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Good long-term survival and patient-reported outcomes after high tibial osteotomy for medial compartment osteoarthritis

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Knee Surgery, Sports Traumatology, Arthroscopy Aims and scope

Abstract

The lateral closing and medial opening wedge high tibial osteotomy can correct a varus malalignment of the knee caused by medial compartment osteoarthritis. These procedures have produced great short-term and mid-term results. As no systematic review has examined their long-term results yet, the goal of this article was to compare the results of all articles about lateral closing and medial opening wedge high tibial osteotomies, published after the year 2000, with a mean follow-up of more than 10 years. A systematic search of the Medline, Web of Science and Cochrane databases resulted in the inclusion of 30 articles. All these studies combined examined the results of 7087 high tibial osteotomies in a total of 6636 patients after a mean follow-up of more than 10 years. Primary outcome measures were the survival rate of the osteotomy, functional scores, patient satisfaction and pain scores. Secondary outcome measures were alignment correction and the identification of factors influencing the survival of the osteotomy. The 5-year, 10-year, 15-year and 20-year survival rates, respectively, ranged from 86 to 100%, 64–97.6%, 44–93.2% and 46–85.1%. The subjective scoring systems showed an improvement postoperatively that was maintained until final follow-up. The anatomical and mechanical tibiofemoral axis were, respectively, corrected to a mean of 7.3°–13.8° of valgus and 0.6°–4° of valgus. The results of the articles evaluating the influence of potential risk factors were contradictory. Despite the low quality of the available evidence, the lateral closing and medial opening wedge high tibial osteotomy seem to remain valid long-term treatment options for patients with painful varus malalignment caused by isolated medial compartment osteoarthritis of the knee. The available results indicate that the need for arthroplasty could be delayed for more than 15 years in the majority of patients. However, higher-quality studies are needed to confirm these findings. As a systematic review is assigned a level of evidence equivalent to the lowest level of evidence used from the analyzed manuscripts, the level of evidence of this systematic review is IV.

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References

  1. Akizuki S, Shibakawa A, Takizawa T, Yamazaki I, Horiuchi H (2008) The long-term outcome of high tibial osteotomy: a ten- to 20-year follow-up. J Bone Jt Surg Br 90:592–596

    Article  CAS  Google Scholar 

  2. Amendola A, Bonasia DE (2010) Results of high tibial osteotomy: review of the literature. Int Orthop 34:155–160

    Article  PubMed  Google Scholar 

  3. Andriacchi TP (1994) Dynamics of knee malalignment. Orthop Clin North Am 25:395–403

    Article  CAS  PubMed  Google Scholar 

  4. Benzakour T, Hefti A, Lemseffer M, El Ahmadi JD, Bouyarmane H, Benzakour A (2010) High tibial osteotomy for medial osteoarthritis of the knee: 15 years follow-up. Int Orthop 34:209–215

    Article  PubMed  PubMed Central  Google Scholar 

  5. Berman AT, Bosacco SJ, Kirshner S, Avolio A Jr (1991) Factors influencing long-term results in high tibial osteotomy. Clin Orthop Relat Res 272:192–198

    Google Scholar 

  6. Berruto M, Maione A, Tradati D, Ferrua P, Uboldi FM, Usellini E (2020) Closing-wedge high tibial osteotomy, a reliable procedure for osteoarthritic varus knee. Knee Surg Sports Traumatol Arthrosc. https://doi.org/10.1007/s00167-020-05890-0

    Article  PubMed  Google Scholar 

  7. Bode G, von Heyden J, Pestka J, Schmal H, Salzmann G, Sudkamp N et al (2015) Prospective 5-year survival rate data following open-wedge valgus high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 23:1949–1955

    Article  PubMed  Google Scholar 

  8. Bruni D, Iacono F, Akkawi I, Gagliardi M, Zaffagnini S, Marcacci M (2013) Unicompartmental knee replacement: a historical overview. Joints 1:45–47

    PubMed  PubMed Central  Google Scholar 

  9. Choi HR, Hasegawa Y, Kondo S, Shimizu T, Ida K, Iwata H (2001) High tibial osteotomy for varus gonarthrosis: a 10- to 24-year follow-up study. J Orthop Sci 6:493–497

    Article  CAS  PubMed  Google Scholar 

  10. Cooke D, Scudamore A, Li J, Wyss U, Bryant T, Costigan P (1997) Axial lower-limb alignment: comparison of knee geometry in normal volunteers and osteoarthritis patients. Osteoarthr Cartil 5:39–47

