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Transcatheter arterial embolization for intractable, nontraumatic bladder hemorrhage in cancer patients: a single-center experience and systematic review

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Japanese Journal of Radiology Aims and scope Submit manuscript

Abstract

Purpose

To explore the effect of transcatheter arterial embolization (TAE) in controlling intractable, nontraumatic bladder hemorrhage in cancer patients.

Materials and methods

A literature review (PubMed and EMBASE), followed by a retrospective analysis of all cancer patients with intractable hematuria from bladder treated by TAE at our tertiary referral center.

Results

At our institution, 27 consecutive cancer patients who underwent TAE for refractory hematuria from bladder were identified. The systematic review included 13 studies published between 1981 and 2019. In our local cohort, 27 patients were treated with 100% technical success, clinical success in 88.9%, no major complications, and rebleeding rate within the first month of 7.4%. In the systematic review cohort of 201 patients, there was technical success in 99.0%, clinical success in 80.9%, major complications in 5.5%, and a rebleeding rate within the first month of 4.5%. Bilateral embolization was performed in 81.1%, and embolization levels were mostly anterior division of internal iliac artery (73.7%) and vesical artery (23.2%).

Conclusion

TAE is effective and safe to control intractable hematuria from bladder origin in cancer patients after failure of conservative management, providing effective temporary hemostasis. For bladder hemorrhage unsuitable for surgery, TAE should be considered at an early stage.

Secondary abstract

A literature review, followed by retrospective analysis of all patients with intractable hematuria from bladder treated by transcatheter arterial embolization at our tertiary referral center. Transcatheter arterial embolization is effective and safe to control intractable hematuria from bladder. The major complication rate and rebleeding within the first month are acceptable.

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Author information

Author notes

  1. Chengshi Chen and Pyeong Hwa Kim contributed equally to this work and share the first authorship.

Authors and Affiliations

  1. Department of Radiology, The Affiliated Cancer Hospital of Zhengzhou University, No. 127 Dongming Road, Zhengzhou, 450008, China

    Chengshi Chen, Ji Hoon Shin & Hai-Liang Li

  2. Department of Radiology and Research Institute of Radiology, University of Ulsan, College of Medicine, Asan Medical Center, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea

    Pyeong Hwa Kim & Ji Hoon Shin

  3. Department of Radiology, Chamjoeun Hospital, Gwangju, Korea

    Ki Woong Yoon

  4. Department of Radiology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea

    Mi Sun Chung

  5. Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

    Bumsik Hong

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  1. Chengshi Chen
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Correspondence to Ji Hoon Shin.

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Chen, C., Kim, P.H., Shin, J.H. et al. Transcatheter arterial embolization for intractable, nontraumatic bladder hemorrhage in cancer patients: a single-center experience and systematic review. Jpn J Radiol 39, 273–282 (2021). https://doi.org/10.1007/s11604-020-01051-y

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  • DOI: https://doi.org/10.1007/s11604-020-01051-y

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