Detection of human auditory evoked brain signals with a resilient nonlinear optically pumped magnetometer

Highlights

• We have built and tested an Optically Pumped Magnetometer based on non-linear magnetooptical rotation.

• We present a new approach to OPM- based MEG using a modular NOPM sensor.

• Our sensor is resilient to non-zero and non-uniform magnetic field environments and crosstalk free.

• We demonstrate the operation of the NOPM sensor by measuring auditory response and calculating time-frequency representation of power.

Abstract

Optically Pumped Magnetometers (OPMs) have been hailed as the future of human magnetoencephalography, as they enable a level of flexibility and adaptability that cannot be obtained with systems based on superconductors. While OPM sensors are already commercially available, there is plenty of room for further improvements and customization. In this work, we detected auditory evoked brain fields using an OPM based on the nonlinear magneto-optical rotation (NMOR) technique. Our sensor head, containing only optical and non-magnetizable elements, is connected to an external module including all the electronic components, placed outside the magnetically shielded room. The use of the NMOR allowed us to detect the brain signals in non-zero magnetic field environments. In particular, we were able to detect auditory evoked fields in a background field of 70 nT. We benchmarked our sensor with conventional SQUID sensors, showing comparable performance. We further demonstrated that our sensor can be employed to detect modulations of brain oscillations in the alpha band. Our results are a promising stepping-stone towards the realization of resilient OPM-based magnetoencephalography systems that do not require active compensation.