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Prevalence and epidemiological characteristics of human immunodeficiency virus-1 infection in an iron mining area with intense migratory flow in Pará State, Brazilian amazon, 2005–2014

  • Clinical Microbiology - Research Paper
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Abstract

Acquired immunodeficiency syndrome (AIDS) caused by human immunodeficiency virus (HIV) is a major global public health problem. The aim of this study is to determine the prevalence of HIV-1 infection in four municipalities of Pará State (Marabá, Parauapebas, Curionópolis, and Canaã dos Carajás), in northern, Brazil. The municipalities are located in the Carajás Complex iron mining area. The employment opportunities result in extensive migratory flow of people. A total of 4771 serum samples were obtained from 2005 to 2014 and were sent to Evandro Chagas Institute, Belém-Pará, where they were tested by enzyme-linked immunosorbent assay, with reactive samples confirmed by Western blot analysis. The samples were from individuals from 23 Brazilian states and the Federal District, mainly Maranhão (39.53%) and other municipalities of Pará (34.25%). The total positivity rate was 0.48% (23/4771). The rate was 0.47% (14/2975) in males and 0.50% (9/1796) in females. Of these, 0.33% (14/4275) were from asymptomatic individuals whose serum were collected during the serological survey, 1.81% (9/497) were from cases featuring clinical symptoms including fever/diarrhea/jaundice, which were included in febrile, diarrheal, and icteric syndromes analyzed during the study. The findings indicated the presence of HIV-1 infection in the general population studied. The majority of cases (60.9%, 14 of 23 positive cases) were asymptomatic.

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Acknowledgments

We are grateful to Sr. Lindomar Vasconcelos and the entire field staff that helped with the collection of serum samples and clinical data used in the present study. We thank the valuable technical support provided by Celina Freitas and Dielle Teixeira; as well as the Geoprocessing Laboratory (LABGEO), especially to the technician Clístenes Pamplona Catete, for the elaboration of the mapping of the study region, and Sr. Afonso Alves for spreadsheet. Special thanks to all the persons who participated in this study.

Funding

This research was supported by Vale do Rio Doce Company and Evandro Chagas Institute (IEC), and the payment of English review was done by the Virology Pós-Graduation Program of IEC.

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Authors and Affiliations

  1. Seção de Virologia/Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde, Rodovia BR-316 km 7 s/n, Levilândia,, Ananindeua, Pará, 67030-000, Brazil

    Olinda Macêdo, Felipe Bonfim Freitas, Raimundo Macedo dos Reis, Jones Anderson Monteiro Siqueira & Yvone Benchimol Gabbay

  2. Seção de Hepatologia /Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde,, Rodovia BR-316 Km 7 s/n, Levilândia, Ananindeua, Pará, 67030-000, Brazil

    Gilberta Bensabath & Heloisa Marciliano Nunes

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  1. Olinda Macêdo
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  2. Felipe Bonfim Freitas
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  3. Raimundo Macedo dos Reis
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  4. Gilberta Bensabath
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  5. Heloisa Marciliano Nunes
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  6. Jones Anderson Monteiro Siqueira
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  7. Yvone Benchimol Gabbay
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Correspondence to Yvone Benchimol Gabbay.

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Macêdo, O., Freitas, F.B., dos Reis, R.M. et al. Prevalence and epidemiological characteristics of human immunodeficiency virus-1 infection in an iron mining area with intense migratory flow in Pará State, Brazilian amazon, 2005–2014. Braz J Microbiol 51, 1737–1745 (2020). https://doi.org/10.1007/s42770-020-00361-7

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  • DOI: https://doi.org/10.1007/s42770-020-00361-7

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