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Microwave-assisted one-pot quick synthesis of 1-monosubstituted 1,2,3-triazoles from arylboronic acids, sodium azide and 3-butyn-2-ols

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Abstract

Microwave-assisted one-pot quick synthesis to 1-monosubstituted 1,2,3-triazoles was achieved with good to excellent yields using the widely available arylboronic acids, sodium azide and 3-butyn-2-ols within 15 min. This method features high efficient and facile as organic azides, acetylene gas and harsh conditions were avoided.

Graphic abstract

Microwave-assisted one-pot quick synthesis to 1-monosubstituted 1,2,3-triazoles was achieved with good to excellent yields using the widely available arylboronic acids, sodium azide and 3-butyn-2-ols within 15 min.

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Acknowledgements

We are grateful for the financial support provided by the Natural Science Foundation of Yunnan Education Department (No. 2020J0768).

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  1. Kunming Metallurgy College, No. 388 Xuefu Road, Kunming, 650033, People’s Republic of China

    ZHONGLIN DU, FENRUI LI, LI LI & RAN LI

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  1. ZHONGLIN DU
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Correspondence to ZHONGLIN DU.

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DU, Z., LI, F., LI, L. et al. Microwave-assisted one-pot quick synthesis of 1-monosubstituted 1,2,3-triazoles from arylboronic acids, sodium azide and 3-butyn-2-ols. J Chem Sci 132, 154 (2020). https://doi.org/10.1007/s12039-020-01856-4

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