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Effect of Low-Intensity Blue Light Emission on Physicochemical Properties of Blood Erythrocytes in Rats under Diabetes Mellitus Conditions

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Abstract—The physicochemical characteristics of erythrocyte membranes from the peripheral whole blood of rats and the erythrocytes washed with physiological solution, using the method of acid hemolysis, under diabetes mellitus conditions and against the therapy based on low-intensity blue light emission in the visible light range have been studied. The use of low-intensity light therapy (LILT) led to a decrease in the resistance of erythrocyte membranes to the action of acid hemolytic in the control group animals. Under diabetes conditions, LILT prolonged total hemolysis and reduced the count of hemolysed erythrocytes relative to the indices in the group of animals with DM. No expressed hypoglycemic effect due to the LILT was observed in sick animals, and the content of glycolysed hemoglobin tended to decrease.

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Correspondence to N. Yefimenko.

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This study did not receive any particular grant from financial organizations in the state, commercial or noncommercial sectors.

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Conflict of interest. The authors declare that they have no conflict of interest.

Statement on the welfare of animals. The studies were based on an animal model with the observance of all norms of bioethics in working with laboratory animals.

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Translated by N. Tarasyuk

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Yefimenko, N., Liuta, M., Karmash, O. et al. Effect of Low-Intensity Blue Light Emission on Physicochemical Properties of Blood Erythrocytes in Rats under Diabetes Mellitus Conditions. Cytol. Genet. 54, 449–455 (2020). https://doi.org/10.3103/S0095452720050102

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