Skip to main content
Log in

Treatment of CML-transformed B Cell Acute Lymphoblastic Leukemia (B-ALL) in Adults with Anti-CD19 Chimeric Antigen Receptor T Cell (CAR T) Therapy

  • Published:
Stem Cell Reviews and Reports Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Calabretta, B., & Perrotti, D. (2004). The biology of CML blast crisis. Blood, 103(11), 4010–4022. https://doi.org/10.1182/blood-2003-12-4111.

    Article  PubMed  CAS  Google Scholar 

  2. Haferlach, T., Winkemann, M., Ramm-Petersen, L., Meeder, M., Schoch, R., Weber-Matthiesen, K., … Loffler, H. (1997). New insights into the biology of Philadelphia-chromosome-positive acute lymphoblastic leukaemia using a combination of May-Grunwald-Giemsa staining and fluorescence in situ hybridization techniques at the single cell level. British Journal of Haematology, 99(2), 452–459. https://doi.org/10.1046/j.1365-2141.1997.4203237.x.

    Article  PubMed  CAS  Google Scholar 

  3. Anastasi, J., Feng, J., Dickstein, J. I., Le Beau, M. M., Rubin, C. M., Larson, R.A., … Vardiman, J. W. (1996). Lineage involvement by BCR/ABL in Ph + lymphoblastic leukemias: chronic myelogenous leukemia presenting in lymphoid blast vs Ph + acute lymphoblastic leukemia. Leukemia, 10(5), 795–802. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/8656674.

  4. Terwilliger, T., & Abdul-Hay, M. (2017). Acute lymphoblastic leukemia: a comprehensive review and 2017 update. Blood Cancer Journal, 7(6), e577. https://doi.org/10.1038/bcj.2017.53.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  5. Holyoake, T. L., & Vetrie, D. (2017). The chronic myeloid leukemia stem cell: stemming the tide of persistence. Blood, 129(12), 1595–1606. https://doi.org/10.1182/blood-2016-09-696013.

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgements

We thank the Patient and his family and clinical trial team at the General Hospital of Western Threater Command for understanding and support. The pilot study was approved by the Institutional Review Board (clinical trial registration number NCT04156243)

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Fang Liu or William Tse.

Ethics declarations

Declarations of Interest

None.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Liu, F., Sha, S., Ma, G. et al. Treatment of CML-transformed B Cell Acute Lymphoblastic Leukemia (B-ALL) in Adults with Anti-CD19 Chimeric Antigen Receptor T Cell (CAR T) Therapy. Stem Cell Rev and Rep 16, 1356–1358 (2020). https://doi.org/10.1007/s12015-020-10008-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12015-020-10008-7

Navigation