Abstract
Pyridazines hold considerable interest relative to pharmacologically active molecules. The pyridazine compounds are exhibited different types of pharmacological activities. The various pyridazine drugs are shown phosphodiestrase (PDE) inhibitor, positive inotropic, vasodilation, analgesic, antiiflamatory, antimicrobial, antidepressant, antipsychotic, antianxiety, antifeeedant, herbicidal, insecticidal, plant growth regulatory, molluscicidal and other biological and agrochemical activities. Pyridazine derivatives focused consideration because of their effortless fuctionalization at various ring positions, which creates them striking compounds for designing and progress of the new pyridazine drugs in future.
Similar content being viewed by others
REFERENCES
Asif, M., Abida, and Alam, M.T., Chem. Int., 2019, vol. 5, pp. 206–231. https://doi.org/10.5281/zenodo.2525555
Abd El-Wahab, A.H.F., Mohamed, H.M., El-Agrody, A.M., El-Nassag, M.A., and Bedair, A.H., Pharmaceuticals, 2011, vol. 4, pp. 1158–1170. https://doi.org/10.3390/ph4081158
Asif, M., Mini Rev. Med. Chem., 2015, vol. 14, pp. 1093–103. https://doi.org/10.2174/1389557514666141127143133
Faidallah, H.M., Khan, K.A., and Makki, M.S.I., J. Chin. Chem. Soc., 2011, vol. 58, pp. 191–198. https://doi.org/10.1002/jccs.201190076
Károlyházy, L., Krajsovszky, G., Farkas, L., Boros, S., Csámpai, A., and Mátyus, P., ARKIVOC, 2011, vol. II, pp. 18–28. https://doi.org/10.3998/ark.5550190.0012.202
Unsal Tan, O.,Ozadali, K., Yes, O.¸ Ilyurt Kayir, H., and Uzbay Tand Balkan, A., Turk. J. Chem., 2011, vol. 35, pp. 121–130. https://doi.org/10.3906/kim-1004-584
Asif, M., Asian J.Chem. Pharm. Sci., 2016, vol. 1, pp. 29–35. https://doi.org/10.18311/ajcps/2016/7693
Yuefen, Z., Lian, S.L., Peter, S.D., Douglas, E.M., Chinh, V.T., Frank, R., Stephen, E.W., Amit, M.S., Mei, T., April, A., Richard, E.S., Rupal, P., Qing, H., Qiang, Z., Thomas, H., Charles, R.K., Laurie, L., and Maria, V.S., Bioorg. Med. Chem. Lett., 2008, vol. 18, pp. 1419–1424. https://doi.org/10.1002/jhet.890
Salvi, V.K., Bhambi, D., Jat, J.L., and Talesara, G.L., ARKIVOC, 2006, vol. XIV, pp. 133–140. https://doi.org/10.3998/ark.5550190.0007.e15
Demirayak, S., Karaburun, A. C., Kayagil, I., Erol, K., and Sirmagul, B., Arch. Pharmacal. Res., 2004, vol. 27, pp. 13–18. https://doi.org/10.1007/BF02980038
Kurup, A., Garg, R., Carini, D. J., Hansch, C., Chem. Rev., 2001, vol. 101, pp. 2727–2750. https://doi.org/10.1021/cr000025g
Asif, M., J. Chin. Pharm. Sci., 2016, vol. 25, pp. 707–725. https://doi.org/10.5246/jcps.2016.10.08
Asif, M., Singh, A., Lakshmayya, Husain, A., and Siddiqui, A.A., Lett. Drug Design Discov., 2013, vol. 10, pp. 651–660. https://doi.org/10.2174/1570180811310070013
Asif, M. and Imran, M., A.S. Pharm. Sci., 2019, vol. 3, pp. 48–52. https://doi.org/10.31080/ASPS.2019.03.0275
Zhou, G., Ting, P.C., Aslanian, R., Cao, J., Kim, D., Kuang, R., Lee, J.F., Schwerdt, J., Wu, H., Herr, R.J., Zych, A.J., Yang, J., Lam, S., Wainhaus, S., Black, T.A., McNicholas, P.M., Xu, Y., and Walker, S.S., Bioorg. Med. Chem. Lett., 2011, vol. 21, pp. 2890–2893. https://doi.org/10.1016/j.bmcl.2011.03.083
Asif, M. J. Chem., 2018, vol. 8, pp. 280–300. https://doi.org/10.4172/2161-0444.1000522
Asif, M., Singh, A., Khan, S.A., and Husain, A., Braz. J. Pharm. Sci., 2018. https://doi.org/10.1590/s2175-97902018000300040
Asif, M., Abida, and Imran, M., Int. J. Pharm. Sci. Res., 2020, vol. 11, pp. 826–831. https://doi.org/10.13040/IJPSR.0975-8232.11(2).826-31
Costas, T., Besada, P., Piras, A., Acevedo, L., Yañez, M., Orallo, F., Laguna, R., and Teran, C., Bioorg. Med. Chem. Lett., 2010, vol. 20, pp. 6624–6627. https://doi.org/10.1016/j.bmcl.2010.09.031
Asif, M., J. Mod. Med. Chem., 2015, vol. 3, pp. 31–34. https://doi.org/10.12970/2308-8044.2015.03.01.1
Asif, M., M. O. J. Biorg.Org. Chem., 2018, vol. 2, pp. 36–40. https://doi.org/10.15406/mojboc.2018.02.00053
Cherng, S.C., Huang, W.H., Shiau, C.Y., Lee, A.R., and Chou, T.C., Eur. J. Pharmacol., 2006, vol. 1–2, pp. 32–37. https://doi.org/10.1016/j.ejphar.2005.12.022
Abouzid, K., Hakeem, M.A., Khalil, O., and Maklad, Y., Bioorg. Med. Chem., 2008, vol. 16, pp. 382–389. https://doi.org/10.1016/j.bmc.2007.09.031
Asif, M., J. Pharm. Res., 2017, vol. 16, pp. 43–48. https://doi.org/10.23880/oajpr-16000117
Asif, M., Centr.Eur. J. Exp.Biol., 2017, vol. 5, pp. 1–19.
Asif, M., J. Pharm, Res., 2017, vol. 1, p. 000117.
Asif, M., J. Chin. Pharm. Sci., 2017, vol. 26, pp. 1–22.https://doi.org/10.5246/jcps.2016.10.080
Asif, M. and Singh, A., Open Pharm. Sci. J., 2016, vol. 3, pp. 203–214. https://doi.org/10.2174/187484490160301019
Derson, V., Ward, R., and Watson, L., Bioorg. Med. Chem. Lett., 2009, vol. 19, pp. 5791–5795. https://doi.org/10.1016/j.bmcl.2009.07.136
Archan, S. and Toller, W., Curr. Opin. Anaesthesiol., 2008, vol. 21, pp. 78–84. https://doi.org/10.1097/ACO.0b013e3282f357a5
Karlsberg, R.P., DeWood, M.A., DeMaria, A.N., Berk, M.R., and Lasher, K.P., Clin. Cardiol., 1996, vol. 19, pp. 21–30. https://doi.org/10.1002/clc.4960190106
Owings, F.F., Fox, M., Kowalski, C.J., and Baine, N.H., J. Org. Chem., 1991, vol. 56, pp. 1963–1966.
