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Modular design of paper based switches for autonomous lab-on paper micro devices

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Abstract

This paper presents a new approach towards the design of paper based autonomous microfluidic devices. Autonomy in the device operation is achieved through the incorporation of mechanically actuated microfluidic switches that are versatile in their design and may be configured to be simple time triggered ON or OFF switches or more complex switches that can be timed to be in multiple states (timed ON, followed by timed OFF). These switches are self-contained and require no external power for their operation, deriving their functionality solely through stored elastic energy. This paper presents the design and fabrication of these switches as fluidic analogs of electronic transistors, and their integration into microfluidic paper based circuit demonstrating their operation as a programmable paper-based microfluidic device.

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Acknowledgements

The authors would like to thank D Boland and H Eom from the department of Biochemistry – Dr. Horn’s research group for help with the performance of the ALP assay. The authors gratefully acknowledge support from Northern Illinois Universities Research and Artistry fund for this project.

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Correspondence to Venumadhav Korampally.

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Patil, Y., Dotseth, K., Shapiro, T. et al. Modular design of paper based switches for autonomous lab-on paper micro devices. Biomed Microdevices 23, 1 (2021). https://doi.org/10.1007/s10544-020-00537-w

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  • DOI: https://doi.org/10.1007/s10544-020-00537-w

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