacol 137:844–855. https://doi.org/10.1016/j.jep.2011.07.001

    Article  CAS  PubMed  Google Scholar 

  • Chávez-Silva F, Cerón-Romero L, Arias-Durán L, Navarrete-Vázquez G, Almanza-Pérez J, Román-Ramos R, Ramírez-Ávila G, Perea-Arango I, Villalobos-Molina R, Estrada-Soto S (2018) Antidiabetic effect of Achillea millefollium through multitarget interactions: α-glucosidases inhibition, insulin sensitization and insulin secretagogue activities. J Ethnopharmacol 212:1–7. https://doi.org/10.1016/j.jep.2017.10.005

    Article  PubMed  Google Scholar 

  • Dajić-Stevanović Z, Petrović M, Aćić S (2014) Ethnobotanical knowledge and traditional use of plants in Serbia in relation to sustainable rural development. In: Pieroni A, Quave CL (eds) Ethnobotany and biocultural ddiversities in the Balkans. Springer, New York, pp 229–252

    Google Scholar 

  • European Medicines Agency (EMA): http://www.ema.eu. Accessed 27 Aug 2019

  • Freysdottir F, Logadottir OT, Omarsdottir SS, Vikingsson A, Hardardottir I (2016) A polysaccharide fraction from Achillea millefolium increases cytokine secretion and reduces activation of Akt, ERK and NF-κB in THP-1 monocytes. Carbohydr Polym 143:131–138. https://doi.org/10.1016/j.carbpol.2016.02.017

    Article  CAS  PubMed  Google Scholar 

  • International Classification of Primary Care (ICPC): http://www.kith.no/upload/2705/ICPC-2-English.pdf. Accessed 20 Jan 2018

  • Jarić S, Popović Z, Mačukanović-Jocić M, Đurđević L, Mijatović M, Kradžič B, Mitrović M, Pavlović P (2007) An ethnobotanical study on the usage of wild medicinal herbs from Kopaonik Mountain (Central Serbia). J Ethnopharmacol 111:160–175. https://doi.org/10.1016/j.jep.2006.11.007

    Article  PubMed  Google Scholar 

  • Jarić S, Mitrović M, Pavlović P (2014) An ethnobotanical and ethnomedicinal study on the use of wild medicinal plants in rural areas of Serbia. In: Pieroni A, Quave CL (eds) Ethnobotany and biocultural diversities in the Balkans. Springer, New York, pp 87–112

    Google Scholar 

  • Jarić S, Mačukanović-Jocić M, Đurđević L, Mitrović M, Kostić O, Karadžić B, Pavlović P (2015) An ethnobotanical survey of traditionally used plants on Suva planina mountain (south-eastern Serbia). J Ethnopharmacol 175:93–108. https://doi.org/10.1016/j.jep.2015.09.002

    Article  PubMed  Google Scholar 

  • Jarić S, Kostić O, Mataruga Z, Pavlović D, Pavlović M, Mitrović M, Pavlović P (2018) Traditional wound-healing plants used in the Balkan region (Southeast Europe). J Ethnopharmacol 211:311–328. https://doi.org/10.1016/j.jep.2017.09.018

    Article  PubMed  Google Scholar 

  • Josifović M (1970–1977) Flora of Serbia, I–IX (in Serbian: Serbian Academy of Sciences and Art, Belgrade)

  • Katić R (1980) The Chilandar Medical Codex (in Serbian: Narodna biblioteka Srbije; Republički zavod za međunarodnu naučnu, prosvetnu, kulturnu i tehničku saradnju; Dečije novine)

  • Laakmann E, Grajecki D, Doege K, Eulenburg C, Buhling KJ (2012) Efficacy of Cimicifuga racemosa, Hypericum perforatum and Agnus castus in the treatment of climacteric complaints: a systematic review. Gynecol Endocrinol 28(9):703–709. https://doi.org/10.3109/09513590.2011.650772

    Article  PubMed  Google Scholar 

  • Lee HG, Kim H, Oh WK, Yu KA, Choe YK, Ahn JS, Kim DS, Kim SH, Dinarello CA, Kim K, Yoon DY (2004) Tetramethoxy hydroxyflavone p7F downregulates inflammatory mediators via the inhibition of nuclear factor kappa B. Ann NY Acad Sci 1030:555–568. https://doi.org/10.1196/annals.1329.065