Higuchi, T., Nekolla, S.G., Huisman, M.M., Reder, S., Poethko, T., Yu, M., Wester, H.J., Casebier, D.S., Robinson, S.P., Botnar, R.M., and Schwaiger, M., J. Nucl. Med., 2008, vol. 49, pp. 1715–1722. https://doi.org/10.2967/jnumed.108.053967
Purohit, A., Radeke, H., Azure, M., Hanson, K., Benetti, R., Su, F., Yalamanchili, P., Yu, M., Hayes, M., Guaraldi, M., Kagan, M., Robinson, S., and Casebier, D., J. Med. Chem., 2008, vol. 51, pp. 2954–2970. https://doi.org/10.1021/jm701443n
Asif, M., Mini Rev. Org. Chem., 2013, vol. 10, pp. 113–122. https://doi.org/10.2174/1570193X11310020001
Islam, M., Siddiqui, A.A., and Rajesh, R., Acta Pol. Pharm., 2008, vol. 65, pp. 441–447. pmid: 19051585.
Asif, M., Anita, S., Lakshmayya, Siddiqui, A.A., and Husain, A., Acta Pharm. Sci., 2011, vol. 53, pp. 563–575.
Erden, B., Murat, S., Ukuroglu Burcu, C., Alis Kanergun, Sultan, N. B., Eda, A., and Mustafa, A.R.K., Turk. J. Chem., 2007, vol. 31, pp. 677–687.
Sukuroglu, M., Ergun, B.C., Unlu, S., Sahin, M. F., Kupeli, E., Yesilada, E., and Banoglu, E., Arch. Pharm. Res., 2005, vol. 28, pp. 509–517. https://doi.org/10.1007/BF02977751
Gokce, M., Utku, S., and Kupeli, E., Eur. J. Med. Chem., 2009, vol. 44, pp. 3760–3764. https://doi.org/10.1016/j.ejmech.2009.04.048
Rathish, I.G., Javed, K., Bano, S., Ahmad, S., Alam, M.S., and Pillai, K.K., Eur. J. Med. Chem., 2009, vol. 44, pp. 2673–2678. https://doi.org/10.1016/j.ejmech.2008.12.013
Cao, S., Qian, X., Song, G., Chai, B., and Jiang, Z., J. Agric. Food Chem., 2003, vol. 51, pp. 152–155. https://doi.org/10.1021/jf0208029
Malinka, W., Pharmazie, 2001, vol. 56, pp. 384–389.
Malinka, W., Redzicka, A., and Lozach, O., Farmaco, 2004, vol. 59, pp. 457–462. https://doi.org/10.1016/j.farmac.2004.03.002
Schudt, C., Winder, S., Müller, B., and Ukena, D., Biochem. Pharmacol., 1991, vol. 21, pp. 153–162. https://doi.org/10.1016/0006-2952(91)90694-z
Siddiqui, A.A., Mishra, R., and Shaharyar, M., Eur. J. Med. Chem., 2010, vol. 45, pp. 2283–2290. https://doi.org/10.1016/j.ejmech.2010.02.003
Yamamoto, A., Iwama, T., Takeda, H., and Nagai, H., Jpn. J. Pharmacol., 1995, vol. 68, pp. 47–55. https://doi.org/10.1254/jjp.68.47
Jeremy, R.G., Graziano, V., Hugh, R.C., Kenneth, N.M., and Robin, D.A., J. Mol. Str. (Theochem), 1996, vol. 368, pp. 235–243. https://doi.org/10.1016/S0166-1280(96)90517-5
Chen, H., Li, Z., and Han, Y., J. Agric. Food Chem., 2000, vol. 48, pp. 5312–5315. https://doi.org/10.1021/jf991065s
Abdelrazek, F.M., Michael, F.A., and Mohamed, A.E., Arch. Pharm. (Weinheim), 2006, vol. 339, pp. 305–312. https://doi.org/10.1002/ardp.200500259
Xu, H., Zou, X.M., Zhu, Y.Q., Liu, B., Tao, H. L., Hu, X. H., Song, H. B., Hu, F. Z., Wang, Y., and Yang, H.Z., Pest. Manage. Sci., 2006, vol. 62, pp. 522–530. https://doi.org/10.1002/ps.1195
Coudert, P., Duroux, E., Bastide, P., Couquelet, J., and Tronche, P., J. Pharm. Belg., 1991, vol. 46, pp. 375–380.
Allerton, C.M., Andrews, M. D., Blagg, J., Ellis, D., Evrard, E., Green, M. P., Liu, K.K., McMurray, G., Ralph, M., Sanderson, V., Ward, R., and Watson, L., Bioorg. Med. Chem. Lett., 2009, vol. 1, pp. 5791–5795. https://doi.org/10.1016/j.bmcl.2009.07.136
Huang Q, Kong Y, Liu M, Feng J, Liu Y. J Insect Sci. 2008, vol. 8, pp. 1577–1580. https://doi.org/10.1673/031.008.1901
Griebel, G., Perrault, G., Sanger, D.J. Pharmacol. Biochem. Behav., 1999, vol. 62, pp. 689–694. https://doi.org/10.1016/s0091-3057(98)00209-3
Wang, T.,Dong, Y.,Wang, L.C.,Xiang, B.R.,Chen, Z., Qu, L.B. Arzneimittelforschung, 2008, vol. 58, pp. 569–573. https://doi.org/10.1055/s-0031-1296558
Barbaro, R., Betti, L., Botta, M., Corelli, F., Giannaccini, G., Maccari, L., Manetti, F., Strappaghetti, G., Corsano, S. J. Med. Chem., 2001, vol. 44, pp. 2118–2132. https://doi.org/10.1021/jm010821u
Maemoto, T., Tada, M., Mihara, T., Ueyama, N., Matsuoka, H., Harada, K., Yamaji, T., Shirakawa, K., Yamaji, T., Shirakawa, K., Kuroda, S., Akahane, A., Iwashita, A., Matsuoka, N., Mutoh, S. J. Pharm. Sci., 2004, vol. 96, pp. 42–52. https://doi.org/10.1254/jphs.fp0040359
Yalamanchili, P.,Wexler, E.,Hayes, M., Yu, M., Bozek, J., Kagan, M., Radeke, H.S., Azure, M., Purohit, A., Casebier, D.S., Robinson, S. P. J.Nucl. Cardiol., 2007, vol. 14, pp. 782–788. https://doi.org/10.1016/j.nuclcard.2007.07.009
Gong, Y., Barbay, J.K., Dyatkin, A.B., Miskowski, T.A., Kimball, E.S., Prouty, S.M., Fisher, M.C., Santulli, R.J., Schneider, C.R., Wallace, N.H., Ballentine, S.A., Hageman, W.E., Masucci, J.A., Maryanoff, B.E., Damiano, B.P., Andrade-Gordon, P., Hlasta, D.J., Hornby, P.J., and He, W., J. Med. Chem., 2006, vol. 49, pp. 3402–3411. https://doi.org/10.1021/jm060031q
Youssef, A.S.A., Marzouk, M.I., Madkour, H.M.F., El-Soll, M.A., and El-Hashash, M.A., Can. J. Chem., 2005, vol. 83, pp. 251–259. https://doi.org/10.1139/v05-045
Demirayak, S., Karaburun, A.C., Beis, R., Eur. J. Med. Chem., 2004, vol. 39, pp. 1089–1095. https://doi.org/10.1016/j.ejmech.2004.09.005
Murray, K.J., Drug News Perspect., 1993, vol. 6, pp.150–156.
