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Photoregulated macrocyclic cell-penetrating peptides (microreview)

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Chemistry of Heterocyclic Compounds Aims and scope

Light-controlled cell-penetrating peptides are reviewed as emerging photopharmacology tools. Key discoveries made recently in this area demonstrated that photoregulation of the cell-penetrating ability is very efficient in structural contexts of (macro)heterocyclic peptidic molecules, containing azobenzene or diarylethene photoisomerizable moieties.

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Financial support from Enamine Ltd. and Ministry of Education and Science of Ukraine (grant No. 18BP07-01) is acknowledged.

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Authors and Affiliations

  1. Enamine Ltd., 78 Chervonotkatska St, Kyiv, 02094, Ukraine

    Igor V. Komarov & Iuliia V. Bakanovych

  2. Taras Shevchenko National University of Kyiv, 60 Volodymyrska St, Kyiv, 01601, Ukraine

    Igor V. Komarov & Iuliia V. Bakanovych

Authors
  1. Igor V. Komarov
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  2. Iuliia V. Bakanovych
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Correspondence to Igor V. Komarov.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2020, 56(6), 719–721

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Komarov, I.V., Bakanovych, I.V. Photoregulated macrocyclic cell-penetrating peptides (microreview). Chem Heterocycl Comp 56, 719–721 (2020). https://doi.org/10.1007/s10593-020-02721-5

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  • DOI: https://doi.org/10.1007/s10593-020-02721-5

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