Skip to main content

Advertisement

SpringerLink
Log in

RETRACTED ARTICLE: Two Mixed Ligand Coordination Polymers: Selective Detection of TNP and Protective Effect on Alzheimer’s Disease by Stimulating Cell Autophagy

  • Original Paper
  • Published:
Journal of Cluster Science Aims and scope Submit manuscript

This article was retracted on 01 February 2024

This article has been updated

Abstract

By employment of a flexible benzoimidazole-type ligand of 1-(2-(1H-benzoimidazol-1-yl)ethyl)-1H-benzoimidazole (beb), two coordination polymers (CPs) of Zn(II) and Co(II) namely, {[Co(beb)(dmglut)]}n (1) and {Zn2(beb)2(hipt)2(H2O)1.5(MeOH)}]n (2) have been produced in the existence of distinct dicarboxylate ligands and metal ions. The measurements of luminescence reveal that the Zn(II)-containing complex 2 can determine 2,4,6-trinitrophenol (TNP) in DMF which possesses high selectivity and sensitivity. For the treatment of Alzheimer’s disease, complexes 1 and 2 were synthesized as above. Their treatment activity on the Alzheimer’s disease was evaluated, and the specific mechanism was investigated as well. Western blot was used to detect the accumulation of Amyloid protein in neurons. Then, the real time RT-PCR was implemented to assess autophagy related genes expression levels.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

Data Availability

The data used to support the findings of this study are included within the article.

Change history

References

  1. S. Y. Park, B. H. Byun, B. I. Kim, S. M. Lim, I. O. Ko, K. C. Lee, K. M. Kim, Y. K. Kim, J. Y. Lee, S. H. Bu, J. H. Kim, D. Y. Chi, and J. H. Ha (2020). Medicine 99, e19620.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. P. Walsh, C. H. Sudre, C. M. Fiford, N. S. Ryan, T. Lashley, C. Frost, and J. Barnes (2020). Neurobiol. Aging 91, 5.

    Article  CAS  PubMed  Google Scholar 

  3. K. S. Abd-Elrahman, A. Hamilton, A. Albaker, and S. S. G. Ferguson (2020). ACS Pharmacol. Transl. Sci. 3, 334.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. L. Fan, Z. Liu, Y. Zhang, F. Wang, D. Zhao, J. Yang, and X. Zhang (2019). New J. Chem. 43, 13349.

    Article  CAS  Google Scholar 

  5. L. Fan, Y. Zhang, J. Liang, X. Wang, H. Lv, J. Wang, L. Zhao, and X. Zhang (2018). CrystEngComm 20, 4752.

    Article  CAS  Google Scholar 

  6. L. Fan, F. Wang, D. Zhao, X. Sun, H. Chen, H. Wang, and X. Zhang (2020). Spectrochim. Acta A 239, 118467.

    Article  CAS  Google Scholar 

  7. L. Fan, F. Wang, D. Zhao, Y. Peng, Y. Deng, Y. Luo, and X. Zhang (2020). Appl. Organomet. Chem. 239, e5960.

    Article  Google Scholar 

  8. S. L. Cai, L. Lu, W. P. Wu, J. Wang, Y. C. Sun, A. Q. Ma, A. Singh, and A. Kumar (2019). Inorg. Chim. Acta 484, 291.

    Article  CAS  Google Scholar 

  9. J. X. Li, Z. X. Du, Q. Y. Pan, L. L. Zhang, and D. L. Liu (2020). Inorg. Chim. Acta 509, 119677.

    Article  CAS  Google Scholar 

  10. J. X. Li, Z. X. Du, L. L. Zhang, D. L. Liu, and Q. Y. Pan (2020). Inorg. Chim. Acta 512, 119890.

    Article  CAS  Google Scholar 

  11. J. X. Li and Z. X. Du (2020). J. Clust. Sci. 31, 507.

    Article  CAS  Google Scholar 

  12. M. Arshad, H. L. Du, M. S. Javed, A. Maqsood, I. Ashraf, S. Hussain, W. L. Ma, and H. P. Ran (2020). Ceram. Int. 46, 2238.

    Article  CAS  Google Scholar 

  13. Z. Chen and H. Ahn (2020). Int. J. Autom. Comput. 17, 621.

    Article  Google Scholar 

  14. J. Zhao, J. Zhang, D. Zhang, Z. Hu, and Y. Sun (2021). Sci. Total Environ. 752, 141932.

    Article  CAS  PubMed  Google Scholar 

  15. D. M. Chen and X. J. Zhang (2019). CrystEngComm 21, 4696.

    Article  CAS  Google Scholar 

  16. G. Cui, C. H. He, C. H. Jiao, J. C. Geng, and V. A. Blatov (2012). CrystEngComm 14, 4210.

    Article  CAS  Google Scholar 

  17. G. Cui, J. R. Li, J. L. Tian, X. H. Bu, and S. R. Batten (2005). Cryst. Growth Des. 5, 1775.

    Article  CAS  Google Scholar 

  18. D. M. Chen and X. J. Zhang (2019). J. Solid State Chem. 278, 120906.

    Article  CAS  Google Scholar 

  19. Q. Zhu, T. Sheng, C. Tan, S. Hu, R. Fu, and X. Wu (2011). Inorg. Chem. 50, 7618.

    Article  CAS  PubMed  Google Scholar 

  20. K. Sakai, S. Takahashi, A. Kobayashi, T. Akutagawa, T. Nakamura, M. Dosen, M. Kato, and U. Nagashima (2010). Dalton Trans. 39, 1989.

    Article  CAS  PubMed  Google Scholar 

  21. X. X. Jia, R. X. Yao, F. Q. Zhang, and X. M. Zhang (2017). Inorg. Chem. 56, 2690.

    Article  CAS  PubMed  Google Scholar 

  22. M. Y. Sun, D. M. Chen, and H. Zhang (2016). Inorg. Chem. Commun. 73, 103.

    Article  CAS  Google Scholar 

  23. S. Mukherjee, A. V. Desai, B. Manna, A. I. Inamdar, and S. K. Ghosh (2015). Cryst. Growth Des. 15, 4627.

    Article  CAS  Google Scholar 

  24. B. Joarder, A. V. Desai, P. Samanta, S. Mukherjee, and S. K. Ghosh (2015). Chem.: A Eur. J. 21, 965.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Huiqiao Medicai Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China

    Deqiang Zhao, Xiaopu Lin, Meng Lv, Yifan Duan & Mengnan Zhang

  2. Department of Radiotherapy, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China

    Jianhui Chen

Authors
  1. Deqiang Zhao
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Xiaopu Lin
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Meng Lv
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Yifan Duan
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Mengnan Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Jianhui Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jianhui Chen.

Ethics declarations

Conflicts of interest

The author(s) declare(s) that there is no conflict of interest regarding the publication of this paper.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This article has been retracted. Please see the retraction notice for more detail: https://doi.org/10.1007/s10876-024-02558-4"

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zhao, D., Lin, X., Lv, M. et al. RETRACTED ARTICLE: Two Mixed Ligand Coordination Polymers: Selective Detection of TNP and Protective Effect on Alzheimer’s Disease by Stimulating Cell Autophagy. J Clust Sci 33, 113–121 (2022). https://doi.org/10.1007/s10876-020-01935-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10876-020-01935-z

Keywords

Search

Navigation