Yamaguchi, M., Kamei, K., Koga, T., Akima, M., Kuroki, T., and Ohi, N., J. Med. Chem., 1993, vol. 36, pp. 4052–4060. https://doi.org/10.1021/jm00077a008
Li, Y.X., Luo, Y.P., Xi, Z., Niu, C., He, Y.Z., amd Yang, G.F., J. Agric. Food Chem., 2006, vol. 54, pp. 9135–9139. https://doi.org/10.1021/jf061976j
Kumar, D.,Carron, R., La Calle, C.D., Jindal, D.P., and Bansal, R., Acta Pharm., 2008, vol. 58, pp. 393–405. https://doi.org/10.2478/v1007-008-0021-4
Combs, D.W., Rampulla, M.S., Bell, S.C., Klaubert, D.H., Tobia, A.J., Falotico, R., Haertlein, B., Lakas-Weiss, C., and Moore, J.B., J. Med. Chem., 1990, vol. 33, pp. 380–386. https://doi.org/10.1021/jm00163a061
Nomoto, Y., Takai, H., Ohno, T., and Kubo, K., Chem. Pharm. Bull. (Tokyo), 1991, vol. 39, pp. 352–357. https://doi.org/10.1248/cpb.39.352
Ishimori, T.,Gotanda, K.,Sasaki, T., Shinbo, A., Asano, H., Miyazawa, K., and Miyasaka, K., Arzneimittelforschung, 1994, vol. 44, pp. 583–588.
Araki, S.,Uematsu, T.,Nagashima, S., Matsuzaki, T., Gotanda, K., Ochiai, H., Hashimoto, H., and Nakashima, M., Gen. Pharmacol., 1997, vol. 28, pp. 545–53. https://doi.org/10.1016/s0306-3623(96)00302-3
Uhlmann, R., Schwinger, R.H., Lues, I., and Erdmann, E., Basic Res. Cardiol., 1995, vol. 90, pp. 365–371. https://doi.org/10.1007/BF00788497
Bowman, P., Haikala, H., and Paul, R.J., J. Pharmacol. Exp. Ther., 1999, vol. 288, pp. 316–325.
Kubo, S.H., Cardiology, 1997, vol. 88, pp. 21–27. https://doi.org/10.1159/000177481
Iwamoto, H., Eur. J. Pharmacol., 1998, vol. 12, pp. 243–252. https://doi.org/10.1016/s0014-2999(97)01469-6
Wang, T., Dong, Y., Wang, L.C., and Chen, Z., Arzneimittelforschung, 2007, vol. 57, pp. 641–646. https://doi.org/10.1055/s-0031-1296662
Pahernik, S.A., Schmid, J., Sauter, T., Schildberg, F.W., and Koebe, H.G., Xenobiotica, 1995, vol. 25, pp. 811–823.
Bellomo, R., Chapman, M., Finfer, S., Hickling, K., and Myburgh, J., Lancet, 2000, vol. 356, pp. 2139–2143. https://doi.org/10.1016/s0140-6736(00)03495-4
Ishiki, R., Ishihara, T., Izawa, H., Nagata, K., Hirai, M., and Yokota, M., J. Cardiovasc. Pharmacol., 2000, vol. 35, pp. 897–905. https://doi.org/10.1097/00005344-200006000-00011
Remme, W.J., Kruijssen, D.A., van Hoogenhuyze, D.C., Krauss, X.H., Bartels, G.L., Storm, C.J., and de Leeuw, P.W., J. Cardiovasc. Pharmacol., 1994, vol. 24, pp. 730–739. https://doi.org/10.1097/00005344-199424050-00007
Kubo, S.H., Gollub, S., Bourge, R., Rahko, P., Cobb, F., Jessup, M., Brozena, S., Brodsky, M., Kirlin, P., and Shanes, J., Circulation, 1992, vol. 85, pp. 942–949. https://doi.org/10.1161/01.cir.85.3.942
Asanoi, H., Kihara, Y., Yokawa, S., Terada, Y., Yoshida, S., Ejiri, M., and Horikoshi, I., Heart Vessels, 1994, vol. 9, pp. 113–120. https://doi.org/10.1007/BF01745236
Lubsen, J., Just, H., Hjalmarsson, A.C., La Framboise, D., Remme, W.J., Heinrich-Nols, Dumont, J.M., and Seed, P., Heart, 1996, vol. 76, pp. 223–231. https://doi.org/10.1136/hrt.76.3.223
Sotelo, E., Coelho, A., and Ravina, E., Chem. Pharm. Bull. (Tokyo), 2003, vol. 51, pp. 427–430. https://doi.org/10.1248/cpb.51.427
Eddy, S., Alberto, C., and Enrique, R., Pharm. Bull., 2003, vol. 51, pp. 427–430.
Przechera, M., Roth, W., Kuhlkamp, V., Risler, T., and Haehl, M., Eur. J. Clin. Pharmacol., 1991, vol. 40, pp. 107–111. https://doi.org/10.1007/BF00315148
Westfall, M.V., Wahler, G.M., and Solaro, R.J., Biochemistry, 1993, vol. 32, pp. 10 464–10 470. https://doi.org/10.1021/bi00090a024
Beier, N., Harting, J., Jonas, R., Klockow, M., Lues, I., and Haeusler, G., J. Cardiovasc. Pharmacol., 1991, vol. 18, pp. 17–27. https://doi.org/10.1097/00005344-199107000-00004
Amin, E.N.,Abdel-Alim, A.A., Abdel-Moty, S.G., El-Shorbagi, A.N., and Abdel-Rahman, M.S.H., Arch. Pharm. Res., 2010, vol. 33, pp. 25–46. https://doi.org/10.1007/s12272-010-2222-x
Ioannou, N. and Wyncoll, D.L., Br. J. Cardiol. (Acute Interv. Cardiol.), 2004, vol. 11, pp. AIC 24–AIC 30.
