Abstract
The fall armyworm, Spodoptera frugiperda, is a polyphagous pest that causes important damage in different regions of America and mainly affects corn crops in both tropical and subtropical areas. Currently, control relies on both transgenic plants and/or chemical pesticides. In this work, we describe insecticidal activity against the fall armyworm from a series of Mannich bases (1–10), derived from 2-hydroxy-1,4-naphthoquinone (lawsone), substituted benzaldehydes, and two primary amines, and their Cu2+ complexes (11–20). The [Cu(L)2] complexes were more effective in larval mortality compared to the free Mannich bases. Among the tested compounds, complex 11 showed the highest toxicity, with 70.00% larval mortality.
Funding source: National Council for Scientific and Technological Development
Funding source: Coordination for the Improvement of Higher Education Personnel
Funding source: Fundação de Amparo à Pesquisa do Estado de São Paulo
Author contribution: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Research funding: The authors would like to thank the National Council for Scientific and Technological Development (CNPq, grant # 403210/2016-0), Coordination for the Improvement of Higher Education Personnel (CAPES), and the National Institute of Science and Technology for Biorational Control of Insect Pests and São Paulo Research Foundation (FAPESP, Grant # 2012/25299-6) for the financial support and scholarships (CNPq).
Conflict of interest statement: The authors declare no conflicts of interest regarding this article.
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