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Electrophilic Reactions of 5-Aryltetrazoles: Synthesis of Isomeric 2-(Adamantan-1-Yl)-5-Nitrophenyl-2H-Tetrazoles and their Derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

The reaction of isomeric 5-nitrophenyl-NH-tetrazoles with adamantan-1-ol in concentrated sulfuric acid gave rise to new isomeric 2-(adamantan-1-yl)-5-nitrophenyl-2H-tetrazoles, nitration and reduction of which produced the corresponding dinitro and amino derivatives. The structures of the obtained compounds were proved by 1H, 13C NMR spectroscopy and high-resolution mass spectrometry. The thermal stability of the dinitro derivative was studied by the method of synchronous thermal analysis.

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Correspondence to Rostislav E. Trifonov.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2020, 56(7), 961–963

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Mikolaichuk, O.V., Spasibenko, D.V. & Trifonov, R.E. Electrophilic Reactions of 5-Aryltetrazoles: Synthesis of Isomeric 2-(Adamantan-1-Yl)-5-Nitrophenyl-2H-Tetrazoles and their Derivatives. Chem Heterocycl Comp 56, 961–963 (2020). https://doi.org/10.1007/s10593-020-02758-6

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  • DOI: https://doi.org/10.1007/s10593-020-02758-6

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