Levijoki, J., Pollesello, P., and Kaheiner, P., Eur. J. Pharmacol., 2001, vol. 419, pp. 243–248. https://doi.org/10.1016/s0014-2999(01)00997-9
DeLuca, L., Proietti, P., Palombaro, G.L., Battagliese, A., Celotto, A., Ducci, C.B., and Fedele, F., Ital. Heart J., 2004, vol. 5, pp. 63S–67S.
Kersten, J.R., Montgomery, M.W., and Pagel, P.S., Anesth. Analg., 2000, vol. 90, pp. 5–11. https://doi.org/10.1097/00000539-200001000-00003
Luotalahti, M., Lammintausta, O., and Ukkonen, H., Circulation, 1998, vol. 98, pp. 105–106.
Abou-Zeid, K.A.M., Youssef, K.M., Shaaban, M.A., El-Telbany, F.A., and Al-Zanfaly, S.H., Egypt. J. Pharm. Sci., 1998, vol. 38, pp. 319–331.
Nomoto, Y., Takai, H., Ohno, T., Nagashima, K., Yao, K., Yamada, K., Kubo, K., Ichimura, M., Mihara, A., and Kanase, H., J. Med. Chem., 1996, vol. 39, pp. 297–303. https://doi.org/10.1021/jm950197j
Bansal, R., Kumar, D., Carron, R., and de la Calle, C., Eur. J. Med. Chem., 2009, vol. 44, pp. 4441–4447. https://doi.org/10.1016/j.ejmech.2009.06.006
Wang. T., Xiang, B., Wang, Y., Chen, C., Dong, Y., Fang, H., and Wang, M., ColloidsSurf. B: Biointerfaces, 2008, vol. 65, pp. 113–119. https://doi.org/10.1016/j.colsurfb.2008.03.008
Seki, T., Nakao, T., Masuda, T., Hasumi, K., Gotanda, K., Ishimori, T., Honma, S., Minami, N., Shibata, K., and Yasuda, K., Chem. Pharm. Bull. (Tokyo), 1996, vol. 44, pp. 2061–2069. https://doi.org/10.1248/cpb.44.2061
Hasenfuss, G., Pieske, B., Castell, M., Kretschmann, B., Maier, L.S., and Just, H., Circulation, 1998, vol. 98, pp. 2141–2147. https://doi.org/10.1161/01.cir.98.20.2141
Hasenfuss, G., Pieske, B., Kretschmann, B., Holubarsch, C., Alpert, N.R., and Just, H., J. Cardiovasc. Pharmacol., 1995, vol. 26, pp. S45–S51.
Pagel, P.S., Harkin, C.P., and Hettrick, D.A., Anesthesiology, 1994, vol. 81, pp. 974–987.
Schneider, P., Güttner, J., Eckenfels, A., Heinzel, G., von Nicolai, H., Trieb, G., and Lehmann, H., Exp. Toxicol. Pathol., 1997, vol. 49, pp. 217–224. https://doi.org/10.1016/s0940-2993(97)80013-9
Hagemeijer, F., J. Cardiovasc. Pharmacol., 1994, vol. 23, pp. 741–746. https://doi.org/10.1097/00005344-199405000-00008
Jonas, R., Klockow, M., Lues, I., Priicher, H., Schliep, H.J., and Wurziger, H., Eur. J. Med. Chem., 1993, vol. 28, pp. 129–140. https://doi.org/10.1016/0223-5234(93)90005-Y
Chen, H.Z., Cui, X.L., Zhao, H.C., Zhao, L.Y., Lu, J. Y., and Wu, B.W., Acta Physiol. Sin., 2004, vol. 56, pp. 301–305. pmid: 15224141.
Zeng, G.Q., Wang, X.S., Sun, D.X., Lin, A.Y., Ji, Y., Chu, J.X., and Rui, Y.C., Yao Xue Xue Bao, 1993, vol. 28, pp. 256–259.
Nadler, G., Delimoge, I., Lahouratate, P., Leger, I., Morvan, M., Zimmermann, R.G., Eur. J. Med. Chem., 1996, vol. 31, pp. 805–808. https://doi.org/10.1016/0223-5234(96)83974-2
Corsanol, S., Scapicchil, R., Strappaghettil, G., Marucci, G., and Paparelliz, F., Eur. J. Med. Chem., 1995, vol. 30, pp. 7l–75. https://doi.org/10.1016/0223-5234(96)88217-1
Strappaghetti, G., Corsano, S., Barbaro, R., Lucacchini, A., Giannaccini, G., Betti, L. Eur. J. Med. Chem., 1998, vol. 33, pp. 501–508. https://doi.org/10.1016/S0223-5234(98)80050-0
Barrett, J.A., Woltmann, R.F., Swillo, R.S., Kasiewski, C., Faith, W.C., Campbell, H.F., and Perrone, M.H., J. Cardiovasc. Pharmacol., 1990, vol. 16, pp. 537–545. https://doi.org/10.1097/00005344-199010000-00004
Azzolina, O., Dal Piaz, V., Collina, S., Giovannoni, M.P., and Tadini, C., Chirality, 1997, vol. 9, pp. 681–685. https://doi.org/10.1002/(SICI)1520-636X(1997)9:7<681::AID-CHIR8>3.0.CO;2-A
Tsoungas, P.G. and Searcey, M., Tetrahedron Lett., 2001, vol. 42, pp. 6589–6592. https://doi.org/10.1016/S0040-4039(01)01302-8
Sivakumar, R., Gnanasam, S.K., Ramachandran, S., and Leonard, J.T., Eur. J. Med. Chem., 2002, vol. 37, pp. 793–801. https://doi.org/10.1016/s0223-5234(02)01405-8
Dogruer, D.S., Sahin, M.F., Kupeli, E., and Yesilada, E., Arch. Pharm., 2004, vol. 337, pp. 303–310. https://doi.org/10.1002/ardp.200200719
Rubat, C., Coudert, P., Albuisson, E., Bastide, J., Couquelet, J., and Tronche, P., J. Pharm. Sci., 1992, vol. 81, pp. 1084–1087. https://doi.org/10.1002/jps.2600811108
Dogruer, D. S., Sahin, M. F., Unlu, S., and Shigeru, I., Arch. Pharm. (Weinheim), 2000, vol. 333, pp. 79–86. https://doi.org/10.1002/(sici)1521-4184(20004)333:4<79::aid-ardp79>3.0.co;2-s
Piaz, V.D., Giovannoni, M.P., Ciciani, G., Barlocco, D., Giardina, G., Petrone, G., and Clarke, G.D., Eur. J. Med. Chem., 1996, vol. 31, pp. 65–70. https://doi.org/10.1016/S0223-5234(96)80008-0
Pieretti, S., Dal Piaz, V., Matucci, R., Giovannoni, M.P., and Galli, A., Life Sci., 1999, vol. 65, pp. 1381–1394. https://doi.org/10.1016/s0024-3205(99)00377-x
Chintakunta, V.K., Akella, V., Vedula, M.S., Mamnoor, P.K., Mishra, P., Casturi, S.R., Vangoori, A., and Rajagopalan, R., Eur. J. Med. Chem., 2002, vol. 37, pp. 339–347. https://doi.org/10.1016/s0223-5234(02)01336-3
Moreau, S., Coudert, P., Rubat, C., Gardette, D., Vallee-Goyet, D., Couquelet, J., Bastide, P., and Tronche, P., J. Med. Chem., 1994, vol. 37, pp. 2153–2160. https://doi.org/10.1021/jm00040a006
Vigil-De Gracia, P., Lasso, M., Ruiz, E., Vega-Malek, J.C., Mena, F.T., and Lopez, J.C., Eur. J. Obstet. Gynecol. Rep. Biol., 2006, vol. 128, pp. 157–162. https://doi.org/10.1016/j.ejogrb.2006.02.015
Montgomery, S.A., Baldwin, D.S., Priest, R.G., Steinert, J., Patel, A., Herrington, R.N., and Livingston, H.M., Pharmacopsychiatry, 1991, vol. 24, pp. 168–174. https://doi.org/10.1055/s-2007-1014463
Heinisch, G. and Frank, H., in Progress in Medicinal Chemistry, Ellis, G.P. and Luscombe, D.K., Eds., Amesterdam, The Netherlands: Elsevier, 1992, vol. 29, pp. 141–1483.
