Abstract
Manure, soil, and vegetable samples were collected from different-sized livestock farms in Xinxiang, China. The residues of sulfadiazine, sulfamonomethoxine, and sulfamethoxazole were analyzed by high-performance liquid chromatography. The results indicated that the concentration ranges of the three total sulfonamides in manure, soil, and vegetables were 10.13–566.23 µg kg−1, 7.60–176.26 µg kg−1, and 0–32.70 µg kg−1, respectively. The mean concentrations were 219.71 µg kg−1, 70.73 µg kg−1, and 7.08 µg kg−1 for manure, soil, and vegetables, respectively. The mean concentrations in soil were lower than the ecotoxic effect trigger value (100 µg kg−1), indicating a low risk for organisms in soil. The concentrations of the three sulfonamides varied significantly in different types of vegetables and all were lower than the acceptable daily intake value (50 µg (kg day)−1). However, the potential ecotoxicity and danger to human and animal health via accumulation of the antibiotic in the food chain cannot be ignored.
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References
An J, Chen H, Wei S, Gu J (2015) Antibiotic contamination in animal manure, soil, and sewage sludge in Shenyang, northeast China. Environ Earth Sci 74(6):5077–5086
Franklin AM, Williams CF, Andrews DM et al (2016) Uptake of three antibiotics and an antiepileptic drug by wheat crops spray irrigated with wastewater treatment plant effluent. J Environ Qual 45(2):546–554
Gou M, Hu HW, Zhang YJ et al (2018) Aerobic composting reduces antibiotic resistance genes in cattle manure and the resistome dissemination in agricultural soils. Sci Total Environ 612:1300–1310
Guardo AD, Calamari D, Benfenati E et al (2008) Pharmaceuticals as environmental contaminants: modeling distribution and fate. Pharmaceuticals in the environment. Springer, Berlin, Heidelberg, pp 121–132
Hua W, Chu Y, Fang C (2017) Occurrence of veterinary antibiotics in swine manure from large-scale feedlots in Zhejiang Province, China. Bull Environ Contam Toxicol 98(4):472–477
Hu XG, Luo Y, Zhou QX et al (2008) Determination of thirteen antibiotics residues in manure by solid phase extraction and high performance liquid chromatography. Chin J Anal Chem 36(9):1162–1166
Hu X, Zhou Q, Luo Y (2010) Occurrence and source analysis of typical veterinary antibiotics in manure, soil, vegetables and groundwater from organic vegetable bases, Northern China. Environ Pollut 158(9):2992–2998
Joint FAO/WHO Expert Committee on Food Additives (2010) Residue Evaluation of Certain Veterinary Drugs, Meeting 2010-Evaluation of data on ractopamine residues in pig tissues. FAO JECFA Monographs; Food and Agriculture Organization of the United Nations: Rome, www.fao.org/docrep/012/i1618e/i1618e00.pdf (accessed 24 Nov 2013)
Karci A, Balcioglu IA (2009) Investigation of the tetracycline, sulfonamide and fluoroquinolone antimicrobial compounds in animal manure and agricultural soils in Turkey. Sci Total Environ 407(16):4652–4664
Kim SC, Yang JE, Carlson K (2010) Dissolved and colloidal fraction transport of antibiotics in soil under biotic and biotic conditions. Water Qual Res J Can 45:275–285
Kumar K, Gupta SC, Chander Y et al (2005) Antibiotic use in agriculture and its impact on the terrestrial environment. Adv Agron 87:1–54
Li C, Chen JY, Wang JH et al (2015) Occurrence of antibiotics in soils and manures from greenhouse vegetable production bases of Beijing, China and an associated risk assessment. Sci Total Environ 521–522(1):101–107
Li XD, Yu HX, Xu SS et al (2013) Uptake of three sulfonamides from contaminated soil by pakchoi cabbage. Ecotox Environ Safe 92:297–302
Li XD, Xian QM, Liu HL et al (2010) Simultaneous determination of three sulfonamides residues in vegetable by high performance liquid chromatographic method with fluorimetric detection. Chin J Anal Chem 38(3):429–431
Qiao M, Chen W, Su J et al (2012) Fate of tetracyclines in swine manure of three selected swine farms in China. J Environ Sci 24(6):1047–1052
Sarmah AK, Meyer MT, Boxall ABA (2006) A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment. Chemosphere 65(5):725–759
Shen XW (2014) The actualities investigation of the veterinary drugs use in the region of Xinxiang. Dissertation, Henan Agricultural University
Tanoue R, Sato Y, Motoyama M et al (2012) Plant uptake of pharmaceutical chemicals detected in recycled organic manure and reclaimed wastewater. J Agric Food Chem 60(41):10203–10211
Winckler C, Grafe A (2001) Use of veterinary drugs in intensive animal production: evidence for persistence of tetracycline in pig slurry. J Soils Sedim 1(2):66–70
Yang Q, Tian T, Niu T, Wang P (2017) Molecular characterization of antibiotic resistance in cultivable multidrug–resistant bacteria from livestock manure. Environ. Pollut. 229:188–198
Zhao L, Dong YH, Wang H (2010) Residues of veterinary antibiotics in manures from feedlot livestock in eight provinces of China. Sci Total Environ 408(5):1069–1075
Zhou QX, Cai Z, Zhang ZN, Liu WT (2011) Ecological remediation of hydrocarbon contaminated soils with weed plants. J Res Ecolo 2(2):97–105
Zhou QX, Hu XG (2017) Systemic stress and recovery patterns of rice roots in response to graphene oxide nanosheets. Environ Sci Technol 51(4):2022–2030
Acknowledgements
This work was supported by the National Natural Science Foundation of China (Nos. 41907349, 21906043, 31170478 and 41601333), the Technology Department of the Henan Science and Technology Fund Project (No. 202102310597).
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Jin, C., Wei, S., Sun, R. et al. The Forms, Distribution, and Risk Assessment of Sulfonamide Antibiotics in the Manure–Soil–Vegetable System of Feedlot Livestock. Bull Environ Contam Toxicol 105, 790–797 (2020). https://doi.org/10.1007/s00128-020-03010-9
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DOI: https://doi.org/10.1007/s00128-020-03010-9