    Article  CAS  Google Scholar 

  11. Coventry MB (1965) Osteotomy of the upper portion of the tibia for degenerative arthritis of the knee. a preliminary report. J Bone Jt Surg Am 47:984–990

    Article  CAS  Google Scholar 

  12. Coventry MB, Ilstrup DM, Wallrichs SL (1993) Proximal tibial osteotomy. a critical long-term study of eighty-seven cases. J Bone Jt Surg Am 75:196–201

    Article  CAS  Google Scholar 

  13. Debeyre J, Patte D (1962) Value of corrective osteotomies in the treatment of certain knee diseases with axial deviation. Rev Rhum Mal Osteoartic 29:722–729

    CAS  PubMed  Google Scholar 

  14. Duivenvoorden T, Brouwer RW, Baan A, Bos PK, Reijman M, Bierma-Zeinstra SM et al (2014) Comparison of closing-wedge and opening-wedge high tibial osteotomy for medial compartment osteoarthritis of the knee: a randomized controlled trial with a six-year follow-up. J Bone Jt Surg Am 96:1425–1432

    Article  CAS  Google Scholar 

  15. Duivenvoorden T, van Diggele P, Reijman M, Bos PK, van Egmond J, Bierma-Zeinstra SMA et al (2017) Adverse events and survival after closing- and opening-wedge high tibial osteotomy: a comparative study of 412 patients. Knee Surg Sports Traumatol Arthrosc 25:895–901

    Article  CAS  PubMed  Google Scholar 

  16. Efe T, Ahmed G, Heyse TJ, Boudriot U, Timmesfeld N, Fuchs-Winkelmann S et al (2011) Closing-wedge high tibial osteotomy: survival and risk factor analysis at long-term follow up. BMC Musculoskelet Disord 12:46

    Article  PubMed  PubMed Central  Google Scholar 

  17. Felson DT, Zhang Y, Hannan MT, Naimark A, Weissman BN, Aliabadi P et al (1995) The incidence and natural history of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study. Arthritis Rheum 38:1500–1505

    Article  CAS  PubMed  Google Scholar 

  18. Flamme CH, Ruhmann O, Schmolke S, Wichmann R (2003) Long-term outcome following high tibial osteotomy with tension bend principle. Arch Orthop Trauma Surg 123:12–16

    Article  PubMed  Google Scholar 

  19. Flecher X, Parratte S, Aubaniac JM, Argenson JN (2006) A 12–28-year followup study of closing wedge high tibial osteotomy. Clin Orthop Relat Res 452:91–96

    Article  PubMed  Google Scholar 

  20. Gstottner M, Pedross F, Liebensteiner M, Bach C (2008) Long-term outcome after high tibial osteotomy. Arch Orthop Trauma Surg 128:111–115

    Article  PubMed  Google Scholar 

  21. Hantes ME, Natsaridis P, Koutalos AA, Ono Y, Doxariotis N, Malizos KN (2018) Satisfactory functional and radiological outcomes can be expected in young patients under 45 years old after open wedge high tibial osteotomy in a long-term follow-up. Knee Surg Sports Traumatol Arthrosc 26:3199–3205

    Article  PubMed  Google Scholar 

  22. Hernigou P, Ma W (2001) Open wedge tibial osteotomy with acrylic bone cement as bone substitute. Knee 8:103–110

    Article  CAS  PubMed  Google Scholar 

  23. Hernigou P, Medevielle D, Debeyre J, Goutallier D (1987) Proximal tibial osteotomy for osteoarthritis with varus deformity. a ten to thirteen-year follow-up study. J Bone Jt Surg Am 69:332–354

    Article  CAS  Google Scholar 

  24. Hernigou P, Roussignol X, Flouzat-Lachaniette CH, Filippini P, Guissou I, Poignard A (2010) Opening wedge tibial osteotomy for large varus deformity with Ceraver resorbable beta tricalcium phosphate wedges. Int Orthop 34:191–199

    Article  PubMed  Google Scholar 

  25. Huang TL, Tseng KF, Chen WM, Lin RM, Wu JJ, Chen TH (2005) Preoperative tibiofemoral angle predicts survival of proximal tibia osteotomy. Clin Orthop Relat Res. https://doi.org/10.1097/01.blo.0000149818.70975.07188-195

    Article  PubMed  Google Scholar 

  26. Hui C, Salmon LJ, Kok A, Williams HA, Hockers N, van der Tempel WM et al (2011) Long-term survival of high tibial osteotomy for medial compartment osteoarthritis of the knee. Am J Sports Med 39:64–70