Haack, T., Fattori, R., Napoletano, M., Pellacini, F., Fronza, G., Raffaini, G., and Ganazzoli, F. Bioorg. Med. Chem., 2005, vol. 13, pp. 4425–4433. https://doi.org/10.1016/j.bmc.2005.04.057
Abdel-Khalik, M.M., Agamy, M.S., and Elnagdi, M.H., Synthesis, 2001, vol. 12, pp. 1861–1865. https://doi.org/10.1055/s-2001-17522
Epsztajn, J., Malinowski, Z., Brzezinki, J.Z., and Karazatka, M., Synthesis (Stuttgart), 2000, vol. 14, pp. 2085–2090. https://doi.org/10.1055/s-0030-1260039
Horn, H., Morgenstern, E., and Univerferth, K., Pharmazie, 1990, vol. 45, pp. 724–727. pmid: 2089381.
Melikian, A., Schiewer, G., Chambon, J.P., and Wermuth, C.G., J. Med. Chem., 1992, vol. 35, pp. 4092–4197. https://doi.org/10.1021/jm00100a015
Eguchi, Y., Sasaki, F., Takashima, Y., Nakajima, M., and Ishikawa, M., Chem. Pharm. Bull., 1991, vol. 39, pp. 795–797. https://doi.org/10.1248/cpb.39.795
Karolak-Wojciechowska, J., Lange, J., Kwiatkowski, W., Gniewosz, M., and Plenkiewicz, J., Bioorg. Med. Chem., 1994, vol. 2, pp. 773–779. https://doi.org/10.1016/s0968-0896(00)82176-8
Araujo, F., Tan, S., Ruano, D., Schoemaker, H., Benavides, J., and Vitorica, J., J Biol. Chem., 1996, vol. 271, pp. 7902–7911. https://doi.org/10.1074/jbc.271.44.27902
Atack, J.R., Smith, A.J., Emms, F., and McKernan, R.M., Neuropsychopharmacology, 1999, vol. 20, pp. 255–262. https://doi.org/10.1016/S0893-133X(98)00052-9
Rowlett, J.K., Spealman, R.D., Lelas, S., Cook, J.M., and Yin, W., Psychopharmacology (Berlin), 2003, vol. 165, pp. 209–215. https://doi.org/10.1007/s00213-002-1275-z
Tonkiss, J., Shultz, P.L., Bonnie, K.E., Hudson, J.L., Duran, P., and Galler, J.R., Nut. Neurosci., 2003, vol. 6, pp. 379–387. https://doi.org/10.1080/10284150310001624200
Mirza, N.R., Rodgers, R.J., and Mathiasen, L.S., J. Pharmacol. Exp. Ther., 2006, vol. 316, pp. 1291–1299. https://doi.org/10.1124/jpet.105.094003
Behrens, C.J., Van Den Boom, L.P., and Heinemann, U., Eur. J. Neurosci., 2007, vol. 25, pp. 2170–2181. https://doi.org/10.1111/j.1460-9568.2007.05462.x
Ueno, S., Bracamontes, J., Zorumski, C., Weiss, D.S., and Steinbach, J.H., J. Neurosci.: J. Soc. Neurosci., 1997, vol. 17, pp. 625–634. pmid: PMC6573228.
