Fluoride bioactive glass paste improves bond durability and remineralizes tooth structure prior to adhesive restoration

doi:10.1016/j.dental.2020.10.008

Dental Materials

Volume 37, Issue 1, January 2021, Pages 71-80

https://doi.org/10.1016/j.dental.2020.10.008 Get rights and content

Highlights

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Fluoride bioactive glass (FBG) paste can be used as a temporary filling material capable of remineralizing enamel and dentin.
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The FBG can be applied on demineralized enamel and dentin after cavity preparation followed by bonding procedures.
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The current technique conserves the demineralized enamel and dentin that were routinely removed during cavity preparation.
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FBG application on dentin helps in decreasing the effect of pulpal pressure on the dentin-resin interface.
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FBG application does not affect the shear bond strength of a universal bond to either enamel or dentin.

Abstract

Objective

The current study aimed at examining a fluoride containing bioactive glass (BiominF®) paste as a temporary filling material capable of remineralizing the demineralized enamel or dentin, and its ability to decrease a simulated dentinal fluids pressure on the resin/dentin interface, without affecting the shear bond strength of a universal bonding agent to enamel and dentin.

Methods

60 premolars were utilized for the acid resistance, trans-microradiography (TMR) and shear bond strength (SBS) experiments. Enamel and dentin discs were demineralized for 4 days to create a subsurface demineralized zone followed by applying BiominF® paste, 1.23% acidulated phosphate fluoride, or a temporary filling material for 24 h.

30 extracted human non-carious third molars were utilized for the pulpal pressure experiment in which direct communication to the pulp chamber was created by cutting at a level approximately 1 mm below the cemento-enamel junction while the coronal enamel was ground to expose mid coronal dentin. The dentin surface was exposed to a simulated pulpal pressure. The dentin surfaces had BiominF® paste, an oxalate desensitizing agent, or temporary filling material followed by application of a universal adhesive system.

Results

One way ANOVA showed that BiominF® paste remineralized effectively the demineralized enamel or dentin, did not affect the bond strength of the enamel and dentin surfaces to the tested adhesive system p < 0.05, and improved the acid resistance of the demineralized enamel and dentin against a secondary erosive challenge. Moreover, BiominF® paste decreased the nanoleakage expression in the dentin/adhesive interface exposed to a simulated pulpal pressure.

Significance

BiominF® paste may serve as a temporary filling material that may improve the longevity of adhesive restorations and help to conserve tooth structures by preserving the demineralized enamel and dentin form cutting during cavity preparation.

Graphical abstract

Introduction

Modern adhesive dentistry provided patients with many optimal solutions for treating their carious teeth however, the durability of adhesive restorations and increasing their longevity inside patients’ oral cavities are among the main aims of development in dental field [1].

One of the limitations of adhesive resins is its questionable ability to be bonded to demineralized enamel and dentin [2]. Although, many adhesive systems nowadays involve the phosphoric acid monomer 10-MDP to provide protection to the tooth cavities’ enamel and dentin cavosurface margins [[3], [4], [5]], previous research indicated that 10-MDP monomer has limited protective effect on phosphoric acid etched dentin [6]. Moreover, the prevalence of Molar Incisor Hypomineralization (MIH) recently increased reaching 4–20% incidence [7]. This increases the demands of using effective remineralization strategies capable of restoring the teeth calcium and phosphate levels to their original levels within a short duration of time prior to bonding these hypomineralized enamel surfaces to adhesive restorative materials [8].

Other challenges faced by adhesive restorations is its limited ability to remineralize the enamel and dentin walls due to the resinous matrix of these materials that limit the transfer of any inorganic ions from the restorative material to the bonded enamel [9] or dentin walls. Moreover, the nanoleakage expression at the dentin resin interface is an indication for decreased durability of resin-dentin durability and possible short term degradation of the hybrid layer [10] especially after etching the dentin surface exposed to pulpal pressure [11]. The use of bioactive glasses for the remineralization of enamel and dentin surfaces through forming a calcium phosphate rich layer showed promising results during the past ten years [[11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21]].