    Article  PubMed  Google Scholar 

  27. Insall JN, Joseph DM, Msika C (1984) High tibial osteotomy for varus gonarthrosis. A long-term follow-up study. J Bone Jt Surg Am 66:1040–1048

    Article  CAS  Google Scholar 

  28. Koshino T, Wada S, Ara Y, Saito T (2003) Regeneration of degenerated articular cartilage after high tibial valgus osteotomy for medial compartmental osteoarthritis of the knee. Knee 10:229–236

    Article  PubMed  Google Scholar 

  29. Koshino T, Yoshida T, Ara Y, Saito I, Saito T (2004) Fifteen to twenty-eight years’ follow-up results of high tibial valgus osteotomy for osteoarthritic knee. Knee 11:439–444

    Article  PubMed  Google Scholar 

  30. Kuwashima U, Okazaki K, Iwasaki K, Akasaki Y, Kawamura H, Mizu-Uchi H et al (2019) Patient reported outcomes after high tibial osteotomy show comparable results at different ages in the mid-term to long-term follow-up. J Orthop Sci 24:855–860

    Article  PubMed  Google Scholar 

  31. Liu JN, Agarwalla A, Gomoll AH (2019) High tibial osteotomy and medial meniscus transplant. Clin Sports Med 38:401–416

    Article  PubMed  Google Scholar 

  32. Majima T, Yasuda K, Katsuragi R, Kaneda K (2000) Progression of joint arthrosis 10 to 15 years after high tibial osteotomy. Clin Orthop Relat Res. https://doi.org/10.1097/00003086-200012000-00021177-184

    Article  PubMed  Google Scholar 

  33. Morrison JB (1970) The mechanics of the knee joint in relation to normal walking. J Biomech 3:51–61

    Article  CAS  PubMed  Google Scholar 

  34. Naudie D, Bourne RB, Rorabeck CH, Bourne TJ (1999) The install award. Survivorship of the high tibial valgus osteotomy. A 10- to -22-year followup study. Clin Orthop Relat Res 367:18–27

    Article  Google Scholar 

  35. Niinimaki TT, Eskelinen A, Mann BS, Junnila M, Ohtonen P, Leppilahti J (2012) Survivorship of high tibial osteotomy in the treatment of osteoarthritis of the knee: finnish registry-based study of 3195 knees. J Bone Jt Surg Br 94:1517–1521

    Article  CAS  Google Scholar 

  36. Omori G, Koga Y, Miyao M, Takemae T, Sato T, Yamagiwa H (2008) High tibial osteotomy using two threaded pins and figure-of-eight wiring fixation for medial knee osteoarthritis: 14 to 24 years follow-up results. J Orthop Sci 13:39–45

    Article  PubMed  Google Scholar 

  37. Oswald MH, Jakob RP, Schneider E, Hoogewoud HM (1993) Radiological analysis of normal axial alignment of femur and tibia in view of total knee arthroplasty. J Arthroplasty 8:419–426

    Article  CAS  PubMed  Google Scholar 

  38. Papachristou G, Plessas S, Sourlas J, Levidiotis C, Chronopoulos E, Papachristou C (2006) Deterioration of long-term results following high tibial osteotomy in patients under 60 years of age. Int Orthop 30:403–408

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  39. Pfahler M, Lutz C, Anetzberger H, Maier M, Hausdorf J, Pellengahr C et al (2003) Long-term results of high tibial osteotomy for medial osteoarthritis of the knee. Acta Chir Belg 103:603–606

    Article  CAS  PubMed  Google Scholar 

  40. Polat G, Balci HI, Cakmak MF, Demirel M, Sen C, Asik M (2017) Long-term results and comparison of the three different high tibial osteotomy and fixation techniques in medial compartment arthrosis. J Orthop Surg Res 12:44

    Article  PubMed  PubMed Central  Google Scholar 

  41. Saragaglia D, Blaysat M, Inman D, Mercier N (2011) Outcome of opening wedge high tibial osteotomy augmented with a Biosorb(R) wedge and fixed with a plate and screws in 124 patients with a mean of ten years follow-up. Int Orthop 35:1151–1156

    Article  PubMed  Google Scholar 

  42. Schallberger A, Jacobi M, Wahl P, Maestretti G, Jakob RP (2011) High tibial valgus osteotomy in unicompartmental medial osteoarthritis of the knee: a retrospective follow-up study over 13–21 years. Knee Surg Sports Traumatol Arthrosc 19:122–127