Yeung, J.Y., Canning, K.J., Zhu, G., Pennefather, P., MacDonald, J.F., and Orser, B.A., Mol. Pharmacol., 2003, vol. 63, pp. 2–8. https://doi.org/10.1124/mol.63.1.2
Absalom, N., Eghorn, L.F., Villumsen, I.S., Karim, N., Bay, T., Olsen, J.V., Knudsen, G.M., Bräuner-Osborne, H., Frølund, B., Clausen, R.P., Chebib, M., and Wellendorph, P., Proc. Natl. Acad. Sci. U. S. A., 2012, vol. 109, pp. 13 404–13 409. https://doi.org/10.1073/pnas.1204376109
McCabe, C., Shaw, D., Atack, J.R., Street, L.J., Wafford, K.A., Dawson, G.R., Reynolds, D.S., and Leslie, J.C., Neuropharmacology, 2004, vol. 46, pp. 171–178. https://doi.org/10.1016/j.neuropharm.2003.09.004
Fradley, R.L., Guscott, M.R., Bull, S., Hallett, D.J., Goodacre, S.C., Wafford, K.A., Garrett, E.M., Newman, R.J., O’Meara, G.F., Whiting, P.J., Rosahl, T.W., Dawson, G.R., Reynolds, D.S., and Atack, J.R., J. Psychopharmacol., 2007, vol. 21, pp. 384–391. https://doi.org/10.1177/0269881106067255
Atack, J.R., Expert Opin. Investig. Drugs, 2005, vol. 14, pp. 601–618. https://doi.org/10.1517/13543784.14.5.601
Morris, H.V., Dawson, G.R., Reynolds, D.S., Atack, J.R., and Stephens, D.N., Eur. J. Neurosci., 2006, vol. 23, pp. 2495–2504. https://doi.org/10.1111/j.1460-9568.2006.04775.x
Mathiasen, L.S., Rodgers, R.J., and Mirza, N.R., Behav. Pharmacol., 2007, vol. 18, pp. 191–203. https://doi.org/10.1097/FBP.0b013e32814fcdd4
Ujfalussy, B., Kiss, T., Orbán, G., Hoffmann, W.E., Erdi, P., and Hajós, M., Neuropharmacology, 2007, vol. 52, pp. 733–743. https://doi.org/10.1016/j.neuropharm.2006.09.022
Mirza, N.R., Rodgers, R.J., and Mathiasen, L.S., J. Pharmacol. Exp. Ther., 2006, vol. 316, pp. 1291–1299. https://doi.org/10.1124/jpet.105.094003
Mathiasen, L. and Mirza, N.R., Psychopharmacology (Berlin), 2005, vol. 182, pp. 475–484. https://doi.org/10.1007/s00213-005-0119-z
Nakao, T., Obata, M., Kawakami, M., Morita, K., Tanaka, H., Morimoto, Y., Takehara, S., Yakushiji, T., and Tahara, T., Chem. Pharm. Bull. (Tokyo). 1991, vol. 39, pp. 2556–1563. https://doi.org/10.1248/cpb.39.2556
Nakao, T., Obata, M., Yamaguchi, Y., Marubayashi, N., Ikeda, K., and Morimoto, Y., Chem. Pharm. Bull. (Tokyo), 1992, vol. 40, pp. 117–121. https://doi.org/10.1248/cpb.40.117
Yakushiji, T., Shirasaki, T., Munakata, M., Hirata, A., and Akaike, N., Br. J. Pharmacol., 1993, vol. 109, pp. 819–825. https://doi.org/10.1111/j.1476-5381.1993.tb13648.x
Yasumatsu, H., Morimoto, Y., Yamamoto, Y., Takehara, S., Fukuda, T., Nakao, T., and Setoguchi, M., Br. J. Pharmacol., 1994, vol. 111, pp. 1170–1178. https://doi.org/10.1111/j.1476-5381.1994.tb14868.x
Griebel, G., Perrault, G., and Sanger, D.J., Pharmacol. Biochem. Behav., 1999, vol. 62, pp. 689–694. https://doi.org/10.1016/s0091-3057(98)00209-3
Griebel, G., Perrault, G., Tan, S., Schoemaker, H., and Sanger, D.J., Behav. Pharmacol., 1999, vol. 10, pp. 483–495. https://doi.org/10.1097/00008877-199909000-00007
Aleeva, G.N., Molodavkin, G.M., and Voronina, T.A., Bull. Exp. Biol. Med., 2009, vol. 148, pp. 54–56. https://doi.org/10.1007/s10517-009-0638-4
Macor, J.E., Annual Reports in Medicinal Chemistry, Boston: Academic, 2009, vol. 44.
Shinaev, N.N. and Akzhigitov, R.G., Zh. Nevropatol. Psikhiatr. im. S.S. Korsakova, 2005, vol. 105, pp. 55–56. https://doi.org/10.1002/14651858
Valdman, A.V., Avdulov, N.A., Rozganets, V.V., and Rusacov, D.Y., Acta Physiol. Pharmacol. Bulg., 1983, vol. 9, pp. 3–10.
Kan, J.P., Steinberg, R., Leclercq, J., Worms, P., and Biziere, K., J. Neurochem., 1988, vol. 50, pp. 1137–1144. https://doi.org/10.1111/j.1471-4159.1988.tb10584.x
Kan, J.P., Steinberg, R., Mouget-Goniot, C., Worms, P., and Bizière, K., J. Pharmacol. Exp. Ther., 1987, vol. 240, pp. 251–258.pmid:3100771
Davies, L.P., Barlin, G.B., Ireland, S.J., and Ngu, M.M., Biochem. Pharmacol., 1992, vol. 44, pp. 1555–1561. https://doi.org/10.1016/0006-2952(92)90472-u
Behren,s, C.J., Van Den Boom, L.P., and Heinemann, U., Eur. J. Neurosci., 2007, vol. 25, pp. 2170–2781. https://doi.org/10.1111/j.1460-9568.2007.05462.x
Ueno, S., Bracamontes, J., Zorumski, C., Weiss, D.S., and Steinbach, J.H., J. Neurosci., 1997, vol. 17, pp. 625–634.
Yeung, J.Y., Canning, K.J., Zhu, G., Pennefather, P., MacDonald, J.F., and Orser, B.A., Mol. Pharmacol., 2003, vol. 63, pp. 2–8. https://doi.org/10.1124/mol.63.1.2
Absalom, N., Eghorn, L.F., Villumsen, I.S., Karim, N., Bay, T., Olsen, J.V., Knudsen, G.M., Bräuner-Osborne, H., Frølund, B., Clausen, R.P., Chebib, M., and Wellendorph, P., Proc. Natl. Acad. Sci. U. S. A., 2012, vol. 109, pp. 13 404–13 409. https://doi.org/10.1073/pnas.1204376109
Ito, S., Yamaguchi, K., and Komoda, Y., Chem. Pharm. Bull., 1992, vol. 40, pp. 3327–3329. https://doi.org/10.1248/cpb.40.3327
Arakawa, H., Ishida, J., Yamaguchi, M., and Nakamura, M., Chem. Pharm. Bull., 1990, vol. 38, pp. 3491–3499.
Arakawa, H., Ishida, J., Yamaguchi, M., and Nakamura, M., Chem. Pharm. Bull., 1991, vol. 39, pp. 411–419. https://doi.org/10.1248/cpb.39.411
Samoto, K. and Ohkura, Y., Chem. Lett., 1990, vol. 19, pp. 1323–1326.
Napoletano, M., Norcini, G., Pellacini, F., Morazzoni, G., Ferlenga, P., and Pradella, L., Bioorg. Med. Chem. Lett., 2001, vol. 11, pp. 33–37. https://doi.org/10.1016/s0960-894x(00)00587-4
Kikuchi, K., Nagano, T., Hayakawa, H., Hirata, Y., and Hirobe, M., Anal. Chem., 1999, vol. 22, pp. 5131–5136.
Laudadio, C. and Sima, A.A., J. Diabet. Complic., 1998, vol. 12, pp. 121–127.
Beyer, M.A., Diecke, F.P.J., Mistry, K., and Cruze, E., Pharmacology, 1997, vol. 54, pp. 76–83.
