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Three-Component Reaction of 1,3,4,6-Tetraketones with Acetone and Amines

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Abstract

1,6-Diarylhexane-1,3,4,6-tetraones reacted with 2-aminophenol and acetone according to previously unknown pathway leading to the formation of 3-aryl-3-hydroxy-1-{5-[(2-hydroxyphenyl)amino][1,1′-biphenyl]-3-yl}prop-2-en-1-ones. Similar three-component reactions with benzylamine or 2-methoxyaniline afforded mainly 2-(4-aroyl-3-hydroxy-5,5-dimethyl-1,5-dihydro-2H-pyrrol-2-ylidene)-1-arylethan-1-ones.

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Funding

This study was performed under financial support by the Russian Foundation for Basic Research (project no. 18-33-01084 mol_a) and by the Government of Perm Krai.

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Authors and Affiliations

  1. Perm State University, 614990, Perm, Russia

    A. R. Galeev, I. G. Mokrushin, M. V. Dmitriev & A. N. Maslivets

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  1. A. R. Galeev
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  2. I. G. Mokrushin
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  3. M. V. Dmitriev
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  4. A. N. Maslivets
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Correspondence to A. N. Maslivets.

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Galeev, A.R., Mokrushin, I.G., Dmitriev, M.V. et al. Three-Component Reaction of 1,3,4,6-Tetraketones with Acetone and Amines. Russ J Org Chem 56, 1317–1320 (2020). https://doi.org/10.1134/S1070428020070295

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