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Bovine papular stomatitis virus and pseudocowpox virus coinfection in dairy calves in Japan

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Abstract

Two cases of coinfection with bovine papular stomatitis virus (BPSV) and pseudocowpox virus (PCPV) in dairy calves in Tochigi Prefecture, Japan, are reported. Sequences of BPSV and PCPV were simultaneously detected in the same polymerase chain reaction (PCR) amplicons, which were obtained from the DNA of two dairy calves using a pan-parapoxvirus primer set. PCR amplification using BPSV- and PCPV-specific primer sets were able to distinguish between the two viruses in coinfected clinical samples. Based on these data, further studies on the occurrence BPSV/PCPV coinfections in cattle in Japan are warranted.

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Availability of data and material

All data generated or analyzed during this study are included in this published article and its supplementary information files. The sequence data obtained in this study are available from DDBJ/EMBL/GenBank (accession nos. LC523626–LC523629).

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Acknowledgements

We would like to acknowledge Tochigi Central Livestock Hygiene Service Center, Japan, for providing samples from calves, the Laboratory of Veterinary Microbiology (Gifu University, Japan) for providing Madin-Darby bovine kidney cells, and Dr. Hisashi Aso (Tohoku University, Japan) for providing bovine intestinal epithelial cells.

Funding

This study was partly supported by the Grant for Joint Research Program of the Research Center for Zoonosis Control, Hokkaido University, from the Ministry of Education, Culture, Sports, Science and Technology, Japan. This study was also supported in part by a research grant from the Okawa Foundation for Information and Telecommunications, and by a grant for environmental research projects from the Sumitomo Foundation.

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Authors and Affiliations

  1. Laboratory of Food and Environmental Hygiene, Cooperative Department of Veterinary Medicine, Gifu University, Gifu, Japan

    Kaori Shimizu, Yassien Badr, Ayaka Okada & Yasuo Inoshima

  2. Department of Animal Medicine (Infectious Diseases), Faculty of Veterinary Medicine, Damanhour University, El-Beheira, Egypt

    Yassien Badr

  3. Education and Research Center for Food Animal Health, Gifu University (GeFAH), Gifu, Japan

    Ayaka Okada & Yasuo Inoshima

  4. The United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan

    Yasuo Inoshima

  5. Joint Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan

    Yasuo Inoshima

Authors
  1. Kaori Shimizu
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  2. Yassien Badr
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  3. Ayaka Okada
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  4. Yasuo Inoshima
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Contributions

KS and YI analyzed all the data and were the major contributors to the writing of the manuscript. KS, YB, and AO performed nucleotide sequencing and phylogenetic analysis. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Yasuo Inoshima.

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The authors declare that they have no conflict of interest.

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Shimizu, K., Badr, Y., Okada, A. et al. Bovine papular stomatitis virus and pseudocowpox virus coinfection in dairy calves in Japan. Arch Virol 165, 2659–2664 (2020). https://doi.org/10.1007/s00705-020-04792-3

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  • DOI: https://doi.org/10.1007/s00705-020-04792-3

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