    Article  CAS  PubMed  Google Scholar 

  • Mahboubi M (2018) Mentha spicata L. essential oil, phytochemistry and its effectiveness in flatulence. J Tradit Complement Med. https://doi.org/10.1016/j.jtcme.2017.08.011

    Article  Google Scholar 

  • Marmol I, Sanzhez-de-Diego C, Jimenez-Moreno N, Anan-Azpilicueta C, Rodriguez-Yoldi MJ (2017) Therapeutic applications of rose hips from different Rosa species. Int J Mol Sci 18(1837):1–37. https://doi.org/10.3390/ijms18061137

    Article  CAS  Google Scholar 

  • Menković N, Šavikin K, Tasić S, Zdunić G, Stešević D, Milosavljević S, Vincek D (2011) Ethnobotanical study on traditional uses of wild medicinal plants in Prokletije Mountains (Montenegro). J Ethnopharmacol 133:97–107. https://doi.org/10.1016/j.jep.2010.09.008

    Article  PubMed  Google Scholar 

  • Mustafa B, Hajdari A, Pajazita Q, Syla A, Quave CL, Pieroni A (2012) An ethnobotanical survey of the Gollak region, Kosovo. Genet Resour Crop Evol 59:739–754. https://doi.org/10.1007/s10722-011-9715-4

    Article  Google Scholar 

  • Ph. Jug. IV (1984) Yugoslav Pharmacopoeia IV, Savezni zavod za zdravstvenu zastitu, Beogread (in Serbian)

  • Phillips O, Gentry AH (1993) The useful plants of Tambopata, Peru: I. Statistical hypothesis tests with a new quantitative technique. Econom Bot 47:15–32

    Article  Google Scholar 

  • Pieroni A, Giusti ME, Quave CL (2011) Cross-Cultural Ethnobiology in the Western Balkans: medical Ethnobotany and Ethnozoology among Albanians and Serbs in the Pešter Plateau, Sandžak, South-Western Serbia. Hum Ecol 39:333–349. https://doi.org/10.1007/s10745-011-9401-3

    Article  Google Scholar 

  • Quave CL, Pieroni A (2015) A reservoir of ethnobotanical knowledge informs resilient food security and health strategies in the Balkans. Nat Plants 1: article number 14021. https://doi.org/10.1038/nplants.2014.21

  • Ranđelović V, Zlatković B, Jušković M (2005) Diverzitet flore jugoistočne Srbije. In: 10th Symposium on the Flora of Southeastern Serbia and Neighboring Regions, Proceedings, Niš, 18 (in Serbian)

  • Redžić S (2007) The ecological aspect of ethnobotany and ethnopharmacology of population in bosnia and herzegovina. Coll Antropol 31:869–890

    PubMed  Google Scholar 

  • Reyes-Garcia V, Huanca T, Vadez V, Leonard W, Wilkie D (2006) Cultural, practical, and economic value of wild plants: a quantitative study in the Bolivian Amazon. Econom Bot 60(1):62–74

    Article  Google Scholar 

  • Sarić M (1989) Medicinal plants of the Federal Republic of Serbia. SASA, special edition, book 65, Belgrad (in Serbian)

  • Sarić M, Diklić N (1986) Flora of Serbia, X (in Serbian: Serbian Academy of Sciences and Art, Belgrade)

  • Šavikin K, Zdunić G, Menković N, Živković J, Ćujić N, Tereščenko M, Bigović D (2013) Ethnobotanical study on traditional use of medicinal plants in South-Western Serbia, Zlatibor district. J Ethnopharmacol 146:803–810. https://doi.org/10.1016/j.jep.2013.02.006

    Article  PubMed  Google Scholar 

  • Serbia: Brief health system review, 2014. http://www.hpi.sk/en/2014/01/serbia-brief-health-system-review/. Accessed 23 Sept 2020

  • Serbian Medicines Agency (2016) https://2016.export.gov/industry/health/healthcareresourceguide/eg_main_108616.asp

  • Sharifi F, Simbar M, Mojab F, Majd HA (2014) Comparison of the effects of Matricaria chamomila (Chamomile) extract and mefenamic acid on the intensity of premenstrual syndrome. Complement Ther Clin Pract 20(1):81–88. https://doi.org/10.1016/j.ctcp.2013.09.002

    Article  PubMed  Google Scholar 

  • Srithi K, Balslev H, Wangpakapattanawong P, Srisanga P, Trisonthi C (2009) Medicinal plant knowledge and its erosion among thr Mien (Yao) in northern Thailand. J Ethnopharmacol 123(2):335–342. https://doi.org/10.1016/j.jep.2009.02.035