    Article  PubMed  Google Scholar 

  43. Schuster P, Gesslein M, Schlumberger M, Mayer P, Mayr R, Oremek D et al (2018) Ten-year results of medial open-wedge high tibial osteotomy and chondral resurfacing in severe medial osteoarthritis and varus malalignment. Am J Sports Med 46:1362–1370

    Article  PubMed  Google Scholar 

  44. Sharma L, Song J, Dunlop D, Felson D, Lewis CE, Segal N et al (2010) Varus and valgus alignment and incident and progressive knee osteoarthritis. Ann Rheum Dis 69:1940–1945

    Article  PubMed  Google Scholar 

  45. Smith TO, Sexton D, Mitchell P, Hing CB (2011) Opening- or closing-wedged high tibial osteotomy: a meta-analysis of clinical and radiological outcomes. Knee 18:361–368

    Article  CAS  PubMed  Google Scholar 

  46. Song SJ, Bae DK, Kim KI, Park CH (2019) Long-term survival is similar between closed-wedge high tibial osteotomy and unicompartmental knee arthroplasty in patients with similar demographics. Knee Surg Sports Traumatol Arthrosc 27:1310–1319

    Article  PubMed  Google Scholar 

  47. Spahn G, Kirschbaum S, Kahl E (2006) Factors that influence high tibial osteotomy results in patients with medial gonarthritis: a score to predict the results. Osteoarthr Cartil 14:190–195

    Article  CAS  Google Scholar 

  48. Sprenger TR, Doerzbacher JF (2003) Tibial osteotomy for the treatment of varus gonarthrosis. Survival and failure analysis to twenty-two years. J Bone Jt Surg Am 85:469–474

    Article  Google Scholar 

  49. Sterne JA, Hernan MA, Reeves BC, Savovic J, Berkman ND, Viswanathan M et al (2016) ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ 355:i4919

    Article  PubMed  PubMed Central  Google Scholar 

  50. Trieb K, Grohs J, Hanslik-Schnabel B, Stulnig T, Panotopoulos J, Wanivenhaus A (2006) Age predicts outcome of high-tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 14:149–152

    Article  CAS  PubMed  Google Scholar 

  51. van Raaij T, Reijman M, Brouwer RW, Jakma TS, Verhaar JN (2008) Survival of closing-wedge high tibial osteotomy: good outcome in men with low-grade osteoarthritis after 10–16 years. Acta Orthop 79:230–234

    Article  PubMed  Google Scholar 

  52. van Wulfften Palthe AFY, Clement ND, Temmerman OPP, Burger BJ (2018) Survival and functional outcome of high tibial osteotomy for medial knee osteoarthritis: a 10–20-year cohort study. Eur J Orthop Surg Traumatol 28:1381–1389

    Article  PubMed  Google Scholar 

  53. W-Dahl A, Robertsson O, Lohmander LS (2012) High tibial osteotomy in Sweden, 1998–2007: a population-based study of the use and rate of revision to knee arthroplasty. Acta Orthop 83:244–248

    Article  PubMed  PubMed Central  Google Scholar 

  54. Wang Z, Zeng Y, She W, Luo X, Cai L (2018) Is opening-wedge high tibial osteotomy superior to closing-wedge high tibial osteotomy in treatment of unicompartmental osteoarthritis? A meta-analysis of randomized controlled trials. Int J Surg 60:153–163

    Article  PubMed  Google Scholar 

  55. Webb M, Dewan V, Elson D (2018) Functional results following high tibial osteotomy: a review of the literature. Eur J Orthop Surg Traumatol 28:555–563

    Article  PubMed  PubMed Central  Google Scholar 

  56. Wong KL, Lee KB, Tai BC, Law P, Lee EH, Hui JH (2013) Injectable cultured bone marrow-derived mesenchymal stem cells in varus knees with cartilage defects undergoing high tibial osteotomy: a prospective, randomized controlled clinical trial with 2 years’ follow-up. Arthroscopy 29:2020–2028

    Article  PubMed  Google Scholar 

  57. Wright J, Heck D, Hawker G, Dittus R, Freund D, Joyce D et al (1995) Rates of tibial osteotomies in Canada and the United States. Clin Orthop Relat Res 319:266–275

    Google Scholar 

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Ollivier, B., Berger, P., Depuydt, C. et al. Good long-term survival and patient-reported outcomes after high tibial osteotomy for medial compartment osteoarthritis. Knee Surg Sports Traumatol Arthrosc 29, 3569–3584 (2021). https://doi.org/10.1007/s00167-020-06262-4

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