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Synthesis of 5-Substituted N-Nitro-2,4-dihydro-3H-1,2,4-triazol-3-imines

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Abstract

The reaction of N-amino-N″-nitroguanidine with carboxylic acid chlorides at room temperature gave the corresponding N-(N″-nitroguanidino)carboxamides which underwent cyclization on heating in aqueous alkali to afford N-nitro-1,2,4-triazol-3-imines. The latter were also synthesized in a one-pot fashion. The products were characterized by 1H and 13C–{1H}, IR, and UV spectra.

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ACKNOWLEDGMENTS

Physicochemical studies were performed at the joint center of Herzen State Pedagogical University of Russia.

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Authors and Affiliations

  1. Herzen State Pedagogical University of Russia, 19186, St. Petersburg, Russia

    O. Yu. Ozerova, T. P. Efimova & T. A. Novikova

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  1. O. Yu. Ozerova
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  2. T. P. Efimova
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  3. T. A. Novikova
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Correspondence to O. Yu. Ozerova.

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To the 80th anniversary of V.M. Berestovitskaya

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Ozerova, O.Y., Efimova, T.P. & Novikova, T.A. Synthesis of 5-Substituted N-Nitro-2,4-dihydro-3H-1,2,4-triazol-3-imines. Russ J Gen Chem 90, 1403–1407 (2020). https://doi.org/10.1134/S1070363220080046

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