RSV M2-1 Protein in Complex with RNA: Old Questions Are Answered and a New One Emerges

doi:10.1016/j.str.2020.08.007

Structure

Volume 28, Issue 9, 1 September 2020, Pages 977-978

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The respiratory syncytial virus (RSV) M2-1 protein is essential for virus transcription. In this issue of Structure, Gao et al. (2020) describe the crystal structure of M2-1 in complex with RNA. This structure provides new insight into the RSV transcription mechanism but also raises an intriguing question regarding M2-1’s function.

Keywords

respiratory syncytial virus

human metapneumovirus

non-segmented negative strand RNA virus

RNA-dependent RNA polymerase

M2-1 protein

transcription

Structure

PreviewRSV M2-1 Protein in Complex with RNA: Old Questions Are Answered and a New One Emerges

Keywords

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RSV M2-1 Protein in Complex with RNA: Old Questions Are Answered and a New One Emerges