van der Mers (vdMs), a unit of protein structure, facilitate de novo design of proteins that bind small molecules.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Research paper
Polizzi, N. F. & DeGrado, W. F. Science 369, 1227–1233 (2020).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Singh, A. De novo design of small-molecule-binding proteins. Nat Methods 17, 1073 (2020). https://doi.org/10.1038/s41592-020-00995-3
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41592-020-00995-3