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Can artificial neural replicators be useful for studying RNA replicators?

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Abstract

Here, I discuss the usefulness of the application of special artificial neural systems – neural replicators – to study viroids – small pathogens that are short replicating RNA sequences. Using special representations of nucleotide sequences in the form of two sequences with binary components – these two sequences are incomplete representations of the same nucleotide sequence – I show that these neural systems of different sizes are replicated in a special way on them. This allows us to extract some useful information about viroids and their structure, motifs, and relationships. This study is only the first attempt to use neural replicators to analyze genetic data.

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Acknowledgements

I am very grateful to Professor Marc H. V. van Regenmortel for his support and advice, as well as to Dr. Vladimir R. Chechetkin and Dr. Yakov B. Kazanovich for their careful and critical reading of the manuscript and for their very important suggestions for improving it. I also thank Dmitry A. Mazalov for help in preparing the final version of the manuscript.

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  1. State Research Center of Russian Federation Troitsk Institute for Innovation and Fusion Research, ul Pushkovykh 12, 108840, Troitsk, Moscow, Russia

    Alexandr A. Ezhov

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Ezhov, A.A. Can artificial neural replicators be useful for studying RNA replicators?. Arch Virol 165, 2513–2529 (2020). https://doi.org/10.1007/s00705-020-04779-0

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