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RETRACTED ARTICLE: A fluorescent coordination polymer for TNP detection and protection effect on cough after infection by up-regulates the activity of neuroendopeptide enzyme in respiratory tract mucosa

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This article was retracted on 01 August 2023

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Abstract

Through utilizing the mixed-ligand method, a novel coordination polymer based on Zn(II) ions as nodes was synthesized under hydrothermal condition via applying 1,4-cyclohexanedicarboxylic acid (1,4-H2chdc) and 2-(4-fluoro-phenyl)-1H-imidazo[4,5-f][1,10]phenanthroline (L), a π-electron rich ligand, as co-ligand, and its chemical formula is [Zn(1,4-chdc)(L)(H2O)]n (1). Because of its strong ambient temperature fluorescent emission and outstanding water stability, the complex 1 could be utilized as the sensitive sensor for the 2, 4, 6-trinitrophenol (TNP) via fluorescence quenching, and the constant of quenching can reach 2.794 × 105 M−1. The following experiment was further conducted to detect the treatment activity of the synthetic compound against post-infectious cough. The release of inflammatory cytokines and endopeptidase from respiratory tract mucosa was determined through enzyme linked immunosorbent assay (ELISA). Next, the fluorescent probe of DCFH-DA was utilized to detect the accumulation of ROS in the respiratory mucosal epithelial cells.

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Authors and Affiliations

  1. Geriatrics Department, Hunan Provincial People’s Hospital, Changsha, Hunan, China

    Yu Xu

  2. Changsha Health Vocational Clinical College, Changsha, Hunan, China

    Yi Guo

  3. Department of Internal Medicine, Yuelu Second People’s Hospital, Changsha, Hunan, China

    Jie Zhang

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  1. Yu Xu
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  2. Yi Guo
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  3. Jie Zhang
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Correspondence to Jie Zhang.

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This article has been retracted. Please see the retraction notice for more detail: https://doi.org/10.1007/s10965-023-03722-6

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Xu, Y., Guo, Y. & Zhang, J. RETRACTED ARTICLE: A fluorescent coordination polymer for TNP detection and protection effect on cough after infection by up-regulates the activity of neuroendopeptide enzyme in respiratory tract mucosa. J Polym Res 27, 335 (2020). https://doi.org/10.1007/s10965-020-02299-8

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  • DOI: https://doi.org/10.1007/s10965-020-02299-8

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