Abstract
This study analyzed the characteristics of pursuit and assessed the influence of prior and visual information on eye velocity and saccades in amblyopic and control children, in comparison to adults. Eye movements of 41 children (21 amblyopes and 20 controls) were compared to eye movements of 55 adults (18 amblyopes and 37 controls). Participants were asked to pursue a target moving at a constant velocity. The target was either a ‘standard’ target, with a uniform color intensity, or a ‘noisy’ target, with blurry edges, to mimic the blurriness of an amblyopic eye. Analysis of pursuit patterns showed that the onset was delayed, and the gain was decreased in control children with a noisy target in comparison to amblyopic or control children with a standard target. Furthermore, a significant effect of prior and visual information on pursuit velocity and saccades was found across all participants. Moreover, the modulation of the effect of visual information on the pursuit velocity by group, that is amblyopes or controls with a standard target, and controls with a noisy target, was more limited in children. In other words, the effect of visual information was higher in control adults with a standard target compared to control children with the same target. However, in the case of a blurry target, either in control participants with a noisy target or in amblyopic participants with a standard target, the effect of visual information was larger in children.
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The research protocol followed the tenets of the Declaration of Helsinki and was approved by the University of Louvain’s Human Biomedical Ethics Board. All participants and, in the case of children, their carers provided informed written consent before participating in the study.
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Hemptinne, C., Deravet, N., Orban de Xivry, JJ. et al. Influence of prior and visual information on eye movements in amblyopic children. J Comput Neurosci 49, 333–343 (2021). https://doi.org/10.1007/s10827-020-00764-3
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DOI: https://doi.org/10.1007/s10827-020-00764-3