Neuron
Volume 107, Issue 6, 23 September 2020, Pages 990-991
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The Sound of Silence: Hidden Responses of Neural Circuits to Alzheimer-Linked Mutations

https://doi.org/10.1016/j.neuron.2020.08.016Get rights and content
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Summary

Dysfunctions of cortico-hippocampal circuits represent a hallmark of Alzheimer’s disease. In this issue of Neuron, Jun et al. illuminate the spatial coding failures by familial Alzheimer’s disease mutations that may underlie the progressive decline in spatial mnemonic processing.

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