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Effect of (co)polymers based on methacrylic acid on the state of cells of the immune system

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Abstract

A series of methacrylic acid co(polymers) were obtained using various reversible chain transfer agents. The molecular weight characteristics of the synthesized (co)polymers were determined using gel permeation chromatography. In vitro studies showed the absence of cytotoxicity of the obtained compounds against immune cells (peritoneal macrophages) and the absence of an effect on the functional activity of the cells.

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Correspondence to O. V. Zhukova.

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Based on the materials of the XXI Mendeleev Congress on General and Applied Chemistry (September 9–13, 2019, St. Petersburg, Russia).

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 8, pp. 1579–1584, August, 2020.

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Zhukova, O.V., Zaitsev, S.D., Ryabov, S.A. et al. Effect of (co)polymers based on methacrylic acid on the state of cells of the immune system. Russ Chem Bull 69, 1579–1584 (2020). https://doi.org/10.1007/s11172-020-2938-9

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  • DOI: https://doi.org/10.1007/s11172-020-2938-9

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