Li, Y. X., Luo, Y. P., Xi, Z., Niu, C., He, Y. Z., and Yang, G.F., J. Agric. Food Chem., 2006, vol. 54, pp. 9135–9139. https://doi.org/10.1021/jf061976j
Nagai, H., Suda, H., Iwama, T., Daikoku, M., Yanagihara, Y., and Koda, A., Int. Arch. Allergy Immunol., 1992, vol. 98, pp. 57–63. https://doi.org/10.1159/000236164
Corsano, S., Strappaghetti, G., Ferrini, R., and Giglioli, N., Arch. Pharm. (Weinheim), 1991, vol. 324, pp. 999–1001. https://doi.org/10.1002/ardp.2503241212
Alcorn, K., Ralvetgravir shows potential for use as PrEP drug. AIDSmap.com. April 2009, 28. Accessed November 8, 2009.
Mascolini, M., Merck offers unique perspective on second-generation integrase inhibitor, in 10th International Workshop on Clinical Pharmacology of HIV Therapy, April 15–17,2009, Amsterdam. Accessed November 8, 2009.
Avdulov, N.A. and Maĭsov, N.I., Biull. Eksp. Biol. Med., 1981, vol. 92, pp. 564–566.
Kazuhiro, M., Takenori, H., Takashi, I.,Satoshi, S., Mie, Y., Masami, K., Akira, T., Daisuke, N., Shuichi, F., Satoshi, E., Kazumasa, H., and Tomoyuki, K., J. Med. Chem., 2011, vol. 54, pp. 4998–5012. https://doi.org/10.1021/jm200216q
Daisuke, N., Tsuneo, M., Akira, T., Mie, Y., Yumiko, A., Mari, A., Reiko, S., Michiyasu, T., Kazuhiro, M., Tatsuya, W., and Masami, K., Eur. J. Pharmacol., 2014, vol. 723, pp. 167–174. https://doi.org/10.1016/j.ejphar.2013.12.001
Isabelle, S., Dominique de Z., Bruno, B., Pietro, S., Frédéric, B., and Charles, C., Expert Opin. Emerg. Drugs, 2012, vol. 17, pp. 83–104. https://doi.org/10.1517/14728214.2012.668885
Elancheran, R., Maruthanila, V.L., Ramanathan, M., Kabilan, S., Devi, R., Kunnumakara, A., and Kotoky, J., Med. Chem. Commun., 2015, vol. 6, pp. 746–768. https://doi.org/10.1039/C4MD00481G
Struthers, R. Scott, N., Andrew, J., Grundy, J., Chen, T., Jimenez, R., Yen, S., and Bozigian, H.P., J. Clin. Endocrinol. Metabol., 2009, vol. 94, pp. 545–551. https://doi.org/10.1210/jc.2008-1695
Yang, L., Dan, H.C., Sun, M., Liu, Q., Sun, X.M., Feldman, R.I., Hamilton, A.D., Polokoff, M., Nicosia, S.V., Herlyn, M., Sebti, S.M., and Cheng, J.Q., Cancer Res., 2004, vol. 64, pp. 4394–4399. https://doi.org/10.1158/0008-5472.CAN-04-0343
Schram, K.H. and Townsend, L.B., Tetrahedron Lett., 1971, vol. 12, pp. 4757–4760. https://doi.org/10.1016/S0040-4039(01)87546-8
Feun, L.G., Savaraj, N., Bodey, G.P., Lu, K., Yap, B.S., Ajani, J.A., Burgess, M.A., Benjamin, R.S., McKelvey, E., and Krakoff, I., Cancer Res., 2004, vol. 44, pp. 3608–3612.
Feun, L.G., Blessing, J.A., Barrett, R.J., and Hanjani, P., Am. J. Clin. Oncol., 1993, vol. 16, pp. 506–508. https://doi.org/10.1097/00000421-199312000-00010
Yang, L., Dan, H.C., Sun, M., Liu, Q., Sun, X.M., Feldman, R.I., Hamilton, A.D., Polokoff, M., Nicosia, S.V., Herlyn, M., Sebti, S.M., and Cheng, J.Q., Cancer Res., 2004, vol. 64, pp. 4394–4399. https://doi.org/10.1158/0008-5472.CAN-04-0343
Kim D., Sun M., He L., Zhou Q.H., Chen J., Sun X.M., Bepler G., Sebti S.M., Cheng J.Q. J Biol Chem. 2010, vol. 285, pp. 8383–8394. https://doi.org/10.1074/jbc.M109.094060
Berndt N., Yang H., Trinczek B., Betzi S., Zhang Z., Wu B., Lawrence N.J., Pellecchia M., Schönbrunn E., Cheng J.Q., Sebti S.M. Cell Death Differ, 2010, vol. 11, pp. 1795–1804. https://doi.org/10.1038/cdd.2010.63
Balasis, M.E., Forinash, K.D., Chen, Y.A., Fulp, W.J., Coppola, D., Hamilton, A.D., Cheng, J.Q., and Sebti, S.M., Clin. Cancer Res., 2011, vol. 17, pp. 2852–2862. https://doi.org/10.1158/1078-0432.CCR-10-2544
Kim, R., Yamauchi, T., Husain, K., Sebti, S., and Malafa, M., Anticancer Res., 2015, vol. 35, pp. 4599–4604.
Garrett, C.R., Coppola, D., Wenham, R.M., Cubitt, C.L., Neuger, A.M., Frost, T.J., Lush, R.M., Sullivan, D.M., Cheng, J.Q., and Sebti, S.M., Invest. New Drugs, 2011, vol. 29, pp. 1381–1389. https://doi.org/10.1007/s10637-010-9479-2
Triciribine phosphate monohydrate (TCN-PM, VD-0002) in adult patients with advanced hematologic malignancies. Clinicaltrials.gov. U.S. National Institutes of Health. Retrieved December 7, 2015.
Sampath, D., Malik, A., Plunkett, W., Nowak, B., Williams, B., Burton, M., Verstovsek, S., Faderl, S., Garcia-Manero, G., List, A.F., Sebti, S., Kantarjian, H.M., Ravandi, F., and Lancet, J.E., Leuk. Res., 2013, vol. 37, pp. 1461–1467. https://doi.org/10.1016/j.leukres.2013.07.034
Abd El-Ghaffar, N.F., Mohamed, M.K., Kadah, M.S., Radwan, A.M., Said, G.H., and Abdel-al, S.N., J. Chem. Pharm. Res., 2011, vol. 3, pp. 248–259.
Karahan, E., Synthesis of furopyrrolone and furopyridazinone derivatives: a new class of compounds, Thesis of Middle East Technical University, 2011.
Kellogg, R.L., Nehring, R., Grube, A., Goss, D.W., and Plotkin, S., Environmental Indicators of Pesticide Leaching and Runoff from Farm Fields, United States Department of Agriculture Natural Resources Conservation Service, 2000.
Hovakimyan, S.A., Babakhanyan, A.V., Voskanyan, V.S., Karapetian, V.E., Panosyan, G.A., and Kocharian, S.T., Chem. Heterocycl. Compd., 2004, vol. 40, p. 1047.
