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Biomineralized and chemically synthesized magnetic nanoparticles: A contrast

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An Erratum to this article was published on 15 May 2021

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Abstract

Magnetic nanoparticles (MNPs) have widely been synthesized through chemical processes for biomedical applications over the past few decades. Recently, a new class of MNPs, known as bacterial magnetosomes, has been isolated from magnetotactic bacteria, a natural source. These magnetosomes are magnetite or greigite nanocrystals which are biomineralized in the bacterial cell and provide magnet-like properties to it. Contrary to MNPs, bacterial magnetosomes are biocompatible, lower in toxicity, and can be easily cleared from the body due to the presence of a phospholipid bilayer around them. They also do not demonstrate aggregation, which makes them highly advantageous. In this review, we have provided an in-depth comparative account of bacterial magnetosomes and chemically synthesized MNPs in terms of their synthesis, properties, and biomedical applications. In addition, we have also provided a contrast on how magnetosomes might have the potential to successfully substitute synthetic MNPs in therapeutic and imaging applications.

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Acknowledgements

This work was financially supported by a grant from the Department of Science and Technology (DST-SERB project; Grant No. ECR/2017/000049), Government of India, for which the authors are thankful. The authors acknowledge Institute of Nano Science and Technology for the facilities and assistance provided to carry out this project.

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  1. Tanya Nanda

    Present address: Present address: School of Biological and Health Systems Engineering, Ira A. Fulton Schools of Engineering, Arizona State University, Tempe, AZ, 85281, USA

  2. Ankita Rathore

    Present address: Present address: Academy of Scientific and Innovative Research (AcSir), CSIR-National Institute of Science Communication and Information Resources (NISCAIR), New Delhi, 110067, India

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  1. Institute of Nano Science and Technology, Habitat Centre, Sector 64, Mohali, 160062, India

    Tanya Nanda, Ankita Rathore & Deepika Sharma

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Nanda, T., Rathore, A. & Sharma, D. Biomineralized and chemically synthesized magnetic nanoparticles: A contrast. Front. Mater. Sci. 14, 387–401 (2020). https://doi.org/10.1007/s11706-020-0531-7

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