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MR imaging findings for differentiating nonhemophilic hemosiderotic synovitis from diffuse-type tenosynovial giant cell tumor of the knee

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Abstract

Purpose

To evaluate the differences in MR findings between nonhemophilic hemosiderotic synovitis (HS) and diffuse-type tenosynovial giant cell tumor (D-TGCT) of the knee.

Methods

This study included 13 patients with histopathologically confirmed intra-articular hemosiderin deposition of the knee (eight with nonhemophilic HS and five with D-TGCT) who underwent preoperative MR imaging including T2*-weighted images (T2*WI). We retrospectively reviewed the MR images and compared MR findings between the two pathologies.

Results

Lateral meniscus tear and lateral articular cartilage injury (88% vs. 20%, p < 0.05) and distribution in the suprapatellar bursa of the maximum thickness of T2* hypointense synovium (75% vs. 0%, p < 0.05) were significantly more frequent in nonhemophilic HS than in D-TGCT, respectively. Among patients who underwent contrast-enhanced imaging, all five patients with nonhemophilic HS showed minimal to mild enhancement of the thickened synovium with superficial linear enhancement, whereas all four patients with D-TGCT showed moderate to severe enhancement (p < 0.01).

Conclusion

As compared with D-TGCT, lateral meniscus tear, lateral articular cartilage injury, lesser degree of contrast enhancement of the thickened synovium, and distribution in the suprapatellar bursa of the maximum thickness of T2* hypointense synovium were characteristic features of nonhemophilic HS.

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Authors and Affiliations

  1. Department of Radiology, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan

    Tomohiro Ando, Hiroki Kato, Masaya Kawaguchi, Fuminori Hyodo & Masayuki Matsuo

  2. Department of Orthopedic Surgery, Gifu University, Gifu, Japan

    Akihito Nagano

Authors
  1. Tomohiro Ando
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  2. Hiroki Kato
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  3. Masaya Kawaguchi
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  4. Akihito Nagano
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  5. Fuminori Hyodo
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  6. Masayuki Matsuo
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Correspondence to Hiroki Kato.

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Ando, T., Kato, H., Kawaguchi, M. et al. MR imaging findings for differentiating nonhemophilic hemosiderotic synovitis from diffuse-type tenosynovial giant cell tumor of the knee. Jpn J Radiol 39, 76–83 (2021). https://doi.org/10.1007/s11604-020-01034-z

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