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Synthesis, Structure, and Spectroscopic Properties of Isotianil as a Bactericide

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Abstract

Isotianil [N-(2-cyanophenyl)-3,4-dichloro-1,2-thiazole-5-carboxamide] has been synthesized in a good yield with high purity by reaction of the key intermediate product, N-(2-carbamoylphenyl)-3,4-dichloro-1,2-thiazole-5-carboxamide, with thionyl chloride in N,N-dimethylformamide at 60°C. The structure of isotianil was studied by X-ray analysis. It crystallized in triclinic space group P1 with a = 11.459(3), b = 12.632(3), c = 22.528(5) Å, α = 78.897(3), β = 81.730(3), γ = 71.493(3)°, Z = 10.

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Authors and Affiliations

  1. Institute of Molecular Engineering and Applied Chemistry, Anhui University of Technology, 243002, Anhui, China

    J. Zhang, J. Ji, B. Wang, A.-Q. Jia & Q.-F. Zhang

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  1. J. Zhang
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  2. J. Ji
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  3. B. Wang
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  4. A.-Q. Jia
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  5. Q.-F. Zhang
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Correspondence to Q.-F. Zhang.

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Zhang, J., Ji, J., Wang, B. et al. Synthesis, Structure, and Spectroscopic Properties of Isotianil as a Bactericide. Russ J Org Chem 56, 1801–1805 (2020). https://doi.org/10.1134/S107042802010022X

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