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Synthesis and Biological Activities of 4H-3,1-Benzothiazin-4-Ones

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Chemistry of Heterocyclic Compounds Aims and scope

4H-3,1-Benzothiazin-4-ones are accessible by various preparative routes mostly starting from anthranilic acid derivatives. These facile synthetic entries allow for the introduction of diverse substituents at positions 2 and 5–8. In this review, representative methods to generate 4H-3,1-benzothiazin-4-ones and the biological activities of the resulting products are highlighted.

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Authors and Affiliations

  1. Pharmaceutical Institute, Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, 53121, Bonn, Germany

    Lan Phuong Vu & Michael Gütschow

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  1. Lan Phuong Vu
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  2. Michael Gütschow
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Correspondence to Michael Gütschow.

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Published in Khimiya Geterotsiklicheskikh Soedinenii, 2020, 56(6), 708–714

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Vu, L.P., Gütschow, M. Synthesis and Biological Activities of 4H-3,1-Benzothiazin-4-Ones. Chem Heterocycl Comp 56, 708–714 (2020). https://doi.org/10.1007/s10593-020-02719-z

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  • DOI: https://doi.org/10.1007/s10593-020-02719-z

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