This study tested the potential of using a fluoride bioactive glass (FBG) as a temporary filling material prior to bonding procedures. The null hypotheses in the current study are that FBG paste will not (a) Remineralize the demineralized enamel or dentin. (b) Improve the acid resistant of enamel and dentin resin interface at the cavosurface margin. (c) Decrease the nanoleakage expression due to pulpal pressure at the resin-dentin interface.

Section snippets

Materials and methods

The experimental procedures and materials tested are summarized in Fig. 1, and Table 1. 120 teeth were utilized in the current experiment.

Trans-microradiography (TMR) experiment

Statistical analysis for ΔZ (mineral loss), lesion depth, in addition to representative TMR images are presented in (Fig. 2, Table 2, Table 3). (Biomin) group showed significant low ΔZ values when compared to the Fluoride 24 h and the Temporary groups (p ≥ 0.05). There was no statistical significance in ΔZ values among the fluoride 24 h and the temporary groups for enamel and dentin specimens p ≥ 0.05. All of the examined groups in the current study did not show any significant difference

Discussion

The null hypotheses in the current study were totally rejected; FBG paste improved the acid resistance of the demineralized enamel and dentin cavosurface margin. Moreover, FBG paste application did not affect the shear bond strength of the Clearfil universal bond to enamel or dentin. Additionally, FBG paste decreased the deteriorating effect of the pulpal pressure on the bond-dentin interface.

Previous research showed that 10-MDP monomer can form insoluble salts with the inorganic components of

Conclusions

Within the limitations of the current in-vitro study, it may be suggested that the application of the FBG as a temporary filling material may provide the following advantages: (a) Remineralize the demineralized enamel and dentin surfaces allowing for the possibility of preparing more conservative teeth cavities. (b) Does not decrease the shear bond strength of enamel and dentin to a one bottle universal bonding system applied in etch and rinse mode. (c) Provide sealing for the resin-dentin

Funding

This project was funded by the research and development office (RDO) at the ministry of education, Kingdom of Saudi Arabia, Grant no (HIQI-11-2019). The authors also, acknowledge with thanks Adminestration of Support For Research and Development Initiatives at King Abdulaziz University for technical support.

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To prepare a bioactive dentin adhesive and investigate its effect on promoting bonding durability of dentin.
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Citation Excerpt :
Biomin F is a bioactive glass augmented with fluoride to boost its bioactivity [5]. Biomin F showed its ability to release high doses of calcium and phosphate that will be deposited onto tooth structure forming an (Interaction Layer) [5]. This layer can release its rich calcium and phosphorus ions into the internal demineralized tooth structures causing its remineralization [5].
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Half number of the enamel and dentin specimens from each group were challenged by a buffered demineralizing solution, which is composed of 1% citric acid for 18 min, while the rest of the specimens served as controls. The currently selected erosion challenge model was selected after conducting multiple pilot studies and following the procedures recommended in previously published articles [2,12,13,17,18]. The specimens were continuously stirred by a magnetic stirrer to ensure demineralization of all their treatment windows.
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View full text

Fluoride bioactive glass paste improves bond durability and remineralizes tooth structure prior to adhesive restoration

Highlights

Abstract

Objective

Methods

Results

Significance

Graphical abstract

Introduction

Section snippets

Materials and methods

Trans-microradiography (TMR) experiment

Discussion

Conclusions

Funding

Dent Mater

J Dent

Dent Mater

Am J Orthod Dentofacial Orthop

Dent Mater

J Dent

J Dent

Dent Mater

Dent Mater

J Dent

Arch Oral Biol

J Dent

Acta Biomater

Biomaterials

Microshear bond strength of resin composite to teeth affected by molar hypomineralization using 2 adhesive systems

Pediatr Dent

Phosphoric acid-etching promotes bond strength and formation of acid-base resistant zone on enamel

Oper Dent

Morphological evaluation of the adhesive/enamel interfaces of two-step self-etching adhesives and multimode one-bottle self-etching adhesives

J Adhes Dent

Effects of different tooth conditioners on the bonding of universal self-etching adhesive to dentin

J Adhes Dent

MIH supplementation strategies: prospective clinical and laboratory trial

J Dent Res

Effect of Er:YAG laser on dentin bonding durability under simulated pulpal pressure

J Adhes Dent