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Efficient Synthesis of 1,4-Bis(5-aryl-1,3,4-oxadiazol-2-yl)-2,3,5,6-tetrafluorobenzenes

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Abstract

An efficient acid-catalyzed condensation between substituted benzohydrazides and 2,3,5,6-tetrafluoroterephthalic acid to form 1,4-bis(5-aryl-1,3,4-oxadiazol-2-yl)-2,3,5,6-tetrafluorobenzenes is reported. The products were isolated in 74–87% yield and were characterized by 1H NMR, IR, and mass spectra.

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ACKNOWLEDGMENTS

We are thankful to Principal, Maulana Azad College, Aurangabad, and Principal, Swami Vivekanand College Mantha, for providing research facilities. We also thank SAIF Punjab University, Chandigarh and SAIF Shillong for providing the spectral and analytical data.

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Authors and Affiliations

  1. Swami Vivekanand Sr. College, 431504, Mantha, India

    B. K. Dhotre

  2. Maulana Azad College and Research Center Rouza Bagh, 431001, Aurangabad, India

    S. V. Raut & A. Pathan

  3. Department of Chemistry, J. E. S. College, 431203, Jalna, India

    A. U. Khandebharad

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  1. B. K. Dhotre
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  2. S. V. Raut
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  3. A. U. Khandebharad
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  4. A. Pathan
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Correspondence to B. K. Dhotre.

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Dhotre, B.K., Raut, S.V., Khandebharad, A.U. et al. Efficient Synthesis of 1,4-Bis(5-aryl-1,3,4-oxadiazol-2-yl)-2,3,5,6-tetrafluorobenzenes. Russ J Org Chem 56, 1324–1326 (2020). https://doi.org/10.1134/S1070428020070313

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