Laguna, R., Rodriguez-Linarez, B.,Cano, E., Estevez, I., Ravina, E., and Sotelo, E., Chem. Pharm. Bull. (Tokyo), 1997, vol. 45, pp. 1151–1155. https://doi.org/10.1248/cpb.45.1151
Fox, P., Insect Growth Regulators, PJB Publisher Ltd., 1990.
Mondal, K.A.M.S.H. and Parween, S., Integr. Pest Manage. Rev., 2000, vol. 5, pp. 255–295. https://doi.org/10.1023/A:1012901832162
Huang, Q., Qian, X., Song, G., and Cao, S., Pest Manage. Sci., 2003, vol. 59, pp. 933–939. https://doi.org/10.1002/ps.704
Qian, X., Cao, S., Li, Z., Song, G.H., and Huang, Q., Oxadiazole derivatives as novel insect-growth regulators: synthesis and structure-bioactivity relationship, in New Discoveries in Agrochemicals, Clark, J.M. and Ohkawa, H., Eds., 2005, pp. 273–282.
Cao, S., Wei, N., Zhao, C.M., Li, L.N., Huang, Q.C., and Qian, X.H., J. Agr. Food Chem., 2005, vol. 53, pp. 3120–3125. https://doi.org/10.1021/jf047985e
Schoonhoven, L.M. and Liner, L., J. Comp. Physiol., A, 1994, vol. 175, pp. 519–524.
Wu, C., Wu, H., and Lei, L. Compositions and methods for controlling pests using synergistic cocktails of plant alkaloids, US Patent, 2002, vol. 655, p. 613.
Cui, Z. and He, X., World J. Gastroenterol., 2002, vol. 8, pp. 5918–5922.
Isman, M.B., Pestic. Sci., 1991, vol. 15, pp. 39–47.
Isman, M.B., Pestic. Sci., 1993, vol. 38, pp. 57–63.
Simmons, K.A. and Halling, B.P., ACS Symp., Synth. Chem. Agrochem., 1991, vol. 443, pp. 236–246. https://doi.org/10.1021/jf0208029
Qian, X. and Zhang R., J. Chem. Technol. Biotechnol., 1996, vol. 67, pp. 124–130. https://doi.org/10.1002/(SICI)1097-4660
Shi, W., Qian, X., Zhang, R., and Song, G., J. Fluorine Chem., 2000, vol. 106, pp. 173–179.
Shi, W., Qian, X., Zhang, R., and Song, G., J. Agric. Food Chem., 2001, vol. 49, pp. 124–130. https://doi.org/10.1021/jf0007941
Miyake, T., Haruyama, H., Ogura, T., Mitsui, T., and Sakurai, A., J. Pestic. Sci. (Int. Ed.), 1992, vol. 17, pp. 75–82. https://doi.org/10.1021/jf0007941
Miyake, T., Igarashi, S., Ishii, S., Ogura, T., and Haruyama, H., in Brighton Crop Prot.Conf.—Pests Dis., 1994, vol. 1, pp. 59–66.
Taniguchi, M., Baba, M., Ochiai, Y., Hirose, M., and Hirata, K., Preparation of Insecticidal Pyridazinone Derivatives. 1990, CA 1270830.
Zou, X.J., Jin, G.Y., and Yang, Z., Chin. J. Appl. Chem., 2001, vol. 18, pp. 599–601. https://doi.org/10.1364/OL.26.000599
Zou, X.J., Jin, G.Y., and Yang, Z., Chem. J. Chin. Univ., 2002, vol. 23, pp. 404–406.
Ashour, F.A., El-Hawash, S.A.M., and Mahran, M.A., Bull. Pharm. Sci.,Assiut Univ., 1994, vol. 17, pp. 17–25.
Holla, B. S., Gonsalves, R., and Shenoy, S., Eur. J. Med. Chem., 2000, vol. 35, p. 267. https://doi.org/10.1016/s0223-5234(00)00154-9
Zou, X.J. and Jin, G.Y., Chin. Chem. Lett., 2001, vol. 12, pp. 419–420.
Zou, X.J., Jin, G.Y., and Zhang, Z.X., J. Agric. Food Chem., 2002, vol. 50, pp. 1451–1454. https://doi.org/10.1021/jf0109266
Huang, Q., Kong, Y., Liu, M., Feng, J., and Liu, Y., J. Insect Sci., 2006, vol. 8, pp. 1–7. https://doi.org/10.1109/ACCT.2014
Zou, X.J., Lai, L.H., Jin, G.Y., and Zhang, Z.X., J. Agric. Food Chem., 2002, vol. 50, pp. 3757–3760. https://doi.org/10.1021/jf0201677
Abdelbaset, M.S., Abdel-Aziz, M., Abuo-Rahma, G.E.A, Ramadan, M., and Abdelrahman, M.H., J. Adv. Biomed. Pharm. Sci., 2019, vol. 2, pp. 19–28.
Lee, J., Shin, A.Y., and Lee, H.S., Bull. Korean Chem. Soc., 2017, vol. 38, pp. 804–807. https://doi.org/10.1002/bkcs.11156
Abbas, S.H., Abuo-Rahma, G.E.-D.A., Abdel-Aziz, M., Aly, O.M., Beshr, E.A., and Gamal-Eldeen, A.M., Bioorg. Chem., 2016, vol. 66, pp. 46–62. https://doi.org/10.1016/j.bioorg.2016.03.007
Liu, Y., Jin, S., Peng, X., Lu, D., Zeng, L., Sun, Y., Ai, J., Geng, M., and Hu, Y., Eur. J. Med. Chem., 2016, vol. 108, pp. 322–333. https://doi.org/10.1016/j.ejmech.2015.11.042
Barberot, C., Moniot, A., Allart-Simon, I., Malleret, L., Yegorova, T., LaronzeCochard, M., Bentaher, A., Médebielle, M., Bouillon, J.-P., and Hénon, E., Eur. J. Med. Chem., 2018, vol. 146, pp. 139–146. https://doi.org/10.1016/j.ejmech.2018.01.035
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
COMPLIANCE WITH ETHICAL STANDARDS
This article does not contain any studies invol. ving human participants performed by any of the authors and does not contain any studies invol. ving animals performed by any of the authors.
Conflict of Interests
The authors declare that they have no conflicts of interest.
Additional information
Corresponding author: e-mail: aasif321@gmail.com.
Rights and permissions
About this article
Cite this article
Mohd Imran, Mohammad Asif Study of Various Pyridazine and Phthalazine Drugs with Diverse Therapeutical and Agrochemical Activities. Russ J Bioorg Chem 46, 745–767 (2020). https://doi.org/10.1134/S1068162020050167
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1134/S1068162020050167