    Article  PubMed  Google Scholar 

  • Stevanović V, Jovanović S, Lakušić D, Niketić M (1995) The diversity of the vascular flora of Yugoslavia with a review of species of international significance. In: Stevanović V, Vasić V (eds) The biodiversity of Yugoslavia with a review of species of international significance. Faculty of Biology and Ecolibri, Belgrade, pp 183–219

    Google Scholar 

  • Stojković D, Barros L, Petrović J, Glamočlija J, Santos-Buelga C, Ferreira ICFR, Soković M (2015) Ethnopharmacological uses of Sempervivum tectorum L. in Southern Serbia: scientific confirmation for the use against otitis linked bacteria. J Ethnopharmacol 176:297–304. https://doi.org/10.1016/j.jep.2015.11.014

    Article  PubMed  Google Scholar 

  • Teklehaymanot T, Giday M (2007) Ethnobotanical study of medicinal plants used by people in Zegie Peninsula, Northwestern Ethiopia. J Ethnobiol Ethnomed 3: art. no. 12. https://doi.org/10.1186/1746-4269-3-12

  • Tomović, G., Stevanović, V. (2010): Balkanski endemiti u flori jugoistočne i južne Srbije. In: 10th Symposium on the Flora of Southeastern Serbia and Neighboring Regions, Proceedings, Niš, pp 12–13 (in Serbian)

  • Trotter RT, Logan MH (1986) Informant consensus: a new approach for identifying potentially effective medicinal plants. In: Etkin NL (ed) Plants in indigenous medicine and diet, behavioural approaches. Redgrave Publishing Company, New York, pp 91–112

    Google Scholar 

  • Tucakov J (1997) Lecenje biljem. Rad, Belgrade in Serbian

    Google Scholar 

  • Tutin TG, Heywood V, Burges NA, Moore DM, Valentine DH, Walters SM et al (1964–1980). Flora Europaea 1–5. Cambridge University Press, Cambridge

  • Tutin TG, Heywood V, Burges NA, Moore DM, Valentine DH, Walters SM et al (1993) Flora Europaea 1, 2nd edn. Cambridge Univeristy Press, Cambridge

    Google Scholar 

  • Venancio AM, Onofre ASC, Lira AF, Alves PB, Blank AF, Antoniolli AR, Marchioro M, Dos Santos EC, Santos de Arujo B (2011) Chemical composition, acute toxicity and antinociceptive activity of the essential oil of a plant breeding cultivar of Basil (Ocimum basilicum L.). Planta Med 77:825–829. https://doi.org/10.1055/s-0030-1250607

    Article  CAS  PubMed  Google Scholar 

  • World Health Organization (2013) WHO Traditional Medicine Strategy 2014-2023. https://apps.who.int/iris/bitstream/handle/10665/92455/9789241506090_eng.pdf;jsessionid=D92DA94B7A947C8B3249B838E61E138F?sequence=1. Accessed 14 Aug 2020

  • Zlatković BK, Bogosavljević SS, Radivojević AR, Pavlović AM (2014) Traditional use of the native medicinal plant resource of Mt. Rtanj (Eastern Serbia): ethnobotanical evaluation and comparison. J Ethnopharmacol 151:704–713. https://doi.org/10.1016/j.jep.2013.11.037

    Article  PubMed  Google Scholar 

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Acknowledgements

This work has been supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia (451-03-68/2020-14/200003).

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Authors and Affiliations

  1. Institute for Medicinal Plants Research “Dr. Josif Pančić”, Tadeuša Košćuška 1, Belgrade, 11000, Serbia

    Jelena Živković, Gordana Zdunić, Nebojša Menković & Katarina Šavikin

  2. Department of Pharmacognosy, Faculty of Pharmacy Novi Sad, University Bussines Academy in Novi Sad, Trg mladenaca 5, Novi Sad, Serbia

    Milan Ilić & Nataša Jovanović-Lješković

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  1. Jelena Živković
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  2. Milan Ilić
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Correspondence to Jelena Živković.

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Živković, J., Ilić, M., Zdunić, G. et al. Traditional use of medicinal plants in Jablanica district (South-Eastern Serbia): ethnobotanical survey and comparison with scientific data. Genet Resour Crop Evol 68, 1655–1674 (2021). https://doi.org/10.1007/s10722-